8.592 - HST.452J (Spring
2024)
Statistical Physics
in Biology
Lecture 12
RNA secondary structure
- Structure and function of RNA (wikipedia)
- The
'RNA world' hypothesis
- Structural
levels:
- Representations
without psuedoknots
- Algorithms for finding optimal secondary structure: Nussinov
(article),
unafold web-server (M. Zuker)
- Recursive
calculation of partition function
- RNA folding and Matrix Field Theory (McGenus)
- Counting secondary structures. [Chandrasekhar, Rev. Mod. 15, 1 (1943)]
- Thermal denaturation of RNA
- The
melting of a hairpin
Lecture notes
8.592 lecture- last update 10/17/2024 by M. Kardar