8.592J: Statistical Physics in Biology

Spring 2018

NB. This outline is subject to change as term progresses.


TENTATIVE OUTLINE

Lec. 1 (2/6) MK
Introduction; Master equation

Lec. 2 (2/8) LM
Elements of population genetics

Lec. 3 (2/13) MK
Evolving populations (forward Kolmogorov)

Lec. 4 (2/15) MK
Population genetics (fitness, selection, ...) 

Lec. 5 (2/22) MK
Fixation (backward Kolmogorov)

Lec. 6 (2/27) MK
Electrostatic (ionic)interactions 

Lec. 7 (3/1) MK
Polymer theory 1, entropy elasticity, collapse   

Lec. 8 (3/6) LM
Population Genetics of  Cancer 

Lec. 9 (3/8) LM
Protein folding I: elements of structure and forces

Lec. 10 (3/13) MK
Polymer theory 2, collapse, Random energy model

Lec. 11 (3/15) LM
Protein folding II: structure

Lec. 12 (3/20) LM
Protein folding, kinetics and design

Lec. 13 (3/22)  MK
DNA (melting)

Lec. 14 (4/3) MK
RNA (secondary structure)

Lec. 15 (4/5) LM
Protein-DNA binding

Lec. 16 (4/10)   MK
Microtubules

Lec. 17 (4/12)   MK
Molecular motors & cell motility

Lec. 18 (4/19) LM
Protein-DNA  kinetics

Lec. 19 (4/24)   LM
Cooperativity

Lec. 20 (4/26)   LM
Biological Networks

Lec. 21 (5/1) MK
Introduction to networks

Lec. 22 (5/3) MK
Dynamics on networks   

Lec. 23 (5/8) LM
Chromatin I

Lec. 24 (5/10)  LM
Chromatin II

Lec. 25 (5/15) MK
Collective behaviors in time & space

Lec. 26 (5/17) MK
Collective behaviors in time & space


  • 8.592 Course Outline - last update 4/2/18 by M. Kardar