Kevin Fowler Graduate Student Department of Chemical Engineering Room E19-536 Phone: 617-252-1744 Fax: 617-253-2272 E-mail: kfowler@mit.edu Co-stimulatory molecules serve to enhance (CD28, ICOS) or inhibit (CTLA-4) TCR signals and also affect cell cycle progression, differentiation, and anergy development. I am interested in determining the effect of co-stimulation in the context of autoimmune disorders.