Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Image courtesy / Benjamin A. Teply
Publications
Brar, G.A., Kiburz, B.M., Zhang, J.E., White, F. and Amon, A. (2006) Rec8 phosphorylation and recombination promote the step-wise loss of cohesions in meiosis. Nature. 441: 532-536.
Clark, A. and Orr-Weaver, T.L. (2006) Sister Chromatid Cohesion at the Centromere: Confrontation between Kinases and Phosphatases? Dev Cell. 5: 544-547.
Farokhzad, O., Cheng, J. Teplly, B. Sherifi, I., Jon, S.Y., Yantoff, P., Richie, J.P. and Langer, R. (2006) Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc. Natl. Acad. Sci. 103: 6315-6320.
Krishnan, R. and Lindquist, S. (2005) Structural insights into a yeast prion illuminate nucleation and strain diversity. Nature. 435: 765-772.
Lee, T.I., Jenner, R.G., Boyer, L.A., Guenther, M.G., Levine, S.S., Kumar, R.M., Chevalier, B., Johnstone, S.E., Cole, M.F., Isono, K. Koseki, H., Fucikamik, T., Abe, K., Murray, H.L., Zucker, J.P., Yuan, B., Bell, G.W., Herbolsheimer, E., Hannett, N.M., Sun, K., Odom, D.T., Otte, A.P., Volkert, T.L., Bartel, D.P., Melton, D.A., Gifford, D.K., Jaenisch, R. and Young, R.A. (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell. 125: 301-313.
Lindblad-Toh, K. et al. (Broad Sequencing Platform members) and Lander, E.S. (2005) Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 438: 803-819.
Lu, J., Getz, G., Miska, E.A., Alvarez-Saaverdra, E., Lamb, J., Peck, D., Sweet-Cordero, A., Ebert, B.L., Mak, R.H., Ferrando, A.A., Downing, J.R., Jacks, T., Horvitz, H.R. and Golub, T.R. (2005) MicroRNA expression profiles classify human cancers. Nature. 435: 834-838.
Moffat, J., Grueneberg, D.A., Yang, X., Kim, S.Y., Kloepfer, A.M., Hinkle, G., Pigani, B.M., Eisenhaure, T.M., Luo, B., Grenier, J.K., Carpenter, A.E., Foo, S.Y., Stewart, S.A., Stockwell, B.R., Hacohen, N., Hahn, W.C., Lander, E.S., Sabatini, D.M. and Root, D.E. (2006) A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell. 124: 1283-1298.
Orimo,A., Gupta, P.B., Sgroi, D.C., Arenzana-Seisdedos, F., Delaunay, T., Naeem, R., Carey, V.J., Richardon, A.L. and Weinberg, R.A. (2005) Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 121: 335-348.
Petersen, C.P., Bordeleau, M.E., Pelletier, J. and Sharp, P.A. (2006) Short RNAs repress translation after initiation in mammalian cells. Mol Cell. 214: 533-542.
Sadler, K.C., Amsterdam, A., Soroka, C., Boyer, J. and Hopkins, N. (2005) A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease. Development. 132: 3561-3572.
Subramanian, A., Tamayo, P., Mootha, V.K., Mukherjee, S., Ebert, B.L., Gillette, M.A., Paulovich, A., Pomeroy, S.L., Golub, T.R., Lander, E.S. and Mesirov, J.P. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. U S A. 102: 15545-15550.
Taverna D., Crowley, D., Connolly, M., Bronson, R.T. and Hynes, R.O. (2005) A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas. Cancer Res. 65: 110324-110329.
Zhang, C.C., Kaba, M., Ge, G., Xie, K., Tong, W., Hug, C. and Lodish, H.F. (2006) Angiopoietin-like proteins stimulate ex vivo expansion of haematopoietic stem cells. Nat Med. 12: 240-245.
