Fall 2001 Reading Assignments, Developmental Biology
Please note, Lectures 1-18 have been moved below the lectures for Oct. 24-Dec. 3. This makes the assumption that you have read all the oldest assignments, but they remain here for archival purposes.
The textbook information is also at the bottom of this page.
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Lecture Date
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Title
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Required Reading
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Background/optional
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| Oct 24th | Vertebrate Overview/Axis Form. I |
Chap 4. Techniques,
pp.92-100; |
Chap 5. Gene structure, promoters transcription factors, pp.109-119 Chap 6. Paracrine Factors, pp.149-156 |
|
Oct. 26th Oct. 29th |
Axis Form I- II Axis Form II |
Chap 22. Sog/Chordin, dpp/BMP 4, pp.690-682Chap 11. Devel & Axis Form. Birds, Mammals, pp.345-361. Chap.12 CNS/Neural.,pp.379-385. | Chap. 11Fish Dev. pp339-345; Mammal. Extraembry. Mem Dev.pp 361-363 Chap 12 Second Neural.pp385-386 |
| Oct. 31st |
AP Patterning and Cell proliferation |
Chap
12. A/P in Neural Tube, pp.386-388; Cell proliferation and morph in brain:pp389-398 |
Chap 21. Teratogens, pp.664-673 |
| A/P Patterning II |
Chap11: Mammals
Hox code 364-369 |
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| Nov. 5th | A/P Patterning III | Rhombdomeres pp.697-698 Chap 13. Cranial Neural Crest, pp.417-420 | |
| Nov. 7th | D/V Patterning I | Chap
12. DV patterningCNS 388-389 Homologies in Nerve Cell Induct..Achaete/scute,
pp398-99 HANDOUT Mole. & Cell : Neuron Phenotype Chap 14: Patterning of Mesoderm pp447-453 |
Chap 12. Adult Neural Stem Cells, pp.394-396 |
| Nov. 9th | D/VII +Limb Devel. I | Chap
3. Limb Fields, pp.64-65 Chap 14. Paraxial Mesoderm and Muscle Differen., pp.447-454 |
Chap 18. Fly Imaginal Discs, pp.559-562 |
| Nov. 14th | Limb Devel. II | Chap
15. Lateral Plate Mesoderm, p.471 Chap 16. Devel. of the Tetrapod Limb, pp.503-519 |
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| EXAM II | Will Cover through D/V patterning | ||
| Nov. 19th | LIMB/Neural Crest I | Chap 13. Trunk Neural Crest, pp.411-417 | |
| Neural Crest II | HANDOUT
Neural Crest Lineage and Migration Kalthof Chap 13pp.319-328 |
Chap 13. Tooth & Cardiac Neural Crest, pp.420-422 | |
|
Nov. 20th Nov. 28th |
Neuromuscular Innervation | Chap
13. Motor Neuron Specification for termination, pp.423-425 HANDOUT MOTONEURON OUTGROWTH |
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| Dec. 3rd | Eye Devel. | Chap 6. Induction & Competence In Eye Devel., pp.143-147 | |
| Dec. 5th | Axon Growth in the Brain | Chap 13. Pathway Selection Guidance Molecules and Termination, Ephrins & Eph receptors, pp.425-438 |
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From TEXT: Developmental Biology; Author:
Gilbert
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| Lecture 18 Handouts: |
1) Kalthoff Chapter 28 pp.743-768 | ||
| 2) Conlon and Raff ìSize control in animal developmentî Cell, 96:pp.235-244 | |||
| Lecture 17 | Chapter 6 pp. 143-176 | cell-cell communication | |
| Chapter 16, pp. 517-518 | apoptosis in vertebrate digits | ||
| Lecture 16 | Chapter 5 pp. 126-135 | dosage compensation | |
| Lecture 15 | Chapter 17, pp. 523-543 | sex determination | |
| Lecture 14 | Chapter 6, pp. 157-158 | vulval induction | |
| Chapter 6, pp. 169-170 | lateral inhibition | ||
| Lecture 13 | Chapter 6, pp. 165-167 | apoptosis in worms | |
| Lecture 12 | Chapter 8, pp. 251-257 | C. elegans overview | |
| Lecture 11: | Chapter 6, pp. 156-157 | drosophila eye | |
| Chapter 5, pp. 116-122 | pax-6 | ||
| Chapter 4, pp. 103-104 | aniridia | ||
| Lecture 10: | Chapter 18, pp. 556-565 | imaginal discs | |
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Lecture 9:
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Chapter 9, pp. 167-170 | Notch signaling | |
| Chapter 12, pp. 398-399 | proneural genes | ||
| Chapter 13, pp. 425-431 | axon guidance | ||
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Lecture 8:
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Chapter 9, pp. 285-290 | homeotics | |
| Chapter 22, pp. 679-694 | evo-devo | ||
| Chapter 11, pp. 365-369 | hox genes in vertebrates | ||
|
Lecture 7:
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Chapter 9 pp. 278-285 | segmentation | |
| Lecture 6: | Chap. 2, pp. 44-46; | Evolution | |
| Chapter 9, pp. 269-277 | maternal control of axial patterning | ||
| Chapter 9, pp. 290-298 | D/V patterning | ||
| Recommended: | |||
| Kalthoff 2nd edition ìAnalysis of Biological Developmentî Chapter 22 | |||
| Lecture 5: | Chapter 19, pp. 608-610 | oogenesis | |
| Chapter 19, pp. 587-588 | germ cell determination | ||
| Lecture 4: | Chap. 14, pp. 585-597; 599-604; & 608-613; |
Gametogenesis | |
| Optional: | Chap. 17, pp. 524-535; | Sex Determination | |
| Chap. 7, pp. 185-195; 198-199; 202-206; & 210-213 | Fertilization | ||
| Lecture 3: | Chap. 3, pp. 54-74; | Regulative Developmental Determination and Specification | |
| Chap. 10, pp. 303-314; | Cleavage Gastrulation | ||
| Lecture 2: | Chap. 2, pp. 25-30; | Frog Morphogenesis | |
| Chap. 5, pp. 109-123; | Differential Gene Transcription | ||
| Chap. 5, pp. 130-132; | Differential RNA Processing | ||
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Lecture 1:
|
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Chap. 5, pp. 125-126; | DNA Methylation |
| Chap. 4, pp. 79-89 & pp. 100-102; | Germline Gene Therapy | ||
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BOOKS ON RESERVE IN RESERVE BOOK ROOM: |
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| Gilbert S.F (2000) Developmental Biology 6th edition Sinauer Assoc, Inc., Sunderland MA (students are advised to buy this text) | |
| Reserve Texts: | Wolpert et al., (1998) Principles of Development Current Biol. LTD, NY, London, Oxford Univ Press, Oxford, NY Tokyo |
| Kalthof, K. (2001) Analysis of Biological Development 2nd edition McGraw Hill, Boston | |
| Slack, J. (2001) Essential Developmental Biology Blackwell Science Oxford, London, Edinburgh & Malden MA | |
| Beir, E. (2000) The Coiled Spring: How Life Begins Cold Spring Harbor Laboratory Press Plainview NY | |
| Gerhart J & Kirschner, M (1997) Cells, Embryos, and Evolution Blackwell Science Oxford, London, Edinburgh & Malden MA. | |
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Copyright © 2001 Massachusetts Institute of Technology. All rights reserved.