Course:>> Course 5:>> Spring 2007:>> 5.512:>>  Lecture Notes and Syllabus

Lecture Notes and Syllabus

 

Please note that this schedule is tentative and may change during the course of the semester

Lecture
Date
Topic
Notes
Readings
01
2/28
Strategies for Stereocontrolled Synthesis I
G&A 1; O'L 1
02
3/02
Strategies for Stereocontrolled Synthesis II
G&A 1; O'L 1
03
3/05
Strategies for Stereocontrolled Synthesis III
G&A 1; O'L 1
04
3/07
Stereocontrolled Alkylation I
G&A 3, 8.4; O'L 2, 3, 29
05
3/09
Stereocontrolled Alkylation II
G&A 3, 8.4; O'L 2, 3, 29
06
3/14
Stereocontrolled Alkylation III
G&A 3, 8.4; O'L 2, 3, 29
07
3/16
Stereocontrolled Alkylation IV
G&A 3, 8.4; O'L 2, 3, 29
08
3/21
Stereocontrolled Conjugate Addition I
G&A 4.4, 5.3; O'L 9, 10, 16, 17
09
3/23
Stereocontrolled Conjugate Addition II
G&A 4.4, 5.3; O'L 9, 10, 16, 17
10
4/02
Stereocontrolled 1,2 Addition to C=X Bonds I
G&A 4.1-4.3; O'L 7, 8
11
4/04
Stereocontrolled 1,2 Addition to C=X Bonds II
G&A 4.1-4.3; O'L 7, 8
12
4/06

Stereocontrolled 1,2 Addition to C=X Bonds III & Addition of Allylmetals to Carbonyls I

G&A 4.1-4.3; O'L 7, 8 & G&A 5.1; O'L 11
13
4/20
Addition of Allylmetals to Carbonyls II G&A 5.1; O'L 11
14
4/23
Addition of Crotylmetals to alpha-Chiral Aldehydes & Stereocontrolled Aldol Reactions I

G&A 5.1; O'L 11 &
G&A 5.2; O'L 12-15

15
4/25
Stereocontrolled Aldol Reactions II G&A 5.2; O'L 12-15
16
4/27
Stereocontrolled Aldol Reactions III
G&A 5.2; O'L 12-15
17
5/02
Stereocontrolled Carbonyl Reduction
G&A 7.1; O'L 22
18
5/04
Stereocontrolled Hydrogenation and Hydroboration
G&A 7.2, 7.3; O'L 24
19
5/09
Stereocontrolled Dihydroxylation & Epoxidation I
G&A 8.2, 8.3; O'L 26-28
20
5/11
Stereocontrolled Epoxidation I Case Study & Stereocontrolled Epoxidation II
G&A 8.2; O'L 26, 27
21
5/14
Problems in Stereocontrolled Synthesis