Overview of the Program |
|
| Morning | Afternoon | Evening | |
Monday Sept 11 |
Opening Remarks |
Session II: |
Symposium Reception at the MIT Faculty Club |
Tuesday Sept 12 |
Session III: |
Session IV: |
|
Wednesday Sept 13 |
Session V: |
Session VI |
|
Thursday Sept 14 |
Session VII: |
Session VIII: |
Banquet at the Museum of
Science |
Friday Sept 15 |
Session IX: Novel Applications and Technology
| Conference Hall open for informal meetings and discussion. |
|
|
ISBP2000 Program |
|
The 8th International Symposium on Biological Polyesters Preliminary Program September 11-15, 2000 Cambridge, Massachusetts |
||
|
Opening Address Title and Speaker TBD |
||
|
Session I: Applications: Commodity, Specialty Polymer & Chemicals Chairs: C. Christenson, DOW Corporation and P. Gruber, Cargill DOW |
||
|
* = confirmed participant |
Tentative Titles |
|
|
* |
Chris Christenson DOW Corporation |
A Molecular Architectural View on the Polyhydroxyalkanoates |
|
* |
Pat Gruber Cargill DOW |
NatureWorks PLA |
|
* |
Robert Whitehouse Metabolix |
Polyhydroxyalkanoates as Novel Binders for Ceramic and Metal Powders |
|
Ga-er Yu Clarkson University |
PHA-Ethylene Oxide Diblock Polymers |
|
|
* |
Young Baek Kim CSK |
Modification and Applications of PHAs |
|
Session II: Applications: Medical Chair: D. Martin, Tepha |
||
|
* |
David P. Martin Tepha |
PHAs: Versatile Absorbable Polyesters for Medical Applications |
|
* |
John Mayer Children's Hospital, Boston |
Tissue Engineering of Heart Valves |
|
TBA |
TBA |
|
|
Session III: Physical, Chemical and Structural Characterization of PHAs Chair: D. Seebach, ETH Zürich |
||
|
* |
Dieter Seebach ETH Zürich |
Secondary Structures of Oligo-(Hydroxyalkanoates) and of their NH-Analogs, the Beta-Peptides |
|
* |
Michael M. Satkowski The Procter & Gamble Company |
Physical Properties and Deformation Behavior of Poly(hydroxyalkanoate) Copolymers |
|
* |
Aaron Kelley University of Minnesota |
Characterization of PHA Microstructures in Polymer Films and in Native Granules |
|
* |
Kumar Sudesh RIKEN Institute |
Insight into the Microstructures of in vivo PHA Inclusions |
|
* |
Robert H. Marchessault McGill University |
Computer Simulation of in vitro Formation of PHB Granules: Particulate Polymerization |
|
Session IV: Biodegradation of Polyesters Chair: D. Jendrossek, Universität Stuttgart Institut für Mikrobiologie |
||
|
* |
Dieter Jendrossek Universität Stuttgart |
Novel PHB Depolymerase Activities |
|
* |
Zhihua Gan RIKEN Institute |
Atomic Force Microscopy Visualization of Lamellar Crystal Morphology for Melt-Crystallized Poly(ethylene succinate) Ultrathin Film Before and After Enzymatic Degradation |
|
* |
Sung Chul Yoon Gyeongsang National University |
Kinetic Analysis of PHA-Inclusion Degradation in Bacteria |
|
* |
Yoshihiro Kikkawa Tokyo Institute of Technology |
Crystal Growth and Enzymatic Degradation of Thin Films for Poly[(R)-3-hydroxybutyrate-co-10mol%-6-hydroxyhexanoate] |
|
Session V: Microbial Physiology and Ecology of Polyester Formation Chair: S. Goodwin, University of Massachusetts Amherst |
||
|
* |
Jun Sun K.U. Leuven |
Regulation of Poly-3-hydroxybutyrate (PHB) Biosynthesis by Ammonium in Azospirillium brasilense Sp7 |
|
* |
Akira Maehara RIKEN Institute |
Paracoccus denitrification PhaR Binds to a Short DNA Region Located Upstream of the Phasin Gene and Regulates its Expression in vitro |
|
* |
Luiziana Ferreira da Silva Instituto de Pesquisas Tecnológicas do Estado de Sãu Paulo |
P3HB and P3HB-co-3HV Production by Burkholderia and Other Bacterial Strains Isolated in Brazil |
|
* |
Bernd H.A. Rehm Universität Münster |
Polyhydroxybutyrate Production by a Newly Isolated, Extremely Halophilic Archaebacterium and Analysis of the Respective Granule-Bound Polyhydroxybutyrate Synthase |
|
GQ Chen Tsinghua University |
Bacterial Synthesis of Polyhydroxyalkanoates is Substrate Dependent |
|
|
José Geraldo da Cruz Pradella Instituto de Pesquisas Tecnológicas do Estado de Sãu Paulo |
TBA |
|
|
Session VI: Catalysis Chairs: G. York, Massachusetts Institute of Technology and B. Witholt, ETH Zürich |
||
|
* |
Bernard Witholt ETH Zürich |
What More Do We Want to Know About PHA Synthesis and How Will That Help Us? |
|
* |
JoAnne Stubbe Massachusetts Institute of Technology |
Mechanistic Paradigm for Class I and Class III PHA Synthases |
|
* |
Shiming Zhang University of Massachusetts, Amherst |
Characterization of the Polyhydroxybutyrate Synthase from Ralstonia eutropha |
|
* |
Tomoki Erata Hokkaido University |
In vitro PHA Synthesis with Co-A Recycling and ATP Regeneration |
|
* |
Gregory York Massachusetts Institute of Technology |
Analysis of Polyhydroxyalkanoate Synthesis in vivo in Ralstonia eutropha phaC PHA Synthase and phaP Phasin Gene Replacement Strains |
|
Session VII: Metabolic Engineering in Bacteria Chairs: F. Skraly, Metabolix and A. Steinbüchel, Universität Münster |
||
|
* |
Alexander Steinbüchel Universität Münster |
In vivo and in vitro Engineering of PHA Biosynthesis Pathways |
|
* |
Yoshiharu Doi RIKEN Institute |
Metabolic Engineering for the Microbial Production of Novel Copolyesters of 3-hydroxybutyrate and 3-hydroxyalkanoates (C6-C12) |
|
* |
Sang Yup Lee KAIST |
Production of SCL-MCL Copolymer PHAs by Wild Type and Recombinant Bacteria |
|
* |
Ilana Aldor University of California, Berkeley |
Metabolic Engineering of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Production in Recombinant Salmonella typhimurium |
|
* |
Phillip Green The Procter & Gamble Company |
Production of C3/C4/C6/C8 PHA Copolymer in Native Ralstonia eutropha |
|
Session VIII: PHA Production in Plants Chairs: K. Snell, Metabolix and V. Mittendorf, BASF |
||
|
* |
Yves Poirier Université de Lausanne |
Synthesis of PHAs in Plants: Past, Present, and Future |
|
* |
Karen Bohmert Max Planck Institute |
PHB Production in Arabidopsis, Tobacco, and Potato |
|
* |
Andreas Lössl Universität München |
Production of Polyhydroxybutyric Acid (PHB) Using Chloroplast Transformation |
|
* |
Volker Mittendorf BASF |
Diversion of Plastidial Fatty Acid Biosynthesis Intermediates for MCLPHA Biosynthesis in Arabidopsis |
|
* |
Uta Breuer UFZ Centre for Environmental Research |
Biopolymer Production with Transgenic Yeast? |
|
Session IX: Novel Applications & Technology Chair: R. Marchessault, McGill University |
||
|
* |
Tina Lütke-Eversloh Universität Münster |
Biosynthesis of Poly(3-hydroxybutyrate-co-3-mercaptopropionate) as a Representitive of a Novel Class of biopolymers: Polythioesters |
|
* |
Magnus Rueping ETH Zürich |
Synthesis of Fluorine- and Fluorescence Labeled Oligo[(R)-3-hydroxybutanoic acids] (OHB) for Structural Investigations |
|
* |
Valérie LangloisUniversité Paris |
Preparation of Bacterial Polyesters with Carboxylic Acid End Groups in Side Chains |
|
* |
Friedrich Srienc University of Minnesota |
Design and Biosynthesis of Nanostructured Polyhydroxyalkanoates |
|
* |
Gjalt Huisman Maxygen |
Exploring Metabolic Space by Directed Evolution |
|
* |
Peter Bluford Sangamo BioSciences, Inc. |
Engineered Transcription Factors for Metabolic Engineering |
|
* |
Anthony J. Sinskey Massachusetts Institute of Technology |
Challenges and Opportunities with PHAs |
|
Poster Session I Chair: F. Skraly, Metabolix |
||
|
ISBP2000 Schedule |
|
ISBP2000 Schedule
Monday 9.11.2000
8:00-9:00a: Conference Registration (tentative location: Tang Vestibule) (1h30m)
9:00-9:30a: Opening Remarks AJ Sinskey (location: Conference Hall) (30m)
9:30-12:45p: Session I: Applications: Commodity, Specialty Polymer & Chemicals (3h15m)
9:30-10:15a C Christenson (45m) A Molecular Architectural View on the Polyhydroxyalkanoates
10:15-11:00a
11:00-11:15a Coffee Break (15m)
11:15-12:00p R Whitehouse (45m) Polyhydroxyalkanoates as Novel Binders for Ceramic and Metal Powders
12:00-12:45p G Yu (45m) PHA-Ethylene Oxide Diblock Polymers (tentative)
12:45-1:45p: Lunch & Informal Poster Session (1h)
1:45-5:00p: Session I (cont'd), Session II: Applications: Medical (3h15m)
1:45-2:30p YB Kim (45m) Modification and Applications of PHAs
2:30-3:15p D Martin (45m) PHAs: Versatile Absorbable Polyesters for Medical Applications
3:15-3:30p Coffee Break (15m)
3:30-4:15p J Mayer (45m) Tissue Engineering of Heart Valves
4:15-5:00p TBA (45m)
6:00-9:00p: Welcome Reception at the MIT Faculty Club
Tuesday 9.12.2000
8:30-12:30p: Session III: Physical, Chemical and Structural Characterization of PHAs (4h)
8:30-9:15a D Seebach (45m) Secondary Structures of Oligo-(Hydroxyalkanoates) and of their NH-Analogs, the Beta-Peptides
9:15-10:00a MM Satkowski (45m) Physical Properties and Deformation Behavior of Poly(hydroxyalkanoate) Copolymers
10:00-10:15a Coffee Break (15m)
10:15-11:00a A Kelly (45m) Characterization of PHA Microstructures in Polymer Films and in Native Granules
11:00-11:45 K Sudesh (45m) Insight into the Microstructures of in vivo PHA Inclusions
11:45-12:30p RH Marchessault (45m) Computer Simulation of in vitro Formation of PHB Granules: Particulate Polymerization
12:30-1:30p: Lunch & Informal Poster Session (1h)
1:30-4:45p: Session IV: Biodegradation of Polyesters (3h15m)
1:30-2:15p D Jendrossek (45m) Novel PHB Depolymerase Activities
2:15-3:00p Z Gan (45m) Atomic Force Microscopy Visualization of Lamellar Crystal Morphology for Melt-Crystallized Poly(ethylene succinate) Ultrathin Film Before and After Enzymatic Degradation
3:00-3:15p Coffee Break (15m)
3:15-4:00p SC Yoon (45m) Kinetic Analysis of PHA-Inclusion Degradation in Bacteria
4:00-4:45p Y Kikkawa (45m) Crystal Growth and Enzymatic Degradation of Thin Films for Poly[(R)-3-hydroxybutyrate-co-10mol%-6-hydroxyhexanoate]
4:45-6:00p: Poster Session (1h15m)
Evening: Free Time
Wednesday 9.13.2000
8:30-12:45p Session V: Microbial Physiology and Ecology of Polyester Formation (4h)
8:30-9:10a J Sun (40m) Regulation of Poly-3-hydroxybutyrate (PHB) Biosynthesis by Ammonium in Azospirillium brasilense Sp7
9:10-9:50a A Maehara (40m) Paracoccus denitrification PhaR Binds to a Short DNA Region Located Upstream of the Phasin Gene and Regulates its Expression in vitro
9:50-10:30a LF daSilva (40m) P3HB and P3HB-co-3HV Production by Burkholderia and Other Bacterial Strains Isolated in Brazil
10:30-10:45a Coffee Break (15m)
10:45-11:25a BHA Rhem (40m) Polyhydroxybutyrate Production by a Newly Isolated, Extremely Halophilic Archaebacterium and Analysis of the Respective Granule-Bound Polyhydroxybutyrate Synthase
11:25-12:05p GQ Chen (40m) Bacterial Synthesis of Polyhydroxyalkanoates is Substrate Dependent
12:05-12:45p JGC Pradella (40m) TBA
12:45-1:45p: Lunch & Informal Poster Session (1h)
1:45-5:45p: Session VI: Catalysis (4h)
1:45-2:30p B Witholt (45m) What More Do We Want to Know About PHA Synthesis and How Will That Help Us?
2:30-3:15p J Stubbe (45m) Mechanistic Paradigm for Class I and Class II PHA Synthases
3:15-4:00p S Zhang (45m) Characterization of the Polyhydroxybutyrate Synthase from Ralstonia eutropha
4:00-4:15p Coffee Break (15m)
4:15-5:00p T Erata (45m) In vitro PHA Synthesis with Co-A Recycling and ATP Regeneration
5:00-5:45p G York (45m) Analysis of PHA Synthesis in vivo
Evening: Free Time
Thursday 9.14.2000
8:30-12:35p: Session VII: Metabolic Engineering in Bacteria (4h05m)
8:30-9:25a A Steinbüchel (55m) In vivo and in vitro Engineering of PHA Biosynthesis Pathways
9:25-10:20a Y Doi (55m) Metabolic Engineering for the Microbial Production of Novel Copolyesters of 3-hydroxybutyrate and 3-hydroxyalkanoates (C6-C12)
10:20-10:35a Coffee Break (15m)
10:35-11:15a SY Lee (40m) Production of SCL-MCL Copolymer PHAs by Wild Type and Recombinant Bacteria
11:15-11:55a I Aldor (40m) Metabolic Engineering of Poly(3-hydroxybutyrate-co-3-hyrdoxyvalerate) Production in Recombinant Salmonella typhimurium
11:55-12:35a P Green (40m) Production of C3/C4/C6/C8 PHA Copolymer in Native Ralstonia eutropha
12:35-2:30p: Free Time to Have Lunch at Local Restaurants (1h55m)
2:30-5:30p: Session VIII: PHA Production in Plants (3h)
2:30-3:15p Y Poirier (45m) Synthesis of PHAs in Plants: Past, Present, and Future
3:15-3:45p K Bohmert (30m) PHB Production in Arabidopsis, Tobacco, and Potato
3:45-4:15p A Lössl (30m) Production of Polyhydroxybutyric Acid (PHB) Using Chloroplast Transformation
4:15-4:30p Coffee Break (15m)
4:30-5:00p V Mittendorf (30m) Diversion of Plastidial Fatty Acid Biosynthesis Intermediates for MCLPHA Biosynthesis in Arabidopsis
5:00-5:30p U Breuer (30m) Biopolymer Production with Transgenic Yeast?
6:30-10:30p: Banquet and Omni Theatre Viewing at the Museum of Science
Transportation provided from the Tang Center
Friday 9.15.2000
8:30-12:40p: Session IX: Novel Applications and Technology (4h10m)
8:30-9:05a T Lütke-Eversloh (35m) Biosynthesis of Poly(3-hydroxybutyrate-co-3-mercaptopropionate) as a Representitive of a Novel Class of biopolymers: Polythioesters
9:05-9:40a M Reuping (35m) Synthesis of Fluorine- and Fluorescence Labeled Oligo[(R)-3-hydroxybutanoic acids] (OHB) for Structural Investigations
9:40-10:15a V Langlois (35m) Preparation of Bacterial Polyesters with Carboxylic Acid End Groups in Side Chains
10:15-10:30a Coffee Break (15m)
10:30-11:05a F Srienc (35m) Design and Biosynthesis of Nanostructured Polyhydroxyalkanoates
11:05-11:40a G Huisman (35m) Exploring Metabolic Space by Directed Evolution
11:40-12:15a P Bluford (35m) Engineered Transcription Factors for Metabolic Engineering
12:15-12:40p AJ Sinskey (25m) Challenges and Opportunities with PHAs
12:40p: Meeting Adjourned
12:40-5:00p: Conference Halls Open for Informal Meetings and Discussion (4h20m)