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Elucidating type II diabetes by linking the expression and metabolic phenotypes of hepatoma and hepatocyte cells.Plasma glucose accumulation can be the end result of a multitude of biochemical paths and mechanisms initiated by a disruption in the insulin signaling pathway. This project attempts to elucidate the relative extent of possible glucose accumulation pathways and link such pathways to the cellular transcriptional state measured by DNA microarrays. People: |
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