| Requirements
for a Minor Degree in Toxicology and Environmental Health
- To satisfy the minor, complete three core subjects, one Laboratory
Core subject, and one Restricted Elective.
- The prerequisites are already required for graduation from
M.I.T.:
- 5.11: Principles of Chemical Science OR
3.091: Introduction to Solid State Chemistry
AND 7.012/3/4: Introductory Biology.
CORE SUBJECTS
Choose three from among:
BE.102
Macroepidemiology
Analyses of major causes of mortality in the US since 1900: cancer,
cardiovascular and cerebrovascular diseases, diabetes, infectious
diseases. Analytical models to derive estimates for historically
variant population risk factors and physiological rate parameters.
Analysis of familial data to separately estimate inherited and environmental
risks. Basic population genetics of dominant, recessive, and non-deleterious
inherited risk factors.
BE.103
Introduction to Physiological Modeling
Introduction to organ anatomy and physiology in terms of structure
and function from a quantitative engineering perspective. Subject
provides a quantitative understanding of how chemical and environmental
agents are able to affect tissue or organ function. Specifically,
these effects are analyzed in terms of tissue-level mechanism including
molecular transport, metabolism, and effects on cell function. Subject
provides a problem-oriented perspective on organ function, which
integrates toxicology, pharmacology, and bioengineering.
BE.104J
(1.081J, ESD.053J)
Chemicals in the Environment: Toxicology and Public Health
The challenges of defining a relationship between exposure to environmental
chemicals and human disease are illustrated in case studies of local
and national interest. Material covers epidemiological approaches
to understanding disease causation; evaluation of human exposure
to chemicals, and their internal distribution, metabolism, reactions
with cellular components, and biological effects; and review of
methods underlying regulatory standards, including use of animals.
BE.105J
(5.22J, 10.02J)
Biotechnology and Engineering
Illustrates how the principles of chemistry, biology, and engineering
are integrated to create new products for human health and consumption.
Uses case-study format to examine recently developed products of
pharmaceutical and biotechnology industries: how a product evolves
from initial idea, through patents, testing, evaluation, production,
and marketing. Emphasizes scientific and engineering principles,
as well as the responsibility scientists, engineers, and business
executives have for the consequences of their technology. Enrollment
limited.
BE.106
Infectious Agents and the Environment
Introductory microbiology from a systems perspective, with consideration
of microbial diversity, population dynamics, and genomics. Emphasis
on the delicate balance between microbes and humans, and changes
that result in the emergence of infectious diseases and antimicrobial
resistance. Case study approach covers topics such as vaccines,
toxins, biodefense, and infections including Legionnaire’s
disease, tuberculosis, Helicobacter pylori, and plague.
LABORATORY CORE SUBJECT
Choose one from among:
BE.109
Laboratory Fundamentals
in Biological Engineering
Experimental approaches to understanding the biological effects
of environmental chemicals and microorganisms. Analysis of complex
chemical mixtures; cellular toxicity and mutations; genetic factors
in disease susceptibility; and methods for assessing low-level infectious
agents.
7.02
Introduction to Experimental
Biology
As an introduction to techniques in biochemistry, microbiology,
and cell biology, this subject prepares students to design, carry
out, and interpret results of laboratory experiments.
5.310
Laboratory Chemistry
This subject provides an introduction to experimental chemistry,
including preparation and analysis of materials, chromatography,
spectroscopy, data analysis, and elementary synthesis.
RESTRICTED ELECTIVES
Choose one from among:
BE.901
Special Topics in Toxicology and Environmental Health
BE.URG
Special Projects in Undergraduate Research
1.080
Environmental Chemistry & Biology
1.725J
(ESD.151J) Chemicals in the Environment: Fate and Transport
1.89
Environmental Microbiology
5.07Biological
Chemistry
7.05
General Biochemistry
7.06
Cell Biology
7.28
Molecular Biology
12.807 (5.23)
Atmospheric Chemistry
17.32
Environmental Politics and Policy
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