Chakraborty LabMIT  
  Chakraborty Lab  
  ResearchPublicationsPeopleCollaborationsTeachingContact InformationStochastic Simulation Compiler  
   
    Publications 2009 - 2010

125. "Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells", with J. Das et al, Cell, 136, 337 (2009)

126. "Origin of the sharp boundary that discriminates positive and negative selection of thymocytes", with A. Prasad et al, PNAS, 106, 528 (2009)

127. "Signaling Cascades Modulate the Speed of Signal Propagation through Space", with C. Govern, PLOS One, 4 (2009)

128. "Positive feedback regulation results in spatial clustering and fast spreading of active signaling molecules on a cell membrane", with J. Das et al, J. Chem. Phys., 130 (2009)

129. "Self-Assembly of Dendronized Polymers", with J. Das et al, J. Phys. Chem. B, 113, 13768 (2009)

130. "Efficient stochastic simulation of reaction-diffusion processes via direct compilation", with M Lis et al, Bioinformatics, 25, 289 (2009)

131. "Thymic Selection of T-Cell Receptors as an Extreme Value Problem", with A. Kosmrlj et al, Phys. Rev. Lett., 103 (2009)

132. "The impact of negative selection on thymocyte migration in the medulla", with M. LeBorgne et al, Nature Immunology, 10, 823 (2009)

133. "Stochastic bimodalities in deterministically monostable reversible chemical networks due to network topology reduction", with M. Artomov et al, J. Chem. Phys., 131 (2009)

134. "Molecular Origin and Functional Consequences of Digital Signaling and Hysteresis During Ras Activation in Lymphocytes", with J. Das et al, Science Signaling, 2 (2009)

135. "Pairing computation with experimentation: a powerful coupling for understanding T cell signaling", with J. Das, Nature Reviews Immunology, 10, 59 (2010)

136. “Statistical mechanical concepts in adaptive immunity”, with Andrej Košmrlj, Ann. Rev. Phys. Chem., 61, 283 (2010)

137. “A Model for Genetic and Epigenetic Regulatory Networks Identifies Rare Pathways for Transcription Factor Induced Pluripotency”, with M. Artyomov et al., PLOS Comp. Biol., 6(5): e1000785 (2010)

138. "Seeing in Numbers", Scientist, 24 (2010)

139. "Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection", with A. Košmrlj, Nature (2010)

140. “Fast on-rates allow short dwell time ligands to activate T cells”, with C. Govern et al., Proc. Natl. Acad. Sci., 107, 8724 (2010)

141. "For T Cell Receptors, Some Breakups Might Not Last Forever", with C. Govern, Immunity, 32, 141 (2010).

142. “Only signaling modules that discriminate sharply between stimulatory and non-stimulatory inputs require basal signaling for fast cellular responses”, with M. Artyomov et al., J Chem Phys, 133 (2010)

143. "Polyreactivity increases the affinity of anti-HIV antibodies by heteroligation", with M. Nussenszweig et al., Nature, 467 (2010)

144. “CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery”, with M. Artyomov et al., Proc. Natl. Acad. Sci., 107, 16916 (2010)

145. "Understanding the structure and function of the immunological synapse", with A. Shaw et al., Cold Spring Harbor Persp. in Biol., 2 (2010)

146. "Evolving concepts of specificity in immune reactions", with H. Eisen, Proc. Natl. Acad. Sci., 107, 22373 (2010).
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    Massachusetts Institute of Technology - 2015