ban_1.gif
ban_2.jpg
Home
News
People
Research
Publications
Software
Courses
Data Sets
Opportunities
changing picture

Publications

Books
  1. Gregory N. Stephanopoulos, Aristos A. Aristidou and Jens Nielsen; Metabolic Engineering : Principles and Methodologies; Academic Press; October 2, 1998 (725 pages).

Papers
    2005
    		 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 Pre-'95


  1. Hal Alper, Curt Fischer, Elke Nevoigt, and Gregory Stephanopoulos, (2005): Tuning genetic control through promoter engineering. PNAS. 102 (36), 12678-12683.

  2. R. Michael Raab, John Bullen Jr., Joanne Kelleher, Christos Mantzoros, and Gregory Stephanopoulos, (2005): Regulation of Mouse Hepatic Genes in Response to Diet Induced Obesity, Insulin Resistance and Fasting. Nutrition & Metabolism, (in press, 2005).

  3. R. Michael Raab, Keith Tyo, and Gregory Stephanopoulos, (2005): Metabolic Engineering. Advances in Biochemical Engineering/ Biotechnology, Springer-Verlag GmbH, 2005; Volume 100:1-16.

  4. Hal Alper, Kohei Miyaoku, and Gregory Stephanopoulos, (2005): Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets. Nat Biotechnology. 23(5), 612 - 616.

  5. Hal Alper, Yong-Su Jin, J. Moxley, and Gregory Stephanopoulos, (2005): Identifying gene targets for the metabolic engineering of Escherichia coli. Metab Eng. 7(3),155-164.


    2005
    2004
    		 2003 2002 2001 2000 1999 1998 1997 1996 1995 Pre-'95


  6. Gregory Stephanopoulos, Hal Alper, and J. Moxley, (2004): Exploiting biological complexity for strain improvement through Systems Biology. Nat. Biotechnology. 22(10), pp. 1261-7.

  7. Hal Alper, and Gregory Stephanopoulos, (2004): Metabolic engineering challenges in the post-genomic era. Chemical Engineering Science, Vol. 59(22-23), Nov-Dec 2004; pp. 5009-5017.

  8. R. Michael Raab and Gregory Stephanopoulos, (2004): Dynamics of Gene Silencing by RNA Interference. Biotechnology & Bioengineering, Vol. 88, Issue 1, Oct 5th 2004; pp. 121-132.

  9. Hyuntae Yoo, Gregory Stephanopoulos and Joanne K. Kelleher, (2004): Quantifying carbon sources for de novo lipogenesis in wild-type and IRS-1 knockout brown adipocytes. J. Lipid Res., Vol. 45, 2004; pp. 1324-1332.

  10. William A. Schmitt Jr., R. Michael Raab, and Gregory Stephanopoulos, (2004): Elucidation of gene interaction networks through time-lagged correlation analysis of transcriptional data. Genome Research, 14(8), pp. 1654-63; Aug 2004.

  11. Gyoo Yeol Jung and Gregory Stephanopoulos; (2004): A Functional Protein Chip for Pathway Optimization and in Vitro Metabolic Engineering. Science Volume 304, Number 5669; 428-431 (16 April 2004).

  12. Kyongbum Lee, Daehee Hwang, Tadaaki Yokoyama, George Stephanopoulos, Gregory N. Stephanopoulos and Martin L. Yarmush, (2004): Identification of optimal classification functions for biological sample and state discrimination from metabolic profiling data. Bioinformatics, Vol. 20, No. 6, April 2004; pp. 959-969.

  13. Matthew S. Wong, R. Michael Raab, Isidore Rigoutsos, Gregory N. Stephanopoulos, and Joanne K. Kelleher; (2004): Metabolic and transcriptional patterns accompanying glutamine depletion and repletion in mouse hepatoma cells: A model for Physiological Regulatory Networks. Physiol. Genomics 16: 247-255, january 2004.


    2005 2004
    2003
    		 2002 2001 2000 1999 1998 1997 1996 1995 Pre-'95


  14. Fernando Dangond, Daehee Hwang, Sandra Camelo, Piera Pasinelli, Matthew P. Frosch, Gregory Stephanopoulos, George Stephanopoulos, Robert H. Brown, Jr. and Steven R. Gullans, (2003): Molecular signature of late-stage human ALS revealed by expression profiling of postmortem spinal cord gray matter. Physiological Genomics, Vol. 16, Jan 2004; pp. 229-239.

  15. Daehee Hwang, Ilias Alevizos, William A. Schmitt, Jatin Misra, Hiroe Ohyama, Randy Todd, Mamatha Mahadevappa, Janet A. Warrington, George Stephanopoulos, David T. Wong and Gregory Stephanopoulos, (2003): Genomic dissection for characterization of cancerous oral epithelium tissues using transcription profiling. Oral Oncology, Vol. 39, No. 3, April 2003; pp. 259-268.

  16. Christina Chan, Daehee Hwang, Gregory N. Stephanopoulos, Martin L. Yarmush, and George Stephanopoulos, (2003): Application of Multivariate Analysis to Optimize Function of Cultured Hepatocytes. Biotechnol. Prog., 19(2), 2003; pp. 580-598.

  17. Schmitt, W., K. Jensen, and G. Stephanopoulos, (2002): Systems Bioengineering Challenges in Post-genomic Biological Research. Computers and Chemical Engineering.


    2005 2004 2003
    2002
    		 2001 2000 1999 1998 1997 1996 1995 Pre-'95


  18. Hwang, D., W. Schmitt, Geo. Stephanopoulos and Gr. Stephanopoulos, (2002): Determination of minimum sample size and discriminatory expression patterns in microarray data. Bioinformatics, Vol. 18, No. 9, Sept. 2002; pp. 1184-1193.

  19. Stephanopolous, Gr., D. Hwang, W. Schmitt, J. Misra and Geo. Stephanopoulos, (2002): Mapping physiological states from microarray expression measurements. Bioinformatics, Vol. 18, No. 8, August 2002; pp. 1054-1063.

  20. Jatin Misra, William Schmitt, Daehee Hwang, Li-Li Hsiao, Steve Gullans, George Stephanopoulos, and Gregory Stephanopoulos, (2002): Interactive Exploration of Microarray Gene Expression Patterns in a Reduced Dimensional Space. Genome Research, Vol. 12, Issue 7, July 2002; pp. 1112-1120.

  21. Gill RT, Katsoulakis E, Schmitt W, Taroncher-Oldenburg G, Misra J, and Stephanopoulos G.; (2002): Genome-Wide Dynamic Transcriptional Profiling of the Light-to-Dark Transition in Synechocystis Sp. Strain PCC 6803. J. Bacteriology, 2002, Jul; 184(13): 3671-81.

  22. R. T. Gill, S. Wildt, Y-T. Yang, S. Ziesman, and G. Stephanopoulos, (2002): Genome wide screening for trait conferring genes using DNA micro-arrays. PNAS, vol. 99, no. 10, 7033-7038; May 14, 2002

  23. Daniel E. Stafford, Kurt S. Yanagimachi, Philip A. Lessard, Sushil K. Rijhwani, Anthony J. Sinskey, and G. Stephanopoulos, (2002): Optimizing bioconversion pathways through systems analysis and metabolic engineering. PNAS, vol. 99, no. 4, 1801-1806; February 19, 2002


    2005 2004 2003 2002
    2001
    		 2000 1999 1998 1997 1996 1995 Pre-'95


  24. Kurt S. Yanagimachi, Daniel E. Stafford, Annette F. Dexter, Anthony J. Sinskey, Stephen Drew and Gregory Stephanopoulos, (2001): Application of radiolabeled tracers to biocatalytic flux analysis. Eur. J. Biochem., Vol. 268, Issue 18, Sept. 2001; pp. 4950-4960.

  25. Geo. Stephanopoulos, D. Hwang, J. Misra, W.A. Schmitt, and Gr. Stephanopoulos, (2001): Functional Genomics and Systems Engineering. Proceedings of 6th IFAC Symposium on DYCOPS, Korea, June 4-6, 2001.

  26. Stephanopolous, Gr., and W. A. Schmitt, (2001): Systems Biology: an Emerging Theme in Biological Research. European Symposium on Computer Aided Process Engineering - 11, Int'l Conf., Copenhagen, May 27-30, 2001.

  27. R. Robert Balcarcel and G. Stephanopoulos, (2001): Rapamycin reduces hybridoma cell death and enhances monoclonal antibody production. Biotechnology & Bioengineering, Volume 76, Issue 1, 2001.


    2005 2004 2003 2002 2001
    2000
    		 1999 1998 1997 1996 1995 Pre-'95


  28. M. Reinecke and G. Stephanopoulos, (2000): Flow Injection Analysis for Simultaneous Quantification of Prolactin Concentration and Glycosylation Macroheterogeneity in Cell Culture Samples. Cytotechnology, Vol. 34(3), November 2000; pp. 237-242.

  29. Stafford DE, Yanagimachi KS, and Stephanopoulos G., (2001): Metabolic engineering of indene bioconversion in Rhodococcus sp. Advances in Biochemical Engineering/Biotechnology, Vol. 73; pp. 85-101.

  30. G. Stephanopoulos, "Bioinformatics and Metabolic Engineering," Forward article of special issue on Bioinformatics, Metabolic Engineering, 2: 157-158 (2000).

  31. G. Taroncher-Oldenburg and G. Stephanopoulos, "Metabolic engineering of biodegradable plastic production by cyanobacteria: Model studies in Synechocystis sp. PCC 6803," Proceedings 18th Symposium on Energy Eng'g Sciences, Argonne Nat'l Lab, May 16,17, pp. 239-246 (2000).

  32. G. Stephanopoulos and R. Gill, "After a decade of progress, an expanded role for metabolic engineering," Advances in Biochemical Engineering, (in press) (2000).

  33. R.T. Kamimura, S. Bicciato, H. Shimizu, J. Alford and G. Stephanopoulos, " Mining of biological data II: Assessing data structure and class homogeneity by cluster analysis," Metabolic Engineering, 2: 228-238 (2000).

  34. R. T. Kamimura, S. Bicciato, H. Shimizu, J. Alford and G. Stephanopoulos, "Mining of biological data I: Identifying discriminating features via mean hypothesis testing," Metabolic Engineering, 2: 218-227 (2000).

  35. Maria I. Klapa and Gregory Stephanopoulos, "Metabolic flux analysis," chapter 3 in Bioreaction Engineering, Modeling and Control, K. Schugerl and K.H. Bellgardt (eds.), pp: 106-122, Springer, Berlin-Heidelberg-New York, (2000).

  36. Maria I. Klapa and G. Stephanopoulos, "Metabolic Engineering: A framework for the integration of genomic and physiological data," in NMR in Biotechnology: Theory and Applications, pp. 453-477, Barbotin/Portais (eds.), Horizon Scientific Press, UK (2000).

  37. B.D. Follstad, D.I.C. Wang and G. Stephanopoulos, "Mitochondrial membrane potential differentiates cells resistant to apoptosis in hybridoma cultures," European Journal of Biochemistry, 267: 1-8, (2000).

  38. B.D. Follstad, D.I.C. Wang and G. Stephanopoulos, "Hybridomas with high mitochondrial membrane potential yield high viability in fed-batch cultures," (submitted) (2000).

  39. D.E. Stafford, P.A. Lessard, A.J. Sinskey and G. Stephanopoulos, "Metabolic engineering of indandiol synthesis in Rhodococcus: II. Selectivity optimization by genetic and culture optimization," (submitted) (2000).

  40. K.S. Yanagimachi, D.E. Stafford, S.K. Rijhwani, B.C. Buckland, A.J. Sinskey and G. Stephanopoulos, "Metabolic engineering of indandiol synthesis in Rhodococcus: I. Mutant isolation and characterization in continuous cultures," (submitted) (2000).

  41. G. Taroncher-Oldenburg and G. Stephanopoulos, "Targeted, PCR-based gene disruption in cyanobacteria: Inactivation of the polyhydroxyalkanoic acid synthase genes in Synechocystis sp. PCC6803," Applied Microbiol. & Biotechnology, 54: 677-680 (2000).

  42. G.B. Nyberg, G. Stephanopoulos, J. Zhang, and D.I.C. Wang, "The Influence of Nucleotide Sugars on Recombinant g-IFM Glycosylation in CHO Cells," (submitted) (2000).

  43. K. Lee, F. Berthiaume, G. Stephanopoulos, D.M. Yarmush and M.L. Yarmush, "Metabolic flux analysis of postburn hepatic hypermetabolism," Metabolic Engineering, 2: 312-327 (2000).

  44. Gaspar Taroncher-Oldenburg, Koren Nishina and G. Stephanopoulos, "Identification and analysis of the polyhydroxyalkanoate specific b-ketothiolase and acetoacetyl-CoA reductase genes in the cyanobacterium Synechocystis sp. PCC6803," Applied Env. Microbiology, 66: 4440-4448 (2000).

  45. A. Sanfeliu, J. Chung, and G. Stephanopoulos, "Effect of insulin stimulation on the proliferation and death of CHO Cells," Biotechnol. & Bioeng., 70: 421-427, (2000).

  46. G. Taroncher-Oldenburg, R. T. Gill and G. Stephanopoulos, G. "Green biosynthesis of polyhydroxyalkanoates: Engineering of cyanobacteria for biopolymer production," in: Proceedings 4th annual green chemistry and engineering conference, ACS, Washington, D.C., pp. 61-4 (2000).

  47. J.V. Shanks and G. Stephanopoulos (eds.), Special issue on Biochemical Engineering, Current Opinion in Biotechnology, 11: 169-214, (2000).

  48. G.B. Nyberg, R.R. Balcarcel, B.D. Follstad, G. Stephanopoulos, and D.I.C. Wang, "Metabolic Effects on Recombinant g -interfernon Glycosylation in Continuous Culture of CHO Cells," Biotechnol. & Bioeng., 62: 336-347 (1999), also in IBM J. Res. Develp. 44: 770-781, (2000).


    2005 2004 2003 2002 2001 2000
    1999
    		 1998 1997 1996 1995 Pre-'95


  49. E. M. T. El-mansi and G. Stephanopoulos, "Flux control analysis: Basic principles and industrial applications," chapter in Fermentation Microbiology and Biotechnology, pp. 179-196, (1999).

  50. M. Koffas, C. Roberge, K. Lee and G. Stephanopoulos, "Metabolic Engineering," Annual Reviews of Biomedical Engineering," 1: 535-557, (1999).

  51. S.L. Treadway, K. Yanagimachi, P.A. Lessard, G. Stephanopoulos and A.J. Sinskey, "Characterization of the nidC diol dehydrogenase from Rhodococcus strain I24," (submitted) (1999).

  52. K. Lee, F. Berthiaume, G. Stephanopoulos and M.L. Yarmush, "Metabolic flux analysis: A powerful tool for monitoring tissue function," Tissue Eng., 5: 347-368 (1999).

  53. S.P. Walton, G. Stephanopoulos, M.L. Yarmush and C.M. Roth, "Prediction of antisense oligonucleotide binding affinity to a structured RNA target," Biotechnol. & Bioeng., 65:1-9, (1999).

  54. G. Stephanopoulos, "Emerging directions in computer applications to biotechnology: Upgrading the information content of biological data," Annual Reviews in Control, 23: 61-69, (1999).

  55. J. Goswami, A.J. Sinskey, H. Steller, G. Stephanopoulos, and D.I.C. Wang, "Apoptosis in Batch Cultures of Chinese Hamster Ovary Cells," Biotechn. & Bioeng., 62, pp. 632-640, (1999).

  56. S.L. Treadway, K. Yanagimachi, E. Lankenau, P.A. Lessard, G. Stephanopoulos, and A.J. Sinskey, "Isolation and Characterization of Indene Metabolism Genes from Rhodococcus strain I24," Applied Microbiol. and Biotech. 51: 786-793, (1999).

  57. B. Follstad, R. Balcarcel, D.I.C. Wang, and G. Stephanopoulos, "Metabolic Flux Analysis of Hybridoma Continuous Culture Steady State Multiplicity," Biotechnol. & Bioeng. 63: 675-683 (1999).

  58. A. Sanfeliu and G. Stephanopoulos, "Effect of Glutamine Limitation on the Death of Attached CHO Cells," Biotechnol. & Bioeng., 64: 46-53 (1999).

  59. G.B. Nyberg, R.R. Balcarcel, B.D. Follstad, G. Stephanopoulos, and D.I.C. Wang, "Metabolism of Peptide Aminoacids by CHO Cells Grown in Complex Media," Biotechnol. & Bioeng., 62: 324-335 (1999). 153.G.B.

  60. C.A. Shaw-Reid, M.M. McCormick, A.J. Sinskey, and G. Stephanopoulos, "Flux through the Tetrahydrodipicolinate Succinylase Pathway is Dispensable for Lysine Productions in C. Glutamicum," Appl. Microb. & Biotech., 51: 325-333 (1999).

  61. G. Stephanopoulos, "Metabolic Fluxes and Metabolic Engineering," Metabolic Engineering, 1: 1-10 (1999).

  62. T.W. Simpson, B.D. Follstad, and G. Stephanopoulos, "Analysis of Pathway Structure of Metabolic Networks," J. Biotechn., 71: 207-223, (1999).

  63. S. M. Park, M. I. Klapa, A. J. Sinskey and G. Stephanopoulos, "Metabolite and Isotopomer Balancing in the Analysis of Metabolic Cycles: II. Applications", Biotechnol. & Bioeng., 62: 392-401, (1999).

  64. M. I. Klapa, S. M. Park, A. J. Sinskey and G. Stephanopoulos, "Metabolite and Isotopomer Balancing in the Analysis of Metabolic Cycles: I. Theory", Biotechnol. & Bioeng., 62: 375-391, (1999).


    2005 2004 2003 2002 2001 2000 1999
    1998
    		 1997 1996 1995 Pre-'95

  65. M. Koffas, R. Ramamoorthi, W. Pine, A.J. Sinskey, and G. Stephanopoulos, "Sequence of the Pyruvate Carboxylase Gene in C. glutamicum," Appl. Microb. & Biotech., 50: 346-352 (1998).

  66. S. Bicciato, R. Kamimura, H. Shimizu, and G. Stephanopoulos, "Quantification of Data Clusters for Bioprocess Performance Classification via Artificial Intelligence," Proceedings, IFAC Conf. Comp. Appl. to Biotech., Osaka, May 31-June 4, (1998).

  67. G. Stephanopoulos, "Emerging directions to computer applications to biotechnology: Upgrading the information content of biological data," Proceedings, IFAC Conf. Comp. Appl. to Biotech., Osaka, May 31-June 4, (1998).

  68. B. Follstad and G. Stephanopoulos, "Isotope Label Distribution in the Pentose Phosphate Pathway", Eur. J. Biochem. 252 (3): 360-372 (1998).

  69. T. W. Simpson, H. Shimizu and G. Stephanopoulos, "Experimental Determination of Group Flux Control Coefficients in Metabolic Networks", Biotechnol. & Bioeng., 58: 149-153 (1998).


    2005 2004 2003 2002 2001 2000 1999 1998
    1997
    		 1996 1995 Pre-'95


  70. S. M. Park, C. Shaw-Reid, A. J. Sinskey and G. Stephanopoulos, "Elucidation of Anaplerotic Pathways in Corynebacterium glutamicum via C13-NMR Spectroscopy and GC-MS", Applied Microbiol. & Biotechn., 47: 430 - 440 (1997).

  71. J. Chung, C. Zabel, A. J. Sinskey and G. Stephanopoulos, "Extension of Sp2/0 Hybridoma Cell Viability Through IL-6 Supplementation", Biotechnol. & Bioeng., 55: 439 - 446 (1997).

  72. J. Chung, A. J. Sinskey and G. Stephanopoulos, "Growth Factor and BCL-2 Mediated Survival During the Abortive Proliferation of a Hybridoma Cell Line", Biotechnol. & Bioeng., 57: 164-171 (1997).

  73. T. W. Simpson and G. Stephanopoulos, "Flux Amplification in Complex Metabolic Networks", Chem. Eng. Science, 52: 2607 - 2627 (1997).

  74. S. M. Park, A. J. Sinskey and G. Stephanopoulos, "Metabolic and Physiological Studies of Corynebacterium glutamicum mutants", Biotechnol. & Bioeng., 55: 864-879 (1997).

  75. G. Stephanopoulos, G. Locher, M. J. Duff, R. Kamimura and Geo. Stephanopoulos, "Fermentation Database Mining by Pattern Recognition," Biotechnol. & Bioeng., 53: 443-452 (1997).

  76. G. E. Grampp, H. F. Lodish and G. Stephanopoulos, "Processing and Secretion of Insulin Related Peptides in an Insulinoma Cell Line", Biotechnol. & Bioeng., 53: 283-289 (1997).

  77. G. E. Grampp, H. F. Lodish and G. Stephanopoulos, "Analysis of Secretory Dynamics and Development of Media for the Controlled Secretion of Insulin-Related Peptides from *TC-3 Insulinoma Cells", Biotechnol. & Bioeng., 53: 274-282 (1997).


    2005 2004 2003 2002 2001 2000 1999 1998 1997
    1996
    		 1995 Pre-'95


  78. G. Stephanopoulos, "Kinetic Analysis of Complex Metabolic Networks", Proceedings 14th Symposium on Energy Eng'g Sciences, Argonne Nat'l Lab, May 15, 16 (1996).

  79. G. Locher, B. Bakshi, Geo. Stephanopoulos, G. Stephanopoulos and K. Schgerl, "Ein Ansatz zur Automatischen Umwandlung von Rohdatten in Regeln Teil 2: Eine Fallstudie", Automatisierungstechnik, 44: 138-145 (1996).

  80. G. Locher, B. Bakshi, Geo. Stephanopoulos, G. Stephanopoulos and K. Schgerl, "Ein Ansatz zur Automatischen Umwandlung von Rohdatten in Regeln", Automatisierungstechnik, 44: 61-70 (1996).

  81. G. Stephanopoulos, G. Locher and M. Duff, "Pattern Recognition Methods for Fermentation Database Mining", IFAC Proceedings, CAB6, Garmish, Germany (1996).

  82. R. Kamimura, K. Konstantinov and G. Stephanopoulos, "KBS, ANN and Pattern Recognition Applications in Fermentation Processes", Current Opinion in Biotechnology, 7: 231-234 (1996).

  83. M. Shelikoff, A.J. Sinskey and G. Stephanopoulos, "A Modeling Framework for the Study of Protein Glycosylation," Biotechnol. & Bioeng., 50: 73-90 (1996).

  84. J. Chung and G. Stephanopoulos, "On Physiological Multiplicity and Population Heterogeneity of Biological Systems," Chemical Eng. Science, 51: 1509-1521 (1996).

  85. G. Stephanopoulos, M. Applegate, R. Singhvi, S. Park and M.F. Stephanopoulos, "Cell Culturing Apparatus and Method Employing a Macroporous Support," U.S. Patent No. 5,510,262 (1996).

  86. G. E. Grampp, M. A. Applegate and G. Stephanopoulos, "Cyclic Operation of a Single-Pass Animal Cell Bioreactor for Controlled Secretion of an Endocrine Hormone", Biotech. Progress, 12: 837-846 (1996).


    2005 2004 2003 2002 2001 2000 1999 1998 1997 1996
    1995
    		 Pre-'95


  87. K. Chen, G. Stephanopoulos, A. J. Sinskey and H. F. Lodish, "Regulated Secretion of Prolactin by the Mouse Insulinoma Cell Line *TC3", Bio/Technology, 13: 1191-1197 (1995).

  88. T.W. Simpson, G.E. Colon, and G. Stephanopoulos, "Two Paradigms of Metabolic Engineering Applied to Amino Acid Biosynthesis". Biochem. Soc. Transactions, 23: 379-385 (1995).

  89. J.D. Chung and G. Stephanopoulos, "Flow Cytometric Study of Differentiating Cultures of Bacillus subtilis," Cytometry 20: 324-333 (1995).

  90. C. Zupke, A. J. Sinskey and G. Stephanopoulos, "Intracellular Flux Analysis Applied to the Effect of Dissolved Oxygen on Hybridomas," Appl. Microbiol. & Biotechn., 44: 27-36 (1995).

  91. J.D. Chung and G. Stephanopoulos, "Studies of Transcriptional State Heterogeneity in Sporulating Cultures of Bacillus subtilis," Biotechnol. & Bioeng. 47: 234-242 (1995).

  92. G. ColĒn, T.T. Nguyen, S.M. Jetten, A.J. Sinskey, and Gregory Stephanopoulos, "Production of Isoleucine by Overexpression of IlvA in a Corynebacterium lactofermentum threonine producer," Appl. Microb. & Biotech., 43: 482-488 (1995).

  93. C. Zupke and G. Stephanopoulos, "Intracellular Flux Analysis in Hybridomas Using Mass Balances and in vitro C13 NMR," Biotechnology & Bioengineering, 45: 292-303 (1995).

  94. G.E. ColĒn, M.S.M. Jetten, T.T. Nguyen, M.E. Gubler, M.T. Follettie, A.J. Sinskey and G. Stephanopoulos, "Effect of Inducible thrB Expression on Amino Acid Production in Corynebacterium lactofermentum 21799," Applied & Environ. Microbiology, 61: 74-78 (1995).


    2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995
    Pre-'95


  95. J. Chung, G. Stephanopoulos, K. Ireton and A.D. Grossman, "Gene expression in Single Cells of Bacillus subtilis: Evidence that a Threshold Level of Phosphorylated SpoOA Transcription Factor is needed for the Initiation of Sporulation," J. Bacteriology, 176, pp. 1977-1984 (1994).
  96. R. Singhvi, A. Kumar, G.M. Whitesides, D. Ingber, G. Stephanopoulos and D.I.C. Wang, "Engineering Cell Shape and Function," Science, 264, pp. 696-699 (1994).
  97. R. Singhvi, G. Stephanopoulos and D.I.C. Wang, "Effects of Substratum Morphology on Cell Physiology," Biotechnol. & Bioengin., 43, pp. 764-771 (1994).
  98. M. Gubler, S.M. Park, A.J. Sinskey and G. Stephanopoulos, "Effects of Phosphoenol Pyruvate Carboxylase Deficiency on Metabolism and Lysine Production in Corynebacterium glutamicum," Appl. Microb. and Biotech., 40, pp. 857-868, (1994).
  99. B. Bakshi, G. Locher, G. Stephanopoulos, and Geo. Stephanopoulos, "Analysis of Data for Evaluation, Diagnosis and Control of Batch Operations," J. of Process Control, 4, pp. 175-194 (1994).
  100. G. Stephanopoulos, "Metabolic Engineering," Current Opinion in Biotechnology, 5, pp. 196-200 (1994).
  101. M. Shelikoff, A.J. Sinskey, and G. Stephanopoulos, "The Effect of Protein Synthesis Inhibitors on the Glycosylation Site Occupancy of Recombinant Human Prolactin," Cytotechnology, 15, pp. 195-208 (1994).
  102. C. Zupke and G. Stephanopoulos, "Modeling of Isotope Distribution and Intracellular Fluxes in Metabolic Networks Using Atom Mapping Matrices," Biotechnology Progress, 10, pp. 489-498 (1994).
  103. G. Locher, B. Bakshi, George Stephanopoulos, Gregory Stephanopoulos and K. Schgerl, "Database Mining (in German)," Chemical Ing. Tech., 66, Number 4, pp. 541-543 (1994).
  104. J.J. Vallino and G. Stephanopoulos, "Carbon Flux Distributions at the Pyruvate Branch Point in C. glutamicum during Lysine Overproduction," Biotechnology Progress 10, pp. 327-334 (1994).
  105. J.J. Vallino and G. Stephanopoulos, "Carbon Flux Distributions at the Glucose-6 phosphate Branch Point in Corynebacterium glutamicum during Lysine Overproduction," Biotechnology Progress 10, pp. 320-326 (1994).
  106. R. Singhvi, A. Kumar, D. Ingber, G. Whitesides, D.I.C. Wang and G. Stephanopoulos, "Method of Formation of Microstructured Patterns on Plates for Adhesion of Cells and Other Biological Materials, Devices and Uses There for," U.S. Patent (filed) (1993).
  107. G. Stephanopoulos (ed.), "Bioprocessing," Vol. 3 of Biotechnology, H.J. Rehm, G. Reed, A. Puhler, P. Stadler (series eds.), VCH, Weinheim (1993).
  108. G. Stephanopoulos and A.J. Sinskey, "Metabolic Engineering: Issues and Methodologies," Trends in Biotechnology, Vol. 11, pp. 392-396 (1993).
  109. S. Park and G. Stephanopoulos, "Packed Bed Bioreactor with Porous Ceramic Beads for Animal Cell Culture," Biotechnology & Bioengineering, 41, pp. 25-34, (1993).
  110. J.J. Vallino and G. Stephanopoulos, "Metabolic Flux Distributions in Corynebacterium glutamicum During Growth and Lysine Overproduction," Biotechnology & Bioengineering, 41, pp. 633-646 (1993).
  111. G. Stephanopoulos, K. Konstantinov, U. Saner and T. Yoshida, "Fermentation Data Analysis for Diagnosis and Control," Chapter 15, pp. 355-400, in Bioprocessing, Vol. 3, G. Stephanopoulos (ed.), VCH Weinheim (1993).
  112. M.N. Karim and G. Stephanopoulos (eds.), "Modelling and Control of Biotechnical Processes," IFAC Symposia Series No. 10, Proceedings of the 5th Int. Conf. of Computer App. in Ferm. Tech., Keystone, CO, 29 March - 2 April 1992, Pergamon Press (1992).
  113. S.M. Park and G. Stephanopoulos, "Applications of Metabolic Engineering to Metabolite Overproduction," Proc. of 1st Spanish-Portuguese Congress on Biotechnology, Sept. 14-18, Santiago de Compostella, Spain (1992).
  114. S.M. Park and G. Stephanopoulos, "Regulation and Control of Metabolic Pathways," Proceedings from Int'l Symposium on Information Sciences, July 11-15, Kyushu, Japan (1992).
  115. U. Saner and G. Stephanopoulos, "Application of Pattern Recognition Techniques to Fermentation Data Analysis," pp. 123-128 in Modeling and Control of Biotechnical Processes 1992, M.N. Karim and G. Stephanopoulos (eds.), IFAC Symposia Series No. 10, Pergamon Press, Oxford, (1992).
  116. G. Stephanopoulos, "Fermentation Diagnosis and Control: Balancing Old Tools with New Concepts," 9th Int'l Biotechnology Symposium, ACS Series, Crystal City, VA, August (1992).
  117. G. Grampp and G. Stephanopoulos, "Development and Scale-up of Controlled Secretion Processes for Improved Product Recovery in Animal Cell Culture," Biochem. Eng. VII, Ann. N.Y. Academy of Sci., pp. 81-93, (1992).
  118. T. Chattaway, A.L. Demain and G. Stephanopoulos, "Use of Various Measurements for Biomass Estimation," Biotechnology Progress, 8, pp. 81-84, (1992).
  119. R.D. Kiss and G. Stephanopoulos, "Culture Instability of Auxotrophic Aminoacid Producers," Biotechnology & Bioengineering, 40, pp. 75-85, (1992).
  120. M.A. Applegate and G. Stephanopoulos, "Development of a Single-Pass Ceramic Matrix Bioreactor for Large-Scale Mammalian Cell Culture," Biotechnology & Bioengineering, 40, pp. 1056-1068, (1992).
  121. R.D. Kiss and Gregory Stephanopoulos, "Metabolic Characterization of a L-Lysine Producing Strain by Continuous Culture," Biotechnology & Bioengineering, 39, pp. 565-574, (1992).
  122. M. Mavrovouniotis, George Stephanopoulos and Gregory Stephanopoulos, "Synthesis of Biochemical Production Routes," Computers in Chemical Engin'g., 16, pp. 605-619 (1992).
  123. G.E. Grampp, A. Sambanis and G. Stephanopoulos, "Use of Regulated Secretion in Protein Production from Animal Cells: An Overview," Advances in Biochemical Engineering/Biotechnology, Vol. 46, pp. 35-62 (1992).
  124. M.J. Kennedy, M.S. Thakur, D.I.C. Wang and G. Stephanopoulos, "Estimating Cell Concentration in the Presence of Suspended Solids: A Light Scatter Technique," Biotechnology & Bioengineering, 40, pp. 875-888, (1992).
  125. M.J. Kennedy, M.S. Thakur, D.I.C. Wang and G. Stephanopoulos, "Techniques for the Estimation of Cell Concentration in the Presence of Suspended Solids. A Review," Biotechnology Progress, 8, pp. 375-381 (1992).
  126. G. Stephanopoulos and R.D. Kiss, "Bioreactor Monitoring and Control," Encyclopedia of Microbiology, J. Lederberg (ed.), Academic Press, Inc., vol. 1, pp. 351-362 (1992).
  127. R. Singhvi, G. Stephanopoulos and D.I.C. Wang, "Effect of Substratum Morphology on Animal Cell Adhesion and Behavior," Proceedings MRS Conference, Boston, Nov. (1991).
  128. Y. Shoham, G. Stephanopoulos and A.L. Demain, "Effects of the á-Lactamase Gene and Orientation of the Kanamycin Resistance Gene in Plasmids pCED3 on the Growth of Bacillis subtilis," J. Ferm. Bioeng., 72, pp. 244-248, (1991).
  129. R.D. Kiss and G. Stephanopoulos, "Metabolic Activity Control of L-Lysine Fermentation by Restrained Growth Fed-Batch Strategies," Biotechnology Progress, 7, pp. 501-509, (1991).
  130. G. Stephanopoulos and J.J. Vallino, "Network Rigidity and Metabolic Engineering in Metabolite Overproduction," Science, 252, pp. 1675-1681 (1991).
  131. A. Sambanis, G. Stephanopoulos and H.F. Lodish, "A Model of Secretory Protein Trafficking in Recombinant AtT-20 Cells," Biotechnology & Bioengineering, 38, pp. 280-295 (1991).
  132. Gregory Stephanopoulos and Seujeung Park, "Bioreactor State Estimation," Chapter 2.7 of Vol. 4, pp. 225-249 "Measuring, Modeling, and Control," of "Biotechnology-A Multi-volume Comprehensive Treatise," H.J. Rehm and G. Reed (eds.), Verlagsgesellschaft (1991).
  133. M. Mavrovouniotis, George Stephanopoulos and Gregory Stephanopoulos, "Estimation of Upper Bounds for the Rates of Enzymatic Reactions," Chem. Eng. Commun., 93, pp. 211-236 (1990).
  134. J.J. Vallino and Gregory Stephanopoulos, "Intracellular Flux Analysis As Means of Identifying Limiting Nodes in Amino Acid Fermentations," Proc. 5th European Congress on Biotechnology, Copenhagen, July 8-13 (1990).
  135. M. Mavrovouniotis, George Stephanopoulos and Gregory Stephanopoulos, "Computer-Aided Synthesis of Biochemical Pathways," Biotechnol. & Bioengineering, 36, pp. 1119-1132 (1990).
  136. G. Stephanopoulos and R. Singhvi, "Accomplishments in Biochemical Engineering," chapter in Biotechnology: Science, Education & Commercialization, I.K. Vasil (ed.), Elsevier (1990).
  137. A. Sambanis, G. Stephanopoulos and H.F. Lodish, "Multiple Episodes of Induced Secretion of Human Growth Hormone from Recombinant AtT-20 Cells," Cytotechnology, 4, pp. 111-119 (1990).
  138. M. Kennedy, D.I.C. Wang and G. Stephanopoulos, "Measurements of Solid Particle Concentration in Presence of a Second Particle Type," U.S. Patent No. 4,969,741 (1990).
  139. B.J.M. Hannoun and G. Stephanopoulos, "Growth and Fermentation Model for Alginate-Entrapped Saccharomyces cerevisiae," Biotechnology Progress, 6, pp. 349-356 (1990).
  140. B.J.M. Hannoun and G. Stephanopoulos, "Intrinsic Growth and Fermentation Rates of Alginate-Entrapped Saccharomyces cerevisiae," Biotechnology Progress, 6, pp. 341-348 (1990).
  141. R.D. Kiss, M.T. Follettie, and G. Stephanopoulos, "Quantitative Assay for Low Levels of L. Threonine in Amino Acid Fermentation Broths," Biotechnol. and Bioengin. 35, pp. 1169-1173 (1990).
  142. A. Sambanis, G. Stephanopoulos, H.F. Lodish, and A.J. Sinskey, "Use of Regulated Secretion in Protein Production from Animal Cells: A First Evaluation with the AtT-20 Model Cell Line," Biotechnol and Bioengin. 35, pp. 771-780 (1990).
  143. R. Grosz and G. Stephanopoulos, "Physiological, Biochemical and Mathematical Studies of Microaerobic Continuous Ethanol Fermentation by Saccharomyces cerevisiae. Part III," Biotechnol. and Bioengin. 36, pp. 1030-1040 (1990).
  144. R. Grosz and G. Stephanopoulos, "Physiological, Biochemical and Mathematical Studies of Microaerobic Continuous Ethanol Fermentation by Saccharomyces cerevisiae. Part II," Biotechnol. and Bioengin. 36, pp. 1020-1029 (1990).
  145. Ron Grosz and G. Stephanopoulos, "Physiological, Biochemical and Mathematical Studies of Microaerobic Continuous Ethanol Fermentation by Saccharomyces cerevisiae. Part I," Biotechnol. and Bioengin. 36, pp. 1006-1019 (1990).
  146. J.J. Vallino and G. Stephanopoulos, "Flux Determination in Cellular Bioreaction Networks. Application to Lysine Fermentations," Frontiers in Bioprocessing, S. Sikdar, M. Bier, P. Todd (eds.), pp. 205-219, CRC Press, Inc., Boca Raton, FL (1990).
  147. G. Stephanopoulos, J. Kornfield and G.E. Voecks, "Monolith Reactor Containing a Plurality of Flow Passages and Method for Carrying Out Biological Reactions," U. S. Patent No. 4,948,728 (1990).
  148. T. Chattaway and G. Stephanopoulos, "An Adaptive State Estimator for Detecting Contaminants in Bioreactors," Biotechnol. and Bioengin., 34, pp. 647-659 (1989).
  149. K.Y. San and G. Stephanopoulos, "Optimization of Fed-Batch Penicillin Fermentation. A Case of Singular Optimal Control with State Constraints," Biotechnol. and Bioeng. 34, pp. 72-78 (1989)
  150. T. Chattaway and G. Stephanopoulos, "Adaptive Estimation of Bioreactors: Monitoring Plasmid Instability," Chem. Eng. Science, 44, pp. 41-48 (1989).
  151. M. R. Hoffmann, R. G. Arnold, and Gregory Stephanopoulos, "Microbial Reduction of Iron Ore," U. S. Patent No. 4,880,740 (1989).
  152. M. Mavrovouniotis, George Stephanopoulos and Gregory Stephanopoulos, "Formal Modeling of Approximate Relations in Biochemical Systems," Biotechn. and Bioengin., 34, pp. 196-206 (1989).
  153. G. Stephanopoulos and K. Tsiveriotis, "The Effect of Intraparticle Convection on Nutrient Transport in Porous Biological Pellets," Chem. Eng. Science, 44, pp. 2031-2039, (1989).
  154. T. Chattaway and G. Stephanopoulos, "Adaptive Monitoring of Bioreactor Contamination," Proc. IV Intern. Conf. Comp. Applic. to Fermentation Technology, Cambridge, England (1988).
  155. Gregory Stephanopoulos and K. Tsiveriotis, "Toward a Systematic Method for the Generalization of Fermentation Data," Proc. IV Intern. Conf. Comp. Applic. to Fermentation Technology, Cambridge, England (1988).
  156. M. Mavrovouniotis, P. Bayol, T.K. Lam, George Stephanopoulos and Gregory Stephanopoulos, "A Group Contribution Method for the Estimation of Equilibrium Constants for Biochemical Reactions," Biotechnol. Techniques, 2, pp. 23-28 (1988).
  157. K.Y. San, G. Stephanopoulos, N.S. Wang, and E.T. Papoutsakis, "Measurement, Data Analysis, and Control of Anaerobic Digesters," Chapter 12 in Handbook on Anaerobic Fermentations, L.E. Erickson and D.Y.C. Fung (eds.) pp. 441-462, Marcel Dekker, Inc., New York (1988).
  158. G. Stephanopoulos, "Modeling Mixed Culture Interactions in Anaerobic Digestion. Application to Digester Start-Up and Control," Chapter 19 in Handbook on Anaerobic Fermentations, L.E. Erickson and D.Y.C. Fung (eds.) pp. 597-639, Marcel Dekker, Inc., New York (1988).
  159. G. Stephanopoulos and G.R. Lapidus, "Chemostat Dynamics of Plasmid-Bearing, Plasmid-Free Mixed Recombinant Cultures," Chem. Eng. Sci. 43, pp. 49-57 (1988).
  160. T. Chattaway and G. Stephanopoulos, "A New Technique for Estimation of Bioreactors: Adaptive State Observers," Proc. of Intern. Workshop on Control of Biotechnical Processes, Univ. of Newcastle, (1987).
  161. G. Stephanopoulos, "Problems and Opportunities in Bioreactor Control," Proc. 4th Mediterranean Congress of Chem. Eng., Vol. I, pp. 71-84 Barcelona, Nov. 11-13 (1987).
  162. M.L. Mavrovouniotis, George Stephanopoulos and Gregory Stephanopoulos, "A User Interface for the Design of Biochemical Pathways," Proc. of AAAI Conf., (1987)
  163. J.J. Vallino and Gregory Stephanopoulos, "Intelligent Sensors in Biotechnology; Applications for the Monitoring of Fermentations and Cellular Metabolism," Annals N.Y. Acad. Sci. 506, pp. 415-430 (1987).
  164. L.E. Erickson and G. Stephanopoulos, "Biological Reactors," chapter 12 in Chemical Reaction and Reactor Engineering, J.J. Carberry and A. Varma (eds.), pp. 779-838, Marcel Dekker, Inc., New York (1987).
  165. George Stephanopoulos and Gregory Stephanopoulos, "Artificial Intelligence in the Development and Design of Biochemical Processes," Trends in Biotechnology, 4, pp. 241-249 (1986).
  166. B.H. Davison and G. Stephanopoulos, "Coexistence of S. cerevisiae and E. coli in a Chemostat under Substrate Competition and Product Inhibition," Biotech. and Bioeng., 28, pp. 1742-1752 (1986).
  167. B.J.M. Hannoun and G. Stephanopoulos, "Diffusion Coefficients of Glucose and Ethanol in Cell-Free and Cell-Occupied Calcium Alginate Membranes," Biotech. and Bioeng., 28, pp. 829-835 (1986).
  168. G. Stephanopoulos, "A New Approach to Bioprocess Modelling," Proc. 1st IFAC Symposium on Mod. and Control of Biotechnological Processes, (1986).
  169. G. Stephanopoulos, "Application of Macroscopic Balances and Bioenergetics of Growth to the On-Line Identification of Biological Reactors," Annals N.Y. Acad. Sci., Vol. 469, Bioch. Eng. IV, pp. 332-349 (1986).
  170. B.H. Davison and G. Stephanopoulos, "Effect of pH Oscillations on a Competing Mixed Culture," Biotech. and Bioeng., 28, pp. 1127-1137 (1986).
  171. J. Kornfield and G. Stephanopoulos, "Oxygen Transfer in Membrane-Ceramic Composite Materials for Immobilized-Cell Monolithic Reactors," Biotechnology Progress, 2, pp. 98-104 (1986).
  172. A. Dalla Torre and G. Stephanopoulos, "A Simulation Study of Anaerobic Digestor Control," Biotech. and Bioeng., 28, pp. 1138-1153 (1986)
  173. A. Dalla Torre and G. Stephanopoulos, "A Mixed Culture Model of Anaerobic Digestion. Application to the Evaluation of Start-Up Procedures," Biotech. and Bioeng., 28, pp. 1106-1118 (1986)
  174. K.Y. San and G. Stephanopoulos, "The Effect of Growth Rate Delays on the Optimal Profile of Fed-Batch Reactors," Biotech. and Bioeng., 28, pp. 356-361 (1986).
  175. B.H. Davison, K.Y. San, and G. Stephanopoulos, "Stable Competitive Coexistence in a Continuous Fermentor with Size-Selective Properties, "Biotechnology Progress, 1, pp. 260-268 (1985).
  176. G. Stephanopoulos, K.Y. San, and B.H. Davison, "A Novel Bioreactor-Cell Precipitator Combination for High-Cell Density, High-Flow Continuous Fermentations," Biotechnology Progress, 1, pp. 250-259 (1985).
  177. Dorian Liepmann and G. Stephanopoulos, "A Closed Ecosystem Model: Development and Global Sensitivity Analysis," Ecological Modelling 30, pp. 13-47 (1985).
  178. Nam Sun Wang and G. Stephanopoulos, "A New Approach to Bioprocess Modelling and Identification," Biotech. and Bioeng., Symp. No. 14, pp. 635-656 (1984).
  179. G. Stephanopoulos and K.Y. San, "Application of Enhanced Sedimentation in an Integrated Fermentor Design for Simultaneous Fermentation and Cell Recycle," Proceedings 3rd European Congress on Biotechnology, Sept. 10, 1984, Vol. II, 253 (1984).
  180. K.Y. San and G. Stephanopoulos, "A Note on the Optimality Criteria for Maximum Biomass Production in a Fed-Batch Reactor," Biotech. and Bioeng., 26, pp. 1261-1264 (1984).
  181. N.S. Wang and G. Stephanopoulos, "Computer Applications to Fermentation Processes," CRC Critical Reviews in Biotech. 2, 1-103 (1984).
  182. K.Y. San and G. Stephanopoulos, "Studies on On-Line Bioreactor Identification. IV. Utilization of pH Measurements for Product Estimation," Biotech. and Bioeng., 26, 1209-1218 (1984).
  183. R. Grosz, G. Stephanopoulos, and K.Y. San, "Studies on On-Line Bioreactor Identification. III. Sensitivity Problems with Respiratory Quotient and Heat Evolution Measurements," Biotech. and Bioeng., 26, 1198-1208 (1984).
  184. K.Y. San and G. Stephanopoulos, "Studies on On-Line Bioreactor Identification. II. Numerical and Experimental Results," Biotech. and Bioeng., 26, pp. 1189-1197 (1984).
  185. G. Stephanopoulos and K.Y. San, "Studies on On-Line Bioreactor Identification. I. Theory", Biotech. and Bioeng., 26, pp. 1176-1188 (1984).
  186. N.S. Wang and G. Stephanopoulos, "Application of Macroscopic Balances to the Identification of Gross Measurement Errors," Biotech. and Bioeng., 25, pp. 2177-2208 (1983).
  187. R. Grosz and G. Stephanopoulos, "Statistical Mechanical Estimation of the Free Energy of Formation of E. coli Biomass for Use with Macroscopic Bioreactor Balances," Biotech. and Bioeng., 25, pp. 2149-2163 (1983).
  188. G. Stephanopoulos and K.Y. San, "On-Line Estimation of Time Varying Parameters. Application to Biochemical Reactors," Modeling and Control of Biotechnical Process, Proc. of 1st IFAC Workshop, A. Halme (ed.), pp. 195-200 (1983).
  189. K.Y. San and G. Stephanopoulos, "Optimal Control Policy for Substrate-Inhibited Kinetics with Enzyme Deactivation in an Isothermal CSTR," AIChE J., 29, pp. 417-424 (1983).
  190. H.W. Blanch, T. Papoutsakis, and G. Stephanopoulos, (eds.), "Foundations of Biochemical Engineering. Kinetics and Thermodynamics in Biological Systems, "papers presented at the 1982 ACS/IEC Winter Symposium on Biochemical Engineering, Jan. 17-20, 1983, Boulder, Colorado. ACS Symposium Series, 207 (1983)
  191. G. Stephanopoulos and K.Y. San, "On-Line Estimation of the State of Biochemical Reactors," ACS Symposium Series, 196, pp. 155-164 (1982).
  192. G. Stephanopoulos, "The Dynamics of Commensalism," Biotech. and Bioeng., 23, pp. 2243-2255 (1981).
  193. G. Stephanopoulos and K.Y. San, "State Estimation for Computer Control of Biochemical Reactors," Proc. of VIth Ferm. Symp., July 20-25, 1980, London, Canada, Volume I, pp. 399-406, M. Moo-Young, C.W. Robinson, C. Vezino (eds.) (1981).
  194. G. Stephanopoulos and A.G. Fredrickson," Extinction Probabilities in Microbial Predation: A Birth and Death Approach," Bulletin of Math. Biology, 43, pp. 165-181 (1981).
  195. A.G. Fredrickson and G. Stephanopoulos, "Microbial Competition," invited review, Science, 213, pp. 972-979 (1981).
  196. Gregory Stephanopoulos, "Zero Concentration Surfaces in a Cylindrical Catalyst Pellet," Chem Eng. Science, 35, pp. 2345-2349 (1980).
  197. Gregory Stephanopoulos, "Dynamics of Mixed Cultures of Microorganisms: Topological Considerations," AIChE J., 25, pp. 802-816 (1980).
  198. P. Michalopoulos, Gregory Stephanopoulos, and V.B. Pisharody, "Modeling of Traffic Flow at Signalized Links," Transp. Science, 14, pp. 9-41 (1980).
  199. P. Michalopoulos, Gregory Stephanopoulos, and George Stephanopoulos, "An Application of Shock Wave Theory to Traffic Signal Control," Trans. Research Volume 15B, pp. 35-51 (1980).
  200. Gregory Stephanopoulos and A.W. Westerberg, "Modular Design of Heat Exchanger Networks," Chem. Eng. Communications, 4, pp. 119-126 (1980).
  201. George Stephanopoulos and Gregory Stephanopoulos, "An Alternative Approach to the Optimization of Constrained Design Problems," Chem. Eng. Communications, 4, pp. 173-181 (1980).
  202. P. Michalopoulos, George Stephanopoulos, V.B. Pisharody, and Gregory Stephanopoulos, "Formation and Dissipation of Traffic Queues: Some Macro-scopic Considerations," Trans. Res. Board, pp. 81-84 (1979).
  203. Gregory Stephanopoulos, George Stephanopoulos, and P. Michalopoulos, "Real Time Control of Critical Intersections Based on Queue Dynamics", Proc. 17th IEEE Conf. on Decision and Control, San Diego, CA, pp. 1018-1024 (1979).
  204. Gregory Stephanopoulos and A.G. Fredrickson, "The Effect of Spatial Inhomogeneities on the Coexistence of Competing Microbial Populations," Biotech. and Bioeng., 21, pp. 1491-1498 (1979).
  205. Gregory Stephanopoulos, L.M. Schuelke, and George Stephanopoulos, "A Decomposition Method for the Stability Analysis of Large Microbial Systems," Theor. Pop. Biology, 16, pp. 126-143 (1979).
  206. Gregory Stephanopoulos, P. Michalopoulos, and George Stephanopoulos, "Modelling and Analysis of Traffic Queue Dynamics at Signalized Inter-sections," Transp. Res., 13A, pp. 295-307 (1979).
  207. G. Stephanopoulos and A.G. Fredrickson, "Coexistence of Photosynthetic Microorganisms with Growth Rates Depending on the Spectral Quality of Light," Bull. of Math, Biology, 41, pp. 525-542 (1979).
  208. G. Stephanopoulos, A.G. Fredrickson, and R. Aris, "The Growth of Competing Microbial Populations in a CSTR with Periodically Varying Inputs," AIChE J., 25, pp. 863-872 (1979).
  209. Gregory Stephanopoulos, R. Aris, and A.G. Fredrickson, "A Stochastic Analysis of the Growth of Competing Microbial Populations in a Continuous Biochemical Reactor," Mathematical Biosciences, 45, pp. 99-135 (1979).
  210. George Stephanopoulos and Gregory Stephanopoulos, "The Synthesis of Heat Recovery Networks for Chemical Processes," Proceedings Inter. Conf. Energy Use Management, Tucson, Arizona, pp. 123-134 (1977).

ban_2dsm.jpg
Address
Massachusetts Institute of Technology
Department of Chemical Engineering
Cambridge, MA 02139
Room 56-469 		MIT | HOME
Last Modified:
Wednesday, May 4th, 2005 - by afi.
gnswebpage-www@mit.edu 		Telephones
 office | 617.258.0398
lab | 617.253.6591
lab | 617.258.0349
lab | 617.253.6521
fax | 617.253.3122