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Methods for Intracellular Flux Determination


Intracellular fluxes are a fundamental determinant of cell physiology and a necessary parameter in elucidating flux control and targets for genetic modification. Fluxes are determined by material balancing, NMR fine spectra analysis and GC-MS measurements. Issues of observability, solution uniqueness, and measurement redundancy need to be addressed.

People:

  • Professor Joanne K. Kelleher
  • Matthew S. Wong
  • Maciek Antoniewicz
  • Giovanna Casagrande
  • Saliya S. Silva
  • Dr. Kohsuke Adachi

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