a  Main Menu

   Home
   Research
   Publications
   Personnel
   Alice Y. Ting
   Contact
   Intranet

 Additional Materials
 
   Plasmid distribution
   

Chemical approaches to the study of cell signaling

Welcome to our lab, located on the 4th floor of Building 18 in the Chemistry Department at MIT. Our research is centered on the development and application of technologies for uncovering molecular signaling events in living cells. In the past, we have developed methods for labeling specific proteins in living cells with chemical probes, imaged protein-protein interactions, imaged the activity of specific enzymes, and developed small and monovalent quantum dots for single protein imaging in live cells. Current work expands and extends these reporter classes using in vitro evolution methods and computational design. Furthermore, we are applying our enzyme engineering and organic synthesis capabilities to develop new methods for the proteomic analysis of living cells. To learn more...

Alice Y. Ting
Ellen Swallow Richards Professor
Department of Chemistry
Massachusetts Institute of Technology
Other affiliations:
Broad Institute, Koch Institute, MIT Biophysics, Picower Institute

Vicky's paper on APEX-mediated mapping of the mitochondrial intermembrane space proteome appears in Molecular Cell (7-3-2014)

Ozan selected for Charles A. King Trust postdoctoral fellowship (6-21-2014)

Former graduate student Sarah Slavoff to begin as assistant professor at Yale this summer (5-12-2014)

Monica receives Peter J. Eloranta Research Fellowship (5-8-2014)

APEX mapping method featured in NIH Director's blog (4-1-2014)

Faycal selected for HFSP cross disciplinary postdoctoral fellowship (3-18-2014)

Alice promoted to full professor (2-8-2014)

New graduate students Yisu and Tess join the lab (11-12-2013)

Philipp selected for Feodor Lynen Research Fellowship from the Humboldt Foundation (10-9-2013)

Our lab receives NIH Transformative Research Award (9-30-2013). MIT news article.

New postdocs Ozan Aygun and Faycal Touti join the lab (9-2013)

Philipp receives Simons (SCSB) postdoctoral fellowship (4-12-2013)

New postdoc Philipp Stawski joins the lab (4-1-2013)

Kurt receives NSF graduate research fellowship (3-29-2013)

Hyun-Woo and Peng's APEX proteomics paper highlighted in Nature Methods (3-28-2013)

Our lab receives a HFSP research grant, with Hayashi, Poncer, and de la Prida labs (3-19-2013)

Kayvon receives Simons Center for the Social Brain UROP funding (3-5-2013)

Monica is selected for the Amgen-UROP Scholars Program (3-1-2013)

Dan and Ken's paper "Imaging trans-cellular neurexin-neuroligin interactions by enzymatic probe ligation" appears in PLoS One (2-14-2013)

Hyun-Woo and Peng's paper "Proteomic mapping of mitochondria in living cells via spatially-restricted enzymatic tagging" appears in Science (1-31-2013). MIT news article.