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7.61 Eukaryotic Cell Biology



The materials and information for this class can be found on Stellar.


Course Description:


Emphasizes methods and logic used to analyze eukaryotic cells in diverse systems (e.g., yeast, fly, worm, mouse, human; development, neurons).

Subject combines lectures and in-depth roundtable discussions of literature readings with active participation of faculty experts. Focuses on membranes, organelles, the cell surface, cytoskeleton and extracellular matrix.

Topics include:
membrane protein structure, cell surface receptors and transporters;
signal transduction pathways;
membrane trafficking/sorting/secretion;
adhesion and its effects on organization, migration and polarity of cells;
regulation of the cell cycle;
integration of cells into tissues and organs.

Ranges from basic studies to applications to human disease, while emphasizing critical analysis of experimental approaches. Limited enrollment.