Sponsor the Course




Past Projects


2018 - 2019

Project Name Clinician/Sponsor
Delivering visual stimuli during MEG brain imaging Sumitomo Heavy Industries
Ultrasound probe support system Aaron Ross (MGH)
Optical imaging system for the middle ear to diagnose hearing loss
Masters Thesis ongoing
Dennis Poe, Buzz Kenney (Children's)
Portable device to help the physically impaired stand up Alan Ertel (Mt. Auburn)
Non-invasive sensing of breathing “work” in critically ill patients Ryan Carroll (MGH)
Preterm vaginal breech delivery device
To be published
Aliss Dangle (Tufts)
Patient aid to correct insulin syringe filling Richard Gyory, Bo Yang Yu (Becton Dickinson)
Delivery system for visceral organ repair compound
Winner 2019 Design of Med. Devices Student Showcase
Steve Mentzer (Brigham)
Distal radius fixation device Jay Connor (Mt. Auburn)

2017 - 2018

Project Name Clinician/Sponsor
Calf Stretching Device for Peripheral Arterial Disease Mazen Albaghdadi (MGH)
Lower Extremity Fracture Fixation Mazen Albaghdadi (MGH)
Crank-Powered Otoscope Michael Fuenfer (MGH)
In-Home Dialysis Fraser MacDonald & Franklin Segall (Mt. Auburn)
Cardiopulmonary Assessment Device Maulik Majmudar (MGH)
Monocyte Separation for Analysis of Immune Status Marc Normandin, Moses Wilks (MGH)
Adjustable Phantom for Radiotherapy Validation
Published ASME - 10.1115/1.4044402
Piotr Zygmanski, Yulia Lyatskaya
Personal Ambient Sensor Taku Nakahara, Chiai Takeda, Hidenari Nakayama (JTI)
Center-of-Gravity Detector for Operator Fatigue
Presented IEEE - 10.1109/EMBC.2018.8513526
Sumitomo Heavy Industries
Innovations in Breast Cancer Surgical Localization Constance Lehman, Christine Edmonds, Randy Miles, (MGH)
 Blue Light Therapy for Sterilization Frank Shuler (Marshall)

2016 - 2017

Project Name Clinician/Sponsor
Compact proton beam energy modulator Kyung-Wook Jee & Hsiao-Ming Lu
Musical instrument for MEG music studies
Presented IEEE - 10.1109/EMBC.2017.8036876
Erik Hornberger
Sumitomo Heavy Industries
Optimizing tools for vaginal delivery Sarah Lassey & Julian Robinson
Brigham and Women's
Development of a protective lead garment support
Published ASME -
Nishaki Mehta
Brigham and Women's
Low pressure mattress Ryan Lee
Thumb ligament mechanics Jay Connor
Mt. Auburn
Emergency naloxone delivery Ted Liao
Dehydration detection Maulik Majmudar
Precision medication dispenser Praveen Meka
Brigham and Women's
Long distance communication tool Shin Watanabe & Emma Tsuji

2015 - 2016

Project Name Clinician/Sponsor
Instrument for cells/vehicle injection under arthroscopy Shuichi Mizuno, PhD
BWH Orthopaedic Surgery
Cuffless blood pressure monitor Quan Zhang, PhD
MGH Psychiatry and Neurology
Hand surgery tools Jay Connor, MD
Mt. Auburn Hospital
SABR - surigcal acoustic biofilm removal Franklin Shuler, MD
Marshall University Orthopaedic Surgery
Device for assessment of frailty Maulik D. Majmudar, MD
MGH Cardiology
Mechano-chemical stimulation of bioengineered 3D tooth constructs Pamela Yelick, MD
Tufts University Orthodontics
Happiness Monitor Corporate Sponsor
Swim Brace Brandy Baker
Asthma integrated management system Christopher Fanta, MD
Brigham & Women’s Asthma Center
Bioreactor System for patient derived cell & tissue culture Christian Hirt, MD, PhD
Dana Farber Radiation Oncology

2014 - 2015

Project Name Clinician/Sponsor
Mallet finger splint Jay Connor, MD
Mt. Auburn Hospital
Compliant dental molar implant Gili Naveh. MD
Harvard Dental Medicine
Visually guidable suction catheter and applications in ICU
George Cheng, MD
Pulmonary Critical Care
Allowing two handed endoscopic ear surgery
Michael Cohen, MD
Mass Eye & Ear
Wearable defibrillator for survivors of acute myocardial infarction
Maulik D. Majmudar, MD
MGH Cardiology
Development of customized ankle foot orthotics
Brandy Baker
Semi-automated tube thoracostomy insertion system
Tomaz Mezar, MD
MGH Surgery
A Remote-Sensing Pulse Oximetry Device
Michael M. Fuenfer, MD
MGH Pediatric ICU

2013 - 2014

Project Name Clinician/Sponsor
A Rapid Cooling Device for Induction of Hypothermia Among Victims of Cardiac Arrest
Maulik D. Majmudar, MD
MGH Cardiology
Emergency Tourniquet
Jay Connor, MD
Mt. Auburn Hospital
Accurate Bone Drill
Ambrose Huang, MD
MGH Radiology 
Prevention of Pressure Ulcers in Spinal Cord Injury Patients via Global Positioning System Technologies
Vidya Jayawardena, MD
VA Boston, Spinal Cord Injury
Simplified Dermatome
Robert Sheridan, MD
Novel Resectoscope for Increased Patient Safety, Decreased Surgeon Pain During Urologic Surgery
Joseph Ciccone, MD
BWH Urology
Device and Method for Diagnosing Eustation Tube Dysfunction
George "Buzz" Kenney
Dennis Poe
Children's Otolaryngology 
Improved Delivery System for HCG Therapy
Ravi Kacker, MD
BIDMC Surgery (Urology)
Omax Design & Solar PV
Speical Projects

2012 - 2013

Project Name Clinician/Sponsor
Optimization of intra-aortic balloon pump
T. Anthony Anderson, PhD, MD
MGH Anesthesia
Portable infant warmer Michael M. Fuenfer, MD
MGH Pediatric ICU
Bandage for US Navy dolphins Stephen Ferrara, MD, CDR, MC, USN
Roderick C. Borgie, MD
Eric Jensen
US Navy
Electrosurgery energy measuring method Kamal Itani, MD VA
Boston, Surgery
Cardiac fluid status monitor Maulik D. Majmudar, MD
Brigham & Women’s Emergency
Improved single lumen endotracheal tube Ian Makey, MD
BIDMC Cardio Thoracic Surgery
Uterine manipulator John C. Petrozza, M.D.
MGH Gynecology 
UltraFast ultrasound probe sheathing J. Jordan Romano, MD
MGH Hospital Medicine
Endoscopic sub-mucosal dissection knife Corporate Sponsored Project

2011 - 2012

Project Name Clinician/Sponsor
A Design of New Instrument for Liver Resection
Jiping Wang, MD, PhD
BWH - Surgical Oncology
Patient Repositioning Aaron R. Ross, CPE
Partners  - Occupational Health
Rapid Skin Closure Device for Long Surgical Incisions Kyle R. Eberlin, M.D.
MGH – Plastic Surgery
MIS Specimen Removal - Video Ian Makey, MD
BIDMC – Cardio Thoracic Surgery
Improving Fine Needle Aspirations Sareh Parangi, MD
MGH – Cancer Center
02 Pump John N. Kheir, M.D.
Children’s – Cardiac ICU
Dental Chair Headrest Teruaki Ito
University of Tokushima
Energy Focus
Wave Energy Pump
Developing the world's first wave driven desalination system that can cost-effectively provide rapid relief for people who live in coastal communities without adequate water or electrical infrastructure. The system is principally powered by pressurized seawater pumped onshore from wave energy converter.
Full Description
Wood Pellet Stove
Many houses in New England are heated with non-renewable oil.  However, New England still has large, managed forests, left over from the former paper industry, which have the potential to supply wood pellets which, when burned in a modern pellet stove, are an efficient renewable way to heat a house. Most pellet stoves are expensive and require electricity to operate; your task is to consider a typical New England home with a fireplace and basement, and create an efficient and autonomous wood pellet stove product.
Full Description



Esophageal atresia nonoperative correction

Long-gap esophageal atresia is a congenital disorder occurring in approximately 100 newborn infants every year characterized by a discontinuity in the esophagus between the mouth and stomach. This project investigated the use of internal permanent magnets to stretch the proximal and distal esophageal pouches together until anastomosis occurs. The system implements a hydraulic and magnetic mechanism, with optical gap sensing, to apply controlled, adjustable forces from inside the pouches. This could potentially lead to a novel treatment for a tragic condition.

Team: Austin L. Oehlerking, James D. Meredith, Ian C. Smith, Phillip M. Nadeau, Teresa Gomez, Zachary A. Trimble, David P. Mooney (Children’s), David L. Trumper

Half of magnet assembly

Improved nasal gastric tube tip and flushing device

Nasogastric tubes are commonly used to evacuate the stomach during cases of small obstructive bowel syndrome and surgical operations, unfortunately the tube tip and bore is prone to clogging.  A redesigned tube tip featuring helical slits, rather than holes, reduces clogging by both food particles and suction against the stomach mucosa. Should a clog still occur an in-line flusher has been developed that, with a single squeeze, can disconnect the vacuum, deliver a saline purge and reconnect the vacuum. Reduced clogging and easier flushing will improve patient comfort and reduce nursing staff workload.

Team: James A. Ankrum, Alison L. Olechowski, Jose A. Canseco, Elliot E. Greenblatt, Michael P. Roberts, Robert Brick, Dr. Ali Tavakkolizadeh (BWH)

Improved tip and flusher device

Patented, Available for License
Single entry tunneler [SET] for hemodialysis graft procedures

Vascular tunnelers are used to create a path through subcutaneous tissue for the placement of grafts, particularly for hemodialysis access. Most current designs are rigid and require high forces and multiple incisions to complete even the most simple path geometries. This project investigated a three-stage design consisting of concentric, nested tubes: a straight stainless steel tube; a second pre-curved nitinol tube and a straight nitinol tube. By deploying the stages in this order the device is able to produce an approximately 180◦ looped path through tissue. An illuminated tip provides visual feedback of the tip trajectory under the skin. This has the potential to reduce tissue trauma and the risk of post-operative infection.

Team: Madalyn S. Berns, Elizabeth Y. Tsai, Jesse Austin-Breneman, James C. Schulmeister, Edward Sung, Conor J. Walsh, Charles K. Ozaki (BWH)

Curved tunneler and dilator

Innovative renal cooling device for use in minimally invasive surgery - Video

Over 58,000 patients suffer from renal cell carcinoma annually in the US and treatment often requires surgical removal of the cancerous tissue via a partial nephrectomy. In open renal surgery, the kidney is placed on ice to increase allowable ischemia time; however there is no method for reducing kidney temperature during minimally invasive surgery. The device consists of a foldable bag that deploys through a 12 mm trocar, unfurls inside the abdomen then wraps around the kidney and is filled with ice slurry. Testing indicates that kidney core cooling to 20°C can be obtained in under 10 minutes, whereupon the water can then be suctioned out and the device removed, leaving the kidney ready for surgery with a longer working time.

Team: Edward Summers, Thomas Cervantes, Rachel Batzer, Julia Stark, Raymond Lewis, Christie Simpson, Dr. Nadeem Dhanani (Mt. Auburn)

Cooling bag wrapped around model kidney

Medical Eng. & Physics Paper
Patented, Available for License
Somnus Sleep Sensing Shirt - home sleep monitoring

Over 1 million sleep studies are performed annually in the US to detect chronic sleep disorders. Currently these require a patient to spend a night in a clinic connected to up to 30 sensors, ranging from brain wave electrodes to blood oxygen trackers. Data from these studies are divided into time segments and which are manually categorized into various sleep states in a costly process. The Somnus Sleep Shirt package is comprised of a snug fitted shirt, embedded with simple capacitive displacement sensors that monitor the respiration of a sleeping patient and a novel software package and algorithm that automates sleep scoring. This combination has been shown to analyze sleep with accuracy comparable to current sleep laboratory methodology, with greatly reduced technical requirements, at low cost and while achieving a higher level of comfort and convenience for the user.

Team: Thomas S. Lipoma, Pablo J. Bello, Carson J. Darling, Matthew Bianchi (MGH)
Pressure sensing laparoscopic grasper

Most laparoscopic graspers provide minimal tactile feedback and create pinch points in the grasped region, often resulting in either excessive grasp forces or tissue slippage. Tissue trauma can occur. This research presents a proof-of-concept for a parallel motion, pressure sensing laparoscopic grasper which eliminates pinch points in the grasped region and applies a uniform pressure across the grasper jaws. A low cost pressure sensor provides feedback to the handle when a preset threshold force is applied. Testing results from a 2x scale prototype were close to analytical predictions and allowed grasper pressure to be monitored.

Team: Grace S. L. Teo, Mattias S. Flander, Toomas R. Sepp, Manuel Corral, Juan D. Diaz, Alexander Slocum, Khashayar Vakili (Children’s)

Parallel gripper with force detection

Flexural laparoscopic grasper - Video

Laparoscopic surgery requires complex manipulation and movement of internal organs. While small incisions make laparoscopic surgery an attractive procedure, current laparoscopic devices hinder surgeons' capabilities with limited degrees of freedom. Specifically, needle nose end effectors pinch organs and can cause tissue perforation. To enhance surgical capacity, a three fingered laparoscopic device was designed, fabricated and tested. Flexures with tendon-like control cables are used to provide three points of articulation in each finger. To integrate with current laparoscopic procedures, the device fits through a 12mm trocar port. An ergonomic handle allows the fingers to be easily actuated and locked in position. Testing the device with organ-like objects revealed an increased ability to grasp, move and otherwise engage items.

Harry O'Hanley, Matt Rosario, Yuanyu Chen, Audrey Maertens, John Walton, Mitchell T. Westwood, Jennifer Rosen (BMC)

Gripper with flexural fingers

OneShot One Handed Glucometer
Typical blood glucose monitoring systems that consist of glucometers and lancing devices do not account for the needs of diabetics whose physical or mental conditions limit their dexterity. This project proposes an integrated blood glucose monitoring system that operates with a finger press that combines lancing and blood withdrawal into a single fluid step using an electromechanical actuation system, not found in lancing devices or glucometers currently on the market. The complexity of taking a blood glucose measurement is reduced by 40%.
Santiago Alfaro, Harrison Bralower, Linda Liu, Jennifer Milne, James Regan (VA Boston)


Comparison showing reduction in steps


Representative Earlier Projects

Robopsy - 2004
Robopsy, a robotic device to assist radiologists performing tumor biopsies was invented by an MIT 2.75 team led by MGH's Rajiv Gupta, MD.  The team has been awarded the 2007 MIT $100K prize, the world's leading entrepreneurship competition and the first-place award at the 2008 ASME Innovation Showcase.
See website for all Information
Enhanced ACL Repair- 2004
Dr. Martha Murray of Children’s Hospital developed a cell-friendly gel containing platelets and collagen to serve as a scaffold to enable torn anterior cruciate ligament (ACL) healing, but needed a way to way mix, warm and inject the gel into the target location.  She turned to CIMIT and 2.75 to develop a handheld “gel gun,” employing a heater and a collapsible augur, which is capable of precisely preparing, metering and arthroscopically injecting the gel through a 1 cm incision. The third generation device and the gel is undergoing testing with results indicating significantly stronger ACL repairs. Dr. Murray is working to turn her technology into a start-up company devoted to improving the treatment of over 200K ACL repair patients per year.
Read more here and be sure to watch the video.
ACL Gun ACL gun
Endoscopic Biopsy Needle w/ Flexural Members - 2005
Current endoscopic biopsy needles are relatively unreliable in operation and incapable of preserving the tissue histology. This research developed a new of coring biopsy needle with small laser cut flexural barbs along the inside.  Upon insertion into tissue they bend out of the way and then upon retraction of the needle they firmly grab the tissue sample and sever it.   The needle has been fully prototyped in stainless steel, testing indicated increased sample yield and structural robustness. ASME J. Medical Devices Paper
biopsy needle
GRiT Chair Alarm - 2007
The Gesture Recognition Interactive Technology (GRIT) Chair Alarm aims to prevent falls for at risk patients. The alarm uses an array of proximity and pressure sensors to create a map of the patient’s sitting position and then uses gesture recognition algorithms to determine when a patient is attempting to stand up and responds with light and voice alarms and activates the integrated nurse-call function. IEEE EMBS
Endotracheal Tube Placement Sensor - 2007
Placing an endotracheal tube (ETT) at the correct location requires a high level of skill and training.  Our group has developed a hand-held ETT placement sensor which allows a doctor to “see” the tube’s position in the throat. It uses an array of Giant Magnetoresistive sensors to localize the position of a tiny magnet embedded in the ETT. The entire device is rechargeable and designed to fit comfortably into the hand. IEEE EMBS
Osmoregulation - 2007
There is a continued need for a non-invasive method to accurately measure the level of hydration in human beings. Our method uses low power RF energy from 100 kHz to 10 MHz to measure the loss tangent of the frontal is muscle (in the forehead) which is a function of tissue osmolality and hematocrit, which are strong indicators of hydration.
Smartpad - A Wireless, Stickerless EKG System - 2007
During an operation, the patient's vital signs are displayed in the operating room. The large number of wires attached to the patient inhibits the medical team's access and the electrodes may not be placed in convenient locations. We present the SmartPad: a device that displays a patient's electrocardiogram (EKG) signal without adhesives or wires. Instead, our sensors are bonded to a foam mat, on which the patient lies during the operation. IEEE EMBS
Mechanical Needle Clutch - 2009 Current methods of trocar and needle placement into hollow organs rely on a high degree of clinical skill to stop inside the organ and not over penetrate. To address this, a purely mechanical clutch was developed which comprises buckled filament inside an S-shaped tube (the trocar or needle). When pushed against firm tissue the filament buckles and locks within the tube, causing the filament and tube to advance as one. When the needle reaches the target tissue or fluid-filled cavity, the filament unlocks and slides freely into the target region while the tube remains stationary. PNAS Paper

Publications List

    • Mitha, A.P., Ahmad, M.S., Cohen, S.J., Lieberman, J.S., Udengaard, M.R., Slocum, A.H., Coumans, J.C.E., 2010, A Modified Footplate for the Kerrison Rongeur, ASME Journal of Medical Devices, March, vol. 4, p. 014502-1 - 014502-4. [PDF]
    • Chen, Y., Chang, J., Greenlee, A.S., Cheung, K.C., Slocum, A.H., Gupta, R., Multi-turn, Tension-stiffening Catheter Navigation System, Proc. of 2010 IEEE ICRA, May 3-8, 2010, Anchorage, Alaska. [PDF]
    • Petrzelka, J.E., Chatzigeorgiou, D.M., Menon, M.C., Lustrino, M.E., Stefanov-Wagner, C.J., Slocum, A.H., and Agarwal, S.K., 2001, An Articulating Tool For Endoscopic Screw Delivery, Proc. of the 2010 Design of Medical Devices Conference, April 13-15, 2010, Minneapolis, MN, USA. [PDF]
    • Slocum Jr., A.H., Duffley, S.C. Moreau, J.G., Watral, A., Spiegel, J.E., Slocum, A.H., Design of a Pressure Measuring Syringe, Proc. of the 2010 Design of Medical Devices Conference, April 13-15, 2010, Minneapolis, MN, USA. [PDF]
    • Anderson, S.J., Zimmermann, J.C., Houston, E.F., Farino, K.M., Begg, N.D., 2010, Design of an Endoscopic Lens Shielding Device for use in Laparoscopic Procedures, Proc. of the 2010 Design of Medical Devices Conference, Minneapolis, MN, USA, Mar. 13-15, DMD2010-3849. [PDF]
    • Al Husseini, A.M., Lee, H.J., Negrete, J., Powelson, S., Servi, A., Sloucm, A., Saukkonen, J., 2010, Design and Prototyping of a Low-cost Portable Mechanical Ventilator, Proc. of the 2010 Design of Medical Devices Conference, Minneapolis, MN, USA, Mar. 13-15, DMD2010-3845. [PDF]
    • del Pozzo, D., Eggenspieler, D., Slocum, A., Deterre, M., Lobovsky, M., Pigula, F., Hydraulically Remote Adjustable Pulmonary Artery Banding, Proc. of the 2010 Design of Medical Devices Conference, Minneapolis, MN, USA, Mar. 13-15, DMD2010-3879. [PDF]
    • E.K. Bassett, A.H. Slocum, P.T. Masiakos, H.I. Pryor, O.C. Farokhzadb, J.M. Karp, Design of a mechanical clutch-based needle-insertion device, Proc. of the National Academy of Sciences, 2009 [PDF1, PDF2]
  • Knight, H., Lee, J., Ma, H., 2008, Chair Alarm for Patient Fall Prevention based on Gesture Recognition and Interactivity, Proc. 30th Annual International IEEE EMBS Conference, Vancouver, British Colombia, Canada, Dec. 20-24, p. 3698-3701, 978-1-4244-1815-2/08. [PDF]
  • Chen, F., Wu, H., Hsu, P., Stronger, B., Sheridan, R., Ma, H., 2008, SmartPad: A Wireless, Adhesive-Electrode-Free, Autonomous ECG Acquisition System, Proc. 30th Annual International IEEE EMBS Conference, Vancouver, British Colombia, Canada, Dec. 20-24, p. 2345-2348, 978-1-4244-1815-2/08. [PDF]
  • Wichakool, W., Pierquet, B., Durand, K., Hsu, B., Sheridan, R., Ma, H., 2008, Magnetic Endotracheal Tube Imaging Device, Proc. 30th Annual International IEEE EMBS Conference, Vancouver, British Colombia, Canada, Dec. 20-24, p. 2345-2348, 978-1-4244-1815-2/08. [PDF]
  • McEuen, S., Tzeranis, D., Hemond, B., Dirckx, M., Lee, L., Slocum, A.H., 2008, Design of an Endoscopic Full-Thickness Lesion Removal Device,” ASME Journal of Medical Devices, March, vol. 2, p. 015002-1 - 015002-8. [PDF]
  • Walsh, C.J., Hanumara, N.C., Slocum, A.H., Shepard, J, Gupta, R., 2008, “A Patient-Mounted, Telerobotic Tool for CT-Guided Percutaneous Interventions,” ASME Journal of Medical Devices, March, vol. 2, p. 011007-1 - 011007-10. [PDF]
  • Figueredo, S.L., Brugge, W.R., Slocum, A.H., 2007, Design of an Endoscopic Biopsy Needle with Flexural Members,” ASME Journal of Medical Devices, March, vol. 1, p. 62-69.. [PDF]
  • Walsh, C.J., Hanumara, N., Slocum, A., Gupta, R., Shepard, J., 2007 Evaluation of a Patient-Mounted, Remote Needle Guidance System for CT-Guided, Percutaneous Lung Biopsies, Proc. of BioMed Conference, Irvine, CA, USA, June 7-8, BioMed2007-38080. [PDF]
  • Hanumara, N.C., Walsh, C.J., Slocum, A.H., Gupta, R., Shepard, J., 2007, Human Factors Design for Intuitive Operation of a Low-cost, Image-Guided, Tele-Robotic Biopsy Assistant, Proc. of the 29th Annual International Conference of the IEEE EMBC, Lyon, France, Aug. 23-26, p. 1257-1260, ThP2D4.7. [PDF]
  • Barrett, S.R.H., Hanumara, N.C., Walsh, C.J., Slocum, A.H., Gupta, R., Shepard, J.O., 2005, A Remote Needle Guidance System for Percutaneous Biopsies, Proc. IDETC/CIE Conference, Long Beach, CA, USA, Sept. 24-28, DETC2005-85387. [PDF]