8.592 - HST.452J (Spring 2024)

Statistical Physics in Biology

Lecture 9


Population Genetics of Cancer

  1. Haldane's equation for fixation of
  2. Hallmarks of cancer:
  3. Model of tumor progression


Some useful links:

Copy-number changed in cancer https://portals.broadinstitute.org/tcga/home

Somatic mutation in cancer and normal cells https://pubmed.ncbi.nlm.nih.gov/26404825/

(Slides from Mirny)

(Mirny Lecture Notes)

(Kardar Lecture Notes, slightly updated)


8.592  lec8- last update    10/7/24     by M. Kardar