- Xu, L., Shen, S., Hoshida, Y., Subramanian, A., Ross, K., Brunet, J.P., Ramaswamy, S., Mesirov, J.P. and Hynes, R.O. (2008). Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Mol Cancer Res. 6:760-769.
- Wong, S.Y., Crowley, D, Bronson, R.T. and Hynes, R.O. (2008). Analyses of the Role of Endogenous SPARC in mouse models of prostate and breast cancer. Clin. Exp. Metastasis 25: 109-118.
- McCarty, J.H., Barry, M., Crowley, D., Bronson, R.T., Lacy-Hulbert, A. and Hynes, R.O. (2008). Genetic ablation of av integrins in epithelial cells of the eyelid skin and conjunctiva leads to squamous cell carcinoma. Am. J. Path. 172:1740-1747.
- Wong, S.Y. and Hynes, R.O. (2007). Tumor-lymphatic interactions in an activated stromal microenvironment. J. Cell Biochem. 101: 840-850.
- Xu, L. and Hynes, R.O. (2007). GPR56 and TG2: possible roles in suppression of tumor growth by the microenvironment. Cell Cycle. 6:160-165.
- Wong, S.Y., Haack, H., Kissil, J.L., Barry, M., Bronson, R.T., Shen, S.S., Whittaker, C.A., Crowley, D, and Hynes, R.O. (2007). Protein 4.1B suppresses prostate cancer progression and metastasis. Proc. Natl. Acad. Sci. USA 104: 12784-12789.
- Wong, S.Y., Crowley, D, Bronson, R.T. and Hynes, R.O. (2007). Analyses of the Role of Endogenous SPARC in mouse models of prostate and breast cancer. Clinical & Experimental Metastasis (Ms in press).
- Xu, L. and Hynes, R.O. (2006). GPR56 and TG2: possible roles in suppression of tumor growth by the microenvironment. Cell Cycle. 6(2):160-5.
- Xu, L., Begum, S., Hearn, J.D. and Hynes, R. O. (2006). GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. Proc. Natl. Acad. Sci. USA. 103: 9023-9028.
- Wong, S.Y. and Hynes, R.O. (2006). Lymphatic or hematogenous dissemination: how does a metastatic tumor cell decide? Cell Cycle 5: 812-817.
- Taverna, D., Crowley, D., Connolly, M., Bronson, R.T. and Hynes, R.O. (2005). A direct test of potential roles for b3 and b5 integrins in growth and metastasis of murine mammary carcinomas. Cancer Res. 65: 10324-10329.
- Wong, S.Y., Haack, H., Crowley, D., Barry, M., Bronson, R.T. and Hynes. R.O. (2005). Tumor-secreted VEGF-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node metastasis. Cancer Res. 65: 9789-9798.
- Astrof, S., Crowley, D., George, E.L., Fukuda, T., Sekiguchi, K., Hanahan, D. and Hynes, R.O. (2004). Direct test of potential roles of EIIIA and EIIIB alternatively spliced segments of fibronectin in physiological and tumor angiogenesis. Mol. Cell. Biol. 24: 8662-8670.
- Taverna, D., Moher, H., Crowley, D., Borsig.L., Varki, A. and Hynes, R.O. (2004). Increased primary tumor growth in mice null for β3- or β3/β5-integrins or selectins. Proc. Natl. Acad. Sci. USA 101: 763-768.
- Hynes, R.O. (2003). Metastatic potential: generic predisposition of the primary tumor or rare, highly metastatic variants—or both? Cell 113: 1-3.
- Borsig, L., Wong, R., Hynes, R.O., Varki, N.M. and Varki, A. (2002). Synergistic effect of L- and P-selectin in facilitating tumor metastasis in a syngeneic system involving non-mucin ligands - further evidence for selectin inhibition as a mode of heparin action. Proc. Natl. Acad. Sci. USA 99: 2193-2198.
- Reynolds, L., Wyder, L., Lively, J.C., Taverna, D., Robinson, S.D., Huang, X., Sheppard, D, Hart, I., Hynes, R.O. and Hodivala-Dilke, K. (2002). Enhanced pathological angiogenesis in mice lacking β3-integrin or β3- and β5-integrins. Nature Medicine 8: 27-34.
- Taverna, D. and Hynes, R.O. (2001). Reduced blood vessel formation and tumor growth in α5 integrin-negative teratocarcinomas and embryoid bodies. Cancer Res. 61:5255-5261.
- Lawler, J., Miao, W.M., Duquette, M., Bouck, N., Bronson, R.T. and Hynes, R.O. (2001). Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice. Am.J. Path. 159: 1949-1956
- Rodriguez-Manzaneque, J.C., Lane, T.F., Ortega, M.A., Hynes, R.O., Lawler, J. and Iruela-Arispe, M.L. (2001). Thrombospondin-1 suppresses spontaneous tumor growth and angiogenesis and inhibits activation of matrix metalloprotease-9 and mobilisation of VEGF. Proc. Natl. Acad. Sci. USA 98: 12485-12490.
- Clark, E.A., Golub, T.R., Lander, E. and Hynes, R.O. (2000) Genomic analysis of metastasis reveals an essential role for rhoC. Nature, 406: 532-535.
- Taverna, D., Ullman-Culleré, M., Rayburn, H., Bronson, R.T. and Hynes, R.O. (1998). A test of the role of α5 integrin/fibronectin interactions in tumorigenesis. Cancer Res., 58: 848-853.
- Stellmach, V., Volpert, O.V., Crawford, S.E., Lawler, J., Hynes, R.O. and Bouck, N. (1997) Tumor suppressor genes and angiogenesis: the role of p53 in fibroblasts. Eur. J. Cancer 32A: 2394-2400.
- Hynes, R.O., and Plantefaber, L.C. (1991). Integrin receptors for extracellular matrix and their involvement in oncogenic transformation. In Origins of Human Cancer: A Comprehensive Review (Brugge, J., Curran, T., Harlow, E and McCormick, F.). Plainview, NY: Cold Spring Harbor. pp. 293-307.
- Plantefaber, L.C. and Hynes, R.O. (1989). Changes in integrin receptors on oncogenically transformed cells. Cell 56:281-290.
- Wagner, D.D., Ivatt, R., Destree, A.T. and Hynes, R.O. (1981). Similarities and differences between the fibronectins of normal and transformed hamster cells. J. Biol. Chem. 256:11708-11715.
- Senger D.R., Wirth, D.F., Bryant, C. and Hynes, R.O. (1980). Transformation-specific secreted proteins in "Viral Oncogenes", Cold Spring Harbor Symposia 44:651-657.
- Senger, D.R., Wirth, D.F. and Hynes, R.O. (l980). Transformation-specific secreted phosphoproteins. Nature 286:619-621.
- Senger, D.R., Wirth, D.F. and Hynes, R.O. (1979). Transformed mammalian cells secrete specific proteins and phosphoproteins. Cell 16:885-894.
- Mautner, V.M. and Hynes, R.O. (1977). Surface distribution of LETS protein in relation to the cytoskeleton of normal and transformed fibroblasts. J. Cell Biol. 75:743-768.
- Ali, I.U., Mautner, V.M., Lanza, R.P. and Hynes, R.O. (1977). Restoration of normal morphology, adhesion and cytoskeleton in transformed cells by addition of a transformation-sensitive surface protein. Cell 11:115-126.
- Critchley, D.R., Wyke, J.A. and Hynes, R.O. (1976). Cell surface and metabolic labelling of the proteins of normal and transformed chicken cells. Biochim. Biophys. Acta 436:335-352.
- Hynes, R.O. (1976). Cell surface proteins and malignant transformation. Biochim. Biophys. Acta 458:73-107.
- Hynes, R.O. and Wyke, J.A. (1975). Alterations in surface proteins in chicken cells transformed by temperature-sensitive mutants of Rous sarcoma virus. Virology 64:492-504.
- Hynes, R.O. (1974). Role of surface alterations in cell transformation: the importance of proteases and surface proteins. Cell 1:147-158.
- Hynes, R.O. (1973). Alteration of cell-surface proteins by viral transformation and by proteolysis. Proc. Natl. Acad. Sci. USA 70:3170-3174.