8.592 - HST.452J (Spring 2022)
Statistical Physics in Biology
Lecture 12
(Please note that lecture is being recorded)
8.592 in 4-265 on 02/28/2022 at 2:30PM
Phases of Polymers
Interacting polymers:
Entropy; excluded volume; and solvent-mediated interactions
Mean-field estimate of the partition function
Swollen (coil) phase in good solvents
Flory exponent
Scaling behavior in other dimensions
Compact (globular) phase in poor solvents
Polymer collapse, theta-point
Thermodynamic behavior at the transition; reduction in entropy
Frozen (folded) state of heteropolymers
The Random Energy Model (REM)
The freezing transition and associated singularities
Designed REM as a model of protein folding
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Lecture notes
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8.592
lecture- last update 2/27/22 by M. Kardar