Dr. Steven F. Nagle
Instructor of Biological Engineering
Bioinstrumentation Lab Wiki
E-mail: sfnagle@mit.edu
Office: 16-239
Phone: (617) 324-8150
Courses: 20.309 and 20.345
Teaching and Research:
My teaching and research activities primarily include the development of novel bioinstrumentation for research, as well as for standard and miniaturized medical devices. I focus on teaching a practical understanding of the limits of detection and hardware development principles. Projects have included an educational low-cost atomic force microscope and it's nanoprobes, a low-cost, open-source, quantitative PCR machine, a microfluidic device to demonstrate chemotaxis, in collaboration with Prof. Roman Stocker of Course 1, and a hand-held spectrometer to noninvasively measure human hemoglobin levels.
In 20.309, students build precision bioinstrumentation including:
- An epi-fluorescent microscope, and
- A quantitative DNA melting instrument.
In 20.345, students work on self-motivated projects including:
- Optical tweezers,
- Atomic Force Microscopy,
- quantitative PCR,
- Confocal microscopy,
- Super resolution microscopy,
- Microfluidic chemotaxis,
- Structured light microscopy,
- Mucin rheology, and
- Suspended Microchannel Resonators (SMR) to measure individual cell growth
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