The challenges at the exciting frontier of Human Genetics are many. We are well on the way to knowing the entire genomic sequence of humans and mouse. This information will facilitate research on several fronts. Our department is involved in the identification of genes involved in the etiology of numerous human diseases and cancers, and fundamental issues of developmental biology, such as aging and sex-determination.

Studies on the function of key genes, both at a molecular level and in an organismal context, are high priority. Among the approaches used in these studies are genetic and biochemical characterization of relevant gene products, and the use of model systems, such as mice and lower eukaryotes. Further, the field of genomics will allow us to address broad questions in genome organization, molecular evolution, and how genes interact to yield complex traits.

Faculty with research programs in human genetics: