Overview of the Program


The program for ISBP2000 has been finalized. Below, please find a conference overview, program overview and a detailed schedule .

 
  Morning Afternoon Evening

Monday

Sept 11

Opening Remarks

Session I:
Applications: Commodity, Specialty Polymer & Chemicals

 

Session II:
Applications: Medical

 
Symposium Reception at the MIT Faculty Club

Tuesday

Sept 12

Session III:
Physical, Chemical and Structural Characterization of PHAs
 

Session IV:
Biodegredation of Polyesters

 
 

Wednesday

Sept 13

Session V:
Microbial Physiology and Ecology of Polyester Formation

Session VI

Catalysis
 

Thursday

Sept 14

Session VII:
Metabolic Engineering in Bacteria

Session VIII:
PHA Production in Plants

 
Banquet at the Museum of Science

Friday

Sept 15
Session IX:
Novel Applications and Technology

Conference Hall open for informal meetings and discussion.


ISBP2000 Program

 

 

 

The 8th International Symposium on Biological Polyesters Preliminary Program

September 11-15, 2000 Cambridge, Massachusetts

Opening Address

Title and Speaker TBD

Session I: Applications: Commodity, Specialty Polymer & Chemicals

Chairs: C. Christenson, DOW Corporation and P. Gruber, Cargill DOW

* = confirmed participant

Tentative Titles

*

Chris Christenson

DOW Corporation

A Molecular Architectural View on the Polyhydroxyalkanoates

*

Pat Gruber

Cargill DOW

NatureWorks PLA

*

Robert Whitehouse

Metabolix

Polyhydroxyalkanoates as Novel Binders for Ceramic and Metal Powders

 

Ga-er Yu

Clarkson University

PHA-Ethylene Oxide Diblock Polymers

*

Young Baek Kim

CSK

Modification and Applications of PHAs

Session II: Applications: Medical

Chair: D. Martin, Tepha

*

David P. Martin

Tepha

PHAs: Versatile Absorbable Polyesters for Medical Applications

*

John Mayer

Children's Hospital, Boston

Tissue Engineering of Heart Valves

 

TBA

TBA

Session III: Physical, Chemical and Structural Characterization of PHAs

Chair: D. Seebach, ETH Zürich

*

Dieter Seebach

ETH Zürich

Secondary Structures of Oligo-(Hydroxyalkanoates) and of their NH-Analogs, the Beta-Peptides

*

Michael M. Satkowski

The Procter & Gamble Company

Physical Properties and Deformation Behavior of Poly(hydroxyalkanoate) Copolymers

*

Aaron Kelley

University of Minnesota

Characterization of PHA Microstructures in Polymer Films and in Native Granules

*

Kumar Sudesh

RIKEN Institute

Insight into the Microstructures of in vivo PHA Inclusions

*

Robert H. Marchessault

McGill University

Computer Simulation of in vitro Formation of PHB Granules: Particulate Polymerization

Session IV: Biodegradation of Polyesters

Chair: D. Jendrossek, Universität Stuttgart Institut für Mikrobiologie

*

Dieter Jendrossek

Universität Stuttgart

Novel PHB Depolymerase Activities

*

Zhihua Gan

RIKEN Institute

Atomic Force Microscopy Visualization of Lamellar Crystal Morphology for Melt-Crystallized Poly(ethylene succinate) Ultrathin Film Before and After Enzymatic Degradation

*

Sung Chul Yoon

Gyeongsang National University

Kinetic Analysis of PHA-Inclusion Degradation in Bacteria

*

Yoshihiro Kikkawa

Tokyo Institute of Technology

Crystal Growth and Enzymatic Degradation of Thin Films for Poly[(R)-3-hydroxybutyrate-co-10mol%-6-hydroxyhexanoate]

Session V: Microbial Physiology and Ecology of Polyester Formation

Chair: S. Goodwin, University of Massachusetts Amherst

*

Jun Sun

K.U. Leuven

Regulation of Poly-3-hydroxybutyrate (PHB) Biosynthesis by Ammonium in Azospirillium brasilense Sp7

*

Akira Maehara

RIKEN Institute

Paracoccus denitrification PhaR Binds to a Short DNA Region Located Upstream of the Phasin Gene and Regulates its Expression in vitro

*

Luiziana Ferreira da Silva

Instituto de Pesquisas Tecnológicas do Estado de Sãu Paulo

P3HB and P3HB-co-3HV Production by Burkholderia and Other Bacterial Strains Isolated in Brazil

*

Bernd H.A. Rehm

Universität Münster

Polyhydroxybutyrate Production by a Newly Isolated, Extremely Halophilic Archaebacterium and Analysis of the Respective Granule-Bound Polyhydroxybutyrate Synthase

 

GQ Chen

Tsinghua University

Bacterial Synthesis of Polyhydroxyalkanoates is Substrate Dependent

 

José Geraldo da Cruz Pradella

Instituto de Pesquisas Tecnológicas do Estado de Sãu Paulo

TBA

Session VI: Catalysis

Chairs: G. York, Massachusetts Institute of Technology and B. Witholt, ETH Zürich

*

Bernard Witholt

ETH Zürich

What More Do We Want to Know About PHA Synthesis and How Will That Help Us?

*

JoAnne Stubbe

Massachusetts Institute of Technology

Mechanistic Paradigm for Class I and Class III PHA Synthases

*

Shiming Zhang

University of Massachusetts, Amherst

Characterization of the Polyhydroxybutyrate Synthase from Ralstonia eutropha

*

Tomoki Erata

Hokkaido University

In vitro PHA Synthesis with Co-A Recycling and ATP Regeneration

*

Gregory York

Massachusetts Institute of Technology

Analysis of Polyhydroxyalkanoate Synthesis in vivo in Ralstonia eutropha phaC PHA Synthase and phaP Phasin Gene Replacement Strains

Session VII: Metabolic Engineering in Bacteria

Chairs: F. Skraly, Metabolix and A. Steinbüchel, Universität Münster

*

Alexander Steinbüchel

Universität Münster

In vivo and in vitro Engineering of PHA Biosynthesis Pathways

*

Yoshiharu Doi

RIKEN Institute

Metabolic Engineering for the Microbial Production of Novel Copolyesters of 3-hydroxybutyrate and 3-hydroxyalkanoates (C6-C12)

*

Sang Yup Lee

KAIST

Production of SCL-MCL Copolymer PHAs by Wild Type and Recombinant Bacteria

*

Ilana Aldor

University of California, Berkeley

Metabolic Engineering of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Production in Recombinant Salmonella typhimurium

*

Phillip Green

The Procter & Gamble Company

Production of C3/C4/C6/C8 PHA Copolymer in Native Ralstonia eutropha

Session VIII: PHA Production in Plants

Chairs: K. Snell, Metabolix and V. Mittendorf, BASF

*

Yves Poirier

Université de Lausanne

Synthesis of PHAs in Plants: Past, Present, and Future

*

Karen Bohmert

Max Planck Institute

PHB Production in Arabidopsis, Tobacco, and Potato

*

Andreas Lössl

Universität München

Production of Polyhydroxybutyric Acid (PHB) Using Chloroplast Transformation

*

Volker Mittendorf

BASF

Diversion of Plastidial Fatty Acid Biosynthesis Intermediates for MCLPHA Biosynthesis in Arabidopsis

*

Uta Breuer

UFZ Centre for Environmental Research

Biopolymer Production with Transgenic Yeast?

Session IX: Novel Applications & Technology

Chair: R. Marchessault, McGill University

*

Tina Lütke-Eversloh

Universität Münster

Biosynthesis of Poly(3-hydroxybutyrate-co-3-mercaptopropionate) as a Representitive of a Novel Class of biopolymers: Polythioesters

*

Magnus Rueping

ETH Zürich

Synthesis of Fluorine- and Fluorescence Labeled Oligo[(R)-3-hydroxybutanoic acids] (OHB) for Structural Investigations

*

Valérie Langlois

Université Paris

Preparation of Bacterial Polyesters with Carboxylic Acid End Groups in Side Chains

*

Friedrich Srienc

University of Minnesota

Design and Biosynthesis of Nanostructured Polyhydroxyalkanoates

*

Gjalt Huisman

Maxygen

Exploring Metabolic Space by Directed Evolution

*

Peter Bluford

Sangamo BioSciences, Inc.

Engineered Transcription Factors for Metabolic Engineering

*

Anthony J. Sinskey

Massachusetts Institute of Technology

Challenges and Opportunities with PHAs

 

Poster Session I

Chair: F. Skraly, Metabolix

 

ISBP2000 Schedule

ISBP2000

ISBP2000 Schedule

Monday 9.11.2000

8:00-9:00a: Conference Registration (tentative location: Tang Vestibule) (1h30m)

9:00-9:30a: Opening Remarks AJ Sinskey (location: Conference Hall) (30m)

9:30-12:45p: Session I: Applications: Commodity, Specialty Polymer & Chemicals (3h15m)

9:30-10:15a C Christenson (45m) A Molecular Architectural View on the Polyhydroxyalkanoates

10:15-11:00a P Gruber (45m) NatureWorksÔ PLA

11:00-11:15a Coffee Break (15m)

11:15-12:00p R Whitehouse (45m) Polyhydroxyalkanoates as Novel Binders for Ceramic and Metal Powders

12:00-12:45p G Yu (45m) PHA-Ethylene Oxide Diblock Polymers (tentative)

12:45-1:45p: Lunch & Informal Poster Session (1h)

1:45-5:00p: Session I (cont'd), Session II: Applications: Medical (3h15m)

1:45-2:30p YB Kim (45m) Modification and Applications of PHAs

2:30-3:15p D Martin (45m) PHAs: Versatile Absorbable Polyesters for Medical Applications

3:15-3:30p Coffee Break (15m)

3:30-4:15p J Mayer (45m) Tissue Engineering of Heart Valves

4:15-5:00p TBA (45m)

6:00-9:00p: Welcome Reception at the MIT Faculty Club

Tuesday 9.12.2000

8:30-12:30p: Session III: Physical, Chemical and Structural Characterization of PHAs (4h)

8:30-9:15a D Seebach (45m) Secondary Structures of Oligo-(Hydroxyalkanoates) and of their NH-Analogs, the Beta-Peptides

9:15-10:00a MM Satkowski (45m) Physical Properties and Deformation Behavior of Poly(hydroxyalkanoate) Copolymers

10:00-10:15a Coffee Break (15m)

10:15-11:00a A Kelly (45m) Characterization of PHA Microstructures in Polymer Films and in Native Granules

11:00-11:45 K Sudesh (45m) Insight into the Microstructures of in vivo PHA Inclusions

11:45-12:30p RH Marchessault (45m) Computer Simulation of in vitro Formation of PHB Granules: Particulate Polymerization

12:30-1:30p: Lunch & Informal Poster Session (1h)

1:30-4:45p: Session IV: Biodegradation of Polyesters (3h15m)

1:30-2:15p D Jendrossek (45m) Novel PHB Depolymerase Activities

2:15-3:00p Z Gan (45m) Atomic Force Microscopy Visualization of Lamellar Crystal Morphology for Melt-Crystallized Poly(ethylene succinate) Ultrathin Film Before and After Enzymatic Degradation

3:00-3:15p Coffee Break (15m)

3:15-4:00p SC Yoon (45m) Kinetic Analysis of PHA-Inclusion Degradation in Bacteria

4:00-4:45p Y Kikkawa (45m) Crystal Growth and Enzymatic Degradation of Thin Films for Poly[(R)-3-hydroxybutyrate-co-10mol%-6-hydroxyhexanoate]

4:45-6:00p: Poster Session (1h15m)

Evening: Free Time

Wednesday 9.13.2000

8:30-12:45p Session V: Microbial Physiology and Ecology of Polyester Formation (4h)

8:30-9:10a J Sun (40m) Regulation of Poly-3-hydroxybutyrate (PHB) Biosynthesis by Ammonium in Azospirillium brasilense Sp7

9:10-9:50a A Maehara (40m) Paracoccus denitrification PhaR Binds to a Short DNA Region Located Upstream of the Phasin Gene and Regulates its Expression in vitro

9:50-10:30a LF daSilva (40m) P3HB and P3HB-co-3HV Production by Burkholderia and Other Bacterial Strains Isolated in Brazil

10:30-10:45a Coffee Break (15m)

10:45-11:25a BHA Rhem (40m) Polyhydroxybutyrate Production by a Newly Isolated, Extremely Halophilic Archaebacterium and Analysis of the Respective Granule-Bound Polyhydroxybutyrate Synthase

11:25-12:05p GQ Chen (40m) Bacterial Synthesis of Polyhydroxyalkanoates is Substrate Dependent

12:05-12:45p JGC Pradella (40m) TBA

12:45-1:45p: Lunch & Informal Poster Session (1h)

1:45-5:45p: Session VI: Catalysis (4h)

1:45-2:30p B Witholt (45m) What More Do We Want to Know About PHA Synthesis and How Will That Help Us?

2:30-3:15p J Stubbe (45m) Mechanistic Paradigm for Class I and Class II PHA Synthases

3:15-4:00p S Zhang (45m) Characterization of the Polyhydroxybutyrate Synthase from Ralstonia eutropha

4:00-4:15p Coffee Break (15m)

4:15-5:00p T Erata (45m) In vitro PHA Synthesis with Co-A Recycling and ATP Regeneration

5:00-5:45p G York (45m) Analysis of PHA Synthesis in vivo

Evening: Free Time

Thursday 9.14.2000

8:30-12:35p: Session VII: Metabolic Engineering in Bacteria (4h05m)

8:30-9:25a A Steinbüchel (55m) In vivo and in vitro Engineering of PHA Biosynthesis Pathways

9:25-10:20a Y Doi (55m) Metabolic Engineering for the Microbial Production of Novel Copolyesters of 3-hydroxybutyrate and 3-hydroxyalkanoates (C6-C12)

10:20-10:35a Coffee Break (15m)

10:35-11:15a SY Lee (40m) Production of SCL-MCL Copolymer PHAs by Wild Type and Recombinant Bacteria

11:15-11:55a I Aldor (40m) Metabolic Engineering of Poly(3-hydroxybutyrate-co-3-hyrdoxyvalerate) Production in Recombinant Salmonella typhimurium

11:55-12:35a P Green (40m) Production of C3/C4/C6/C8 PHA Copolymer in Native Ralstonia eutropha

12:35-2:30p: Free Time to Have Lunch at Local Restaurants (1h55m)

2:30-5:30p: Session VIII: PHA Production in Plants (3h)

2:30-3:15p Y Poirier (45m) Synthesis of PHAs in Plants: Past, Present, and Future

3:15-3:45p K Bohmert (30m) PHB Production in Arabidopsis, Tobacco, and Potato

3:45-4:15p A Lössl (30m) Production of Polyhydroxybutyric Acid (PHB) Using Chloroplast Transformation

4:15-4:30p Coffee Break (15m)

4:30-5:00p V Mittendorf (30m) Diversion of Plastidial Fatty Acid Biosynthesis Intermediates for MCLPHA Biosynthesis in Arabidopsis

5:00-5:30p U Breuer (30m) Biopolymer Production with Transgenic Yeast?

6:30-10:30p: Banquet and Omni Theatre Viewing at the Museum of Science

Transportation provided from the Tang Center

Friday 9.15.2000

8:30-12:40p: Session IX: Novel Applications and Technology (4h10m)

8:30-9:05a T Lütke-Eversloh (35m) Biosynthesis of Poly(3-hydroxybutyrate-co-3-mercaptopropionate) as a Representitive of a Novel Class of biopolymers: Polythioesters

9:05-9:40a M Reuping (35m) Synthesis of Fluorine- and Fluorescence Labeled Oligo[(R)-3-hydroxybutanoic acids] (OHB) for Structural Investigations

9:40-10:15a V Langlois (35m) Preparation of Bacterial Polyesters with Carboxylic Acid End Groups in Side Chains

10:15-10:30a Coffee Break (15m)

10:30-11:05a F Srienc (35m) Design and Biosynthesis of Nanostructured Polyhydroxyalkanoates

11:05-11:40a G Huisman (35m) Exploring Metabolic Space by Directed Evolution

11:40-12:15a P Bluford (35m) Engineered Transcription Factors for Metabolic Engineering

12:15-12:40p AJ Sinskey (25m) Challenges and Opportunities with PHAs

12:40p: Meeting Adjourned

12:40-5:00p: Conference Halls Open for Informal Meetings and Discussion (4h20m)




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