Publications
Xue H, Guo R, Wen Y, Liu D, Huang L: An abundant DNA binding protein from the hyperthermophilic archaeon Sulfolobus shibatae affects DNA supercoiling in a temperature-dependent fashion. J Bacteriol 2000 Jul;182(14):3929-33
Wang G, Guo R, Bartlam M, Xue H, Yang H, Liu Y, Huang L, Rao Z: Expression, purification, crystallization and preliminary X-ray analysis of a DNA-binding protein from Methanococcus jannaschii. Acta Crystallogr D Biol Crystallogr 2002 Jul; 58(Pt 7): 1240-2
Bu D, Zhao Y, Cai L, Xue H, Zhu X, Lu H, Zhang J, Sun S, Ling L, Zhang N, Li G, Chen R: Topological structure analysis of the protein-protein interaction network in budding yeast. Nucleic Acids Res. 2003 May 1; 31(9): 2443-50
Cui Q, Tong Y, Xue H, Huang L, Feng Y, Wang J. Two conformations of archaeal Ssh10b: The origin of its temperature dependent interaction with DNA. J Biol Chem. 2003 Dec 19; 278(51): 51015-22. Epub 2003 Sep 30.
Wang G, Guo R, Bartlam M, Yang H, Xue H, Liu Y, Huang L, Rao Z. Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeon Methanococcus jannaschii. Protein Sci. 2003 Dec; 12(12): 2815-2822.
Guo R, Xue H, and Huang L. Ssh10b, a conserved thermophilic archaeal protein, binds RNA in vivo. Mol Microbiol. 2003 Dec; 50(5): 1605-15
Research Interests
‣Horizontal gene transfer and the origin of the new genes.
‣Genetic relationship among bacteria in microbial communities.
‣Environmental genomics with emphasis on composition of the mobile DNA pool.
‣Adaptive evolution of bacteria to their changing environment.

Education
1998 - B.S, Sichuan University, P.R. China
2005-present Graduate student, MIT
Hong Xue

Graduate Student
Department of Civil and Environmental Engineering
MIT 48-418
77 Massachusetts Avenue
Cambridge, MA 02139
Phone: (617) 253-8650 Fax: (617) 253-7475
Email: hongxue(at)mit.edu