Biological Engineering Accelerator Mass Spectrometry
The Biological Engineering Accelerator Mass Spectrometry [BEAMS] Lab at the
Massachusetts Institute of Technology was established to be a high-throughput
facility for biomedical applications of AMS such as pharmacokinetics, metabolite
profiling, toxicology, and microdosing.
Our current AMS instrument incorporates an exceptionally compact 1 MV particle
accelerator and was designed to be a two-isotope instrument for analysis
of 14C- or 3H-labeled
compounds. It is equipped with a gas-accepting ion source to facilitate continuous
sampling. Proprietary interfaces for on-line sample gasification are coupled
to the AMS instrument to allow rapid introduction and analysis of samples in
liquid or other form.
The BEAMS Lab engages in collaborative research with academic
and industrial partners. It is also a center for research into
improving the accessibility of AMS to chemical analysts with a new, more compact
spectrometer under construction and continuing development of sample interfaces.
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