Sequence information & evolution

1. Elements of population Genetics:

  • Mutations, Fitness, selection
  • Fixation
2. Mathematical tools:
  • Transition probability matrix; approach to steady state
  • Master equation
  • Forward and backward Kolmogorov equations
  • Mean first passage time

L1: (MK) Introduction and evolving probabilities

L3: (LM) Elements of population genetics

L4:  (LM) Fitness landscapes

L2: (MK) Forward Kolmogorov equation

L5:  (MK) Backward Kolmogorov equation

lec1- Sequence