J. R. Chabot, J. M. Pedraza, P. Luitel, and A. van Oudenaarden
Stochastic gene expression out-of-steady-state in the cyanobacterial circadian clock
Nature 450, 1249 (2007).

Movie 1: Time-lapse microscopy (left panel: phase contrast; right panel: YFP fluorescence) demonstrating circadian oscillations in single cyanobacterial cells.
AVI

 

B. B. Kaufmann, Q. Yang, J. T. Mettetal, and A. van Oudenaarden
Heritable stochastic switching revealed by single-cell genealogy
PLoS Biology 5, e239 (2007).

Movie 1: This movie show a single OFF cell as it grows over 690 minutes into a small colony of 16 cells. Images show phase contrast image overlaid with fluorescence in purple. Colored circles and zoomed panels (below) highlight the dynamics of four individual cells: the original progenitor cell (1), its first two children (1-1 and 1-2), and its first granddaughter (1-1-1). Before 600 minutes, no cells have fluoresced. In the last 90 minutes, a group of cells all switch nearly synchronously from the OFF to the ON state. Time between images is 30 minutes.
AVI


E. M. Ozbudak, A. Becskei, and A. van Oudenaarden,
A system of counteracting feedback loops regulates Cdc42p actvity during spontaneous cell polarization,
Developmental Cell 9, 565 (2005).

Movie 1: Time-lapse fluorescence microscopy on strain ERT224.1 (wild-type; Gic2(1-208)-GFP). Time is reported in minutes.
AVI

Movie 2: Time-lapse fluorescence microscopy on strain ERT225.1 (rsr1D; Gic2(1-208)-GFP). Time is reported in minutes.
AVI

Movie 3: Time-lapse fluorescence microscopy on strain ERT225.1 (rsr1D; Gic2(1-208)-GFP) demonstrating a budding event. Time is reported in minutes.
AVI

Movie 4: Movie demonstrating the numerical simulations simulating a rsr1D cell treated with latranculin A (b = 0). False color scale denotes the concentration of activated Cdc42p.
AVI

Movie 5: Movie demonstrating the numerical simulations simulating a rsr1DgapD cell (b = 1). False color scale denotes the concentration of activated Cdc42p.
AVI

Movie 6: Movie demonstrating the numerical simulations simulating a rsr1D cell (b = -1). False color scale denotes the concentration of activated Cdc42p.
AVI

A. Upadhyaya, J. R. Chabot, A. Andreeva, A. Samadani, and A. van Oudenaarden,
Probing polymerization forces by using actin-propelled lipid vesicles,
PNAS 100, 4521 (2003).

Movie 1: ActA coated vesicles propelled by actin polymerization (speeded up 60x)
AVI
Quicktime

Movie 2: Large ActA coated vesicle propelled by actin polymerization (speeded up 60x)
AVI Quicktime

Movie 3: Stepping vesicle imaged by phase contrast (left) and fluorescence microscopy (right).
This movie is analysed in Fig. 3 (speeded up 60x).
AVI Quicktime

N. Mittal, E. O. Budrene, M. P. Brenner, and A. van Oudenaarden,
Motility of Escherichia coli cells in clusters formed by chemotactic aggregation,
PNAS 100, 13259 (2003).

Movie 1: Motility of single Escherichia coli cells (red) in a cluster (real time). Snapshots of this movie are displayed in Fig. 1.
AVI

 

A. van Oudenaarden and J. A. Theriot,
Cooperative symmetry breaking by actin filament polymerization in a model for cell motility,
Nature Cell Biology 1, 493 (1999).

Movie 1: Symmetry breaking of ActA coated bead (speeded up 60x)
AVI Quicktime

 

L. A. Cameron, M. J. Footer, A. van Oudenaarden, and J. A. Theriot,
Motility of ActA protein-coated microspheres driven by actin polymerization,
PNAS 96, 4908 (1999).

Movie 1: ActA coated bead propelled by actin polymerization (speeded up 60x)
AVI Quicktime

Movie 2: ActA coated beads propelled by actin polymerization (speeded up 60x)
AVI Quicktime