skip to content

 

Departmental Resources: Careers


UROP Postings

The Department routinely receives notices of UROP opportunities and lists them here as a service to members of the MIT community. The positions have not been screened, nor verified to be available. Nor are they endorsed by the Department.

For more information, visit MIT's Undergraduate Research Opportunities Program (UROP).


UROP for fall 2015 semester
Faculty Supervisor: Dr. Alan Grodzinsky (alg@mit.edu)

Project Title: Evaluation of nanoparticles for drug delivery to cartilage

Description:
Osteoarthritis (OA) is the most common form of arthritis, affecting millions of people worldwide. The biggest challenge to treating OA is that cartilage (the affected tissue) does not have a blood supply, making it impossible to deliver drugs through intravenous or oral administration. Attempts have been made to administer drugs locally by injecting them into the joint space; but it has been found that these are rapidly cleared by the lymphatic system. Due to this large and frequent doses are required, which in turn can lead to adverse systemic side-effects. 

Our lab is working in collaboration with the Hammond lab to develop polymeric nanoparticle carriers for drug delivery to the cartilage. The goal is to develop a system that will make the drug available to the cartilage at low doses for long periods of time without being cleared away by the lymphatics. In this specific project, a UROP will be working with a graduate student to study the uptake and transport properties of different nanoparticles in cartilage. For the nanoparticles that show sufficient uptake, in-vitro toxicity tests will be conducted. The techniques that will be used include harvesting primary cartilage cells, spectrofluorometry, diffusivity measurement, cell culture techniques, fluorescence microscopy, and possibly confocal microscopy. No prior experience in any of these techniques is necessary. This is an interdisciplinary project and we invite undergraduates from a wide variety of disciplines including, but not restricted to, Chemical Engineering, Biological Engineering, Biology, Mechanical Engineering and Materials Science and Engineering.

Contact: Yamini Krishnan (yamini_k@mit.edu)

Posted: August 3, 2015


UROP for fall semester
MIT, Department of Chemical Engineering
Faculty Supervisor: Robert Langer

Project Title: Medical Device Design and Testing

Project Description: Our lab is focused on developing novel devices for healthcare and drug delivery. This particular project is based on the use of ultrasound for drug delivery. The goal of the project is to model and develop new ultrasound emission spectra for incorporation into a new device. Work will start with modeling and will involve fabrication and testing. Join a team that was a finalist in this year s MIT 100k Competition! 

What you will get out of it: 
-Work in an innovative, highly multi-disciplinary lab with state-of-the-art facilities and equipment. 
-Work closely with post-docs and advisors directly. 
-Potential for generation of intellectual property, exposure to patent process and business development 
-Team has a fast-paced startup feel

Prerequisites: A driven, enthusiastic, and collaborative student with modeling (COMSOL or other) experience. Someone who enjoys autonomy and tackling challenging, interdisciplinary work!

Contact:
 Carl Schoellhammer (cschoell@mit.edu)

Posted: July 24, 2015


UROP for fall semester
Prof. Karen Gleason Research Group
MIT, Department of Chemical Engineering

The goal for this research project is to develop thin film functional polymers using chemical vapor deposition technique for applications in energy and water systems. The synthesized films will be characterized using scanning electron microscopy (SEM), atomic force microscopy (AFM), Fourier transform infrared spectroscopy (FTIR), and ellipsometry among others. The UROP is expected to work closely with postdocs and graduate students and under direct supervision of the PI for the research group. A self-motivated individual with prior research experience who is likely pursue graduate studies is preferred. There will be lots of hands on experiments. Trainings will be provided as needed.

Contact: Hossein Sojoudi (hsojoudi@MIT.EDU)

Posted: July 21, 2015


UROP opportunities beginning August, 2015
Stephanopoulos Lab
MIT, Department of Chemical Engineering
Building 56-439
25 Ames Street
Cambridge, MA 02142

1) Engineering Thiobacillus denitrificans for production of bio-based chemicals. T. denitrificans is a sulfur-oxidizing chemolithoautroph in which we are interested for the potential to fix carbon dioxide into value-added chemicals. T. denitrificans is a biosafety level 1 bacteria which the student will learn to cultivate using standard microbiology techniques. Most of the day to day will involve media preparation, culturing, sampling, chromatography, and data analysis. There is potential for some cloning work in E. coli if the student is interested. T. denitrificans has a doubling time of 7 hours, so the student will likely be involved in the setup or workup, rather than the monitoring. We prefer the student is available for at least 2 hour blocks on consecutive days for this work.

2) Engineering E. coli for biofuel production from cellulosic sugars. This is a long-standing project in our lab, and we are always interested in UROP student involvement. There will be a lot more cloning in this project, so the student should be available for at least 3 - 5 hour blocks from Monday - Friday.

Contact: Jason King (j_king@mit.edu)

Posted: June 12, 2015