mit che  
  department of chemical engineering
  Faculty, staff, students, post-docs, visitors
Chemical Engineering and the Department News, events and seminars Faculty, staff, students, post-docs, visitors Undergraduate program in ChE Graduate program in ChE Topics and people Careers and recruiting Resources for ChE faculty, staff and students
 
Faculty, staff, students, post-docs, visitors
faculty
staff
students
vistors/post-doc
back to
che
mit

Gregory Stephanopoulos
Selected Publications

Books

Isidore Rigoutsos and G. Stephanopoulos (eds.), “Systems Biology,” Volume 1 and 2, Oxford University Press, (2006)

G. Stephanopoulos (ed.) “Proceedings of the 1st Conference on Metabolic Engineering.”  Special Issue, Biotechnology & Bioengineering, Issues 2 & 3, (1998)

G. Stephanopoulos, Jens Nielsen, and A. Aristidou, “Metabolic Engineering. Principles and Methodologies”, Academic Press (1998)

G. Stephanopoulos (ed.), "Bioprocessing," Vol. 3 of Biotechnology, H. J. Rehm, G. Reed, A. Puhler, P. Stadler (series eds.), VCH, Weinheim (1993)

M.N. Karim and G. Stephanopoulos (eds.), "Modelling and Control of Biotechnical Processes," IFAC Symposia Series No. 10, Proceedings of the 5th Int. Conf. of Computer App. in Ferm. Tech., Keystone, CO, 29 March - 2 April 1992, Pergamon Press (1992)

H. W. Blanch, E. T. Papoutsakis and Gregory Stephanopoulos, (eds.) "Foundations of Biochemical Engineering, Kinetics and Thermodynamics of Biological Systems," ACS Symposium Series, 207 (1983)

Papers

H. Yu and G. Stephanopoulos, “Metabolic engineering of Escherichia coli for biosynthesis of hyaluronic acid,” Metabolic Engineering, 10: 24-32 (2008).

J.Y. Young, J.L. Walther, M.R. Antoniewicz, H.T. Yoo and G. Stephanopoulos, “An Elementary Metabolite Unit (EMU)-based method of isotopically instationary flux analysis,” Biotechnology & Bioengineering, 99: 686-699 (2008).

S. Biddinger, A. Hermanez-Ono, C. Rask-Madsen, J. Aleman, J. Haas, E. Scapa, C. Agarwal, M. Carey, G. Stephanopoulos, D. Cohen, G. King, H. Ginsberg and R. Kahn, “Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis,” Cell Metabolism, 7: 125-134 (2008).

G. Stephanopoulos, “Cellulosic biofuels,” Technology Review, January/February, p. 12 (2008).

Daniel Klein-Marcuschamer and G. Stephanopoulos, “Assessing the potential of mutational strategies to elicit new phenotypes in industrial strains,” Proceedings National Academy of Sciences, 105: 2319-2324 (2008).

C.N.S. Santos and Gregory Stephanopoulos, “Melanin-based high-throughput screen for L-tyrosine production in Escherichia coli,” Applied and Environmental Microbiology, 74: 1190-1197 (2008).

T. Lutke-Eversloh and G. Stephanopoulos, “Combinatorial pathway analysis for improved L-tyrosine production in Eschericjia coli: identification of enzymatic bottlenecks by systematic gene overexpression,” Metabolic Engineering, 10: 69-77 (2008).

P.K. Ajikumar, Keith Tyo, Simon Carlsen, Oliver Mucha, and G. Stephanopoulos, “Terpenoid natural products: a retrospect in the context of biosynthesis using engineered microorganisms,” Molecular Pharmaceutics, 5:167-190 (2008).

M. Styczynski, K. Jensen and G. Stephanopoulos, “Miscalculations in BLOSUM62 surprisingly improve search performance, Nature Biotechnology, 26: 274-275 (2008).

H. Alper and G. Stephanopoulos, “Uncovering the gene knockout landscape for improved lycopene production in E. coli,” Applied Microbiology & Biotechnology, 78: 801-810 (2008).

C.N.S. Santos and G. Stephanopoulos, “Combinatorial engineering of microbes for optimizing cellular phenotype,” Current Opinion in Chemical Biology, 12: 168-176 (2008).

C.R. Fischer, D. Klein-Marcuschamer and G. Stephanopoulos, “Selection and optimization of microbial hosts for biofuels production,” Metabolic Engineering, (in press) (2008).

H. Yu, K. Tyo, H. Alper, D. Klein-Marcuschammer and G. Stephanopoulos, “A high throughput screen for hyaluronic acid accumulation in recombinant Escherichia coli transformed by libraries of engineered sigma factors," Biotechnology & Bioengineering (in press) (2008).

Y.C. Tang, Heng-Phon Too and G. Stephanopoulos, “Information theoretic analysis of cell signaling identifies modulators of cell apoptotic response,” (submitted) (2008).

Further publications
< back to bio