History of the Daniel I. C. Wang Lecture on the Frontiers of Biotechnology
The Daniel I. C. Wang Lecture on the Frontiers of Biotechnology Lectureship was established in 1999 through a generous donation from Dr. Noubar Afeyan to acknowledge the enabling technologies and developments that have sustained the growth of biotechnology and life sciences. Some of these include bioprocess engineering (upstream and downstream processes), bioanalytical developments, advanced and new instruments, novel delivery concepts, biomedical devices, rational drug design, computational methods, bioinformatics, and information technology. It is the intent of this Lectureship to recognize and honor achievements on the "frontiers of biotechnology" and the distinguished scientists and engineers responsible for them.
Institute Professor Daniel I. C. Wang
Professor Wang’s present research is in the areas of recombinant protein production using Escherichia coli to increase protein expression by engineering and genetic manipulations. These include the use of magnetically coated fluorocarbons to increase oxygen transfer and two-phase aqueous micellar systems metal chelate affinity purification of proteins. He is also performing studies in animal cell culture with emphasis in the increased production of recombinant proteins and monoclonal antibodies. These include the understanding of cell death using proteomics to profile the different cell populations. In his animal cell culture research, he is active to increase the quality of therapeutic proteins. Lastly, he has a program in the stabilization of proteins using quantum mechanics to simulate various events leading to protein inactivation. His past research has been on new concepts in bioreactor design and operations, oxygen transfer in fermentors, fluid shear damage of animal cells, enzyme technology, membrane filtration and renewable resource utilization. His most recent research deals with biocatalysis in chiral chemical synthesis, renewable resource utilization for biofuels production and microbial desulfurization.
He has been the recipient of various awards. These include the elections to the National Academy of Engineering, American Academy of Arts and Sciences, American Institute of Biological Engineering, Academia Sinica (Republic of China) and the International Biotechnology Institute. He has received from the American Chemical Society the M.J. Johnson Award and Dave Perlman Memorial Lecture Award. From the American Institute of Chemical Engineers, he has received the Food, Pharmaceutical and Bioengineering Award, the Institute Lecturer and the William H. Walker Award. He has also received the Amgen Award from the Engineering Foundation and the Asia-Pacific Distinguished Biochemical Award. He has received honorary doctoral degrees from Hong Kong University of Science and Technology and Catholic University, Valparaiso, Chile and Honorary Professor from Peking Union Medical College. He has delivered plenary and keynote lectures throughout the world including Chile, England, Germany, Italy, Japan, Korea, Mexico, People’s Republic of China, New Zealand, Singapore and Taiwan.
He has co-authored 5 books, published over 250 papers, and secured 15 patents.
Noubar Afeyan, Ph.D.