Publications

An engineered aryl azide ligase for site-specific mapping of protein-protein interactions through photocrosslinking.
Angewandte Chemie International Edition 2008, early view online.
H. Baruah, S. Puthenveetil, Y.-A. Choi, S. Shah, and A. Y. Ting.

Protein-protein interaction detection in vitro and in cells by proximity biotinylation.
Journal of the American Chemical Society 2008, 130, 9251-9253.
M. Fernandez-Suarez, T. S. Chen, and A. Y. Ting



Monovalent, reduced-size quantum dots for imaging receptors on living cells.
Nature Methods 2008, 5, 397-399.
M. Howarth, W. Liu, S. Puthenveetil, Y. Zheng, L. F. Marshall, M. M. Schmidt, K. D. Wittrup, M. G. Bawendi, and A. Y. Ting.

Imaging proteins in live mammalian cells with biotin ligase and monovalent streptavidin.
Nature Protocols 2008, 3, 534-545.
M. Howarth and A. Y. Ting.



Compact biocompatible quantum dots functionalized for cellular imaging.
Journal of the American Chemical Society 2008, 130, 1274-1284.
W. Liu, M. Howarth, A. B. Greytak, Y. Zheng, D. G. Nocera, A. Y. Ting, and M. G. Bawendi.



Expanding the substrate tolerance of biotin ligase through exploration of enzymes from diverse species.
Journal of the American Chemical Society 2008, 130, 1160-1162.
S. A. Slavoff, I. Chen, Y.-A. Choi, and A. Y. Ting.



Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes.
Nature Biotechnology 2007, 25, 1483-1487.
M. Fernández-Suárez, H. Baruah, L. Martínez-Hernández, K. T. Xie, J. M. Baskin, C. R. Bertozzi, and A. Y. Ting.



Phage display evolution of a peptide substrate for yeast biotin ligase and application to two-color quantum dot labeling of cell surface proteins.
Journal of the American Chemical Society 2007, 129, 6619-6625.
I. Chen, Y.-A. Choi, and A. Y. Ting.



Synthesis of a ketone analog of biotin via the intramolecular Pauson-Khand reaction.
Organic Letters 2006, 8, 4593-4595.
E. McNeill, I. Chen, and A. Y. Ting.



Transglutaminase-catalyzed site-specific conjugation of small-molecule probes to proteins in vitro and on the surface of living cells.
Journal of the American Chemical Society 2006, 128, 4542-4543.
C.-W. Lin and A. Y. Ting.



A monovalent streptavidin with a single femtomolar biotin binding site.
Nature Methods 2006, 3, 267-273.
M. Howarth, D. J.-F. Chinnapen, K. Gerrow, P. C. Dorrestein, M. R. Grandy, N. L. Kelleher, A. El-Husseini, and A. Y. Ting.



Targeting quantum dots to surface proteins in living cells with biotin ligase.
Proceedings of the National Academy of Sciences 2005, 102, 7583-7588.
M. Howarth, K. Takao, Y. Hayashi, and A. Y. Ting.



Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase.
Nature Methods 2005, 2, 99-104.
I. Chen, M. Howarth, W. Lin, and A. Y. Ting.



A genetically encoded fluorescent reporter of histone phosphorylation in living cells.
Angewandte Chemie International Edition 2004, 43, 2940-2943.
C.-W. Lin and A. Y. Ting.



Genetically encoded fluorescent reporters of histone methylation in living cells.
Journal of the American Chemical Society 2004, 126, 5982-5983.
C.-W. Lin, C. Y. Jao, and A. Y. Ting.

 

Reviews

Next-generation optical technologies for illuminating genetically targeted brain circuits.
Journal of Neuroscience 2006, 26, 10380-10386.
K. Deisseroth, G. Feng, A. K. Majewska, G. Miesenbock, A. Y. Ting and M. J. Schnitzer.



Giving cells a new sugar-coating.
Nature Chemical Biology 2006, 2, 127-128.
M. Howarth and A. Y. Ting.



Site-specific labeling of proteins with small molecules in live cells.
Current Opinion in Biotechnology 2005, 16, 35-40.
I. Chen and A. Y. Ting.



Creating new fluorescent probes for cell biology.
Nature Reviews Molecular Cell Biology 2002, 3, 906-918.
J. Zhang, R. E. Campbell, A. Y. Ting and R. Y. Tsien.



Decoding NF-kB signaling.
Science 2002, 298, 1189-1190.
A. Y. Ting and D. Endy.

Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells.
Proceedings of the National Academy of Sciences 2001, 98, 15003-15008.
A. Y. Ting, K. H. Kain, R. L. Klemke, and R. Y. Tsien.



Phage-display evolution of tyrosine kinases with altered nucleotide specificity.
Biopolymers 2001, 60, 220-228.
A. Y. Ting, K. Witte, K. Shah, B. Kraybill, K. M. Shokat, and P. G. Schultz.



Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter.
Nature Neuroscience 2001, 4, 239-246.
T. Lu, A. Y. Ting, J. Mainland, L. Y. Jan, P. G. Schultz, and J. Yang.



Temporal fluctuations of fluorescence resonance energy transfer between two dyes conjugated to a single protein.
Chemical Physics 1999, 247, 107-118.
T. Ha, A. Y. Ting, J. Liang, A. A. Deniz, D. S. Chemla, P. G. Schultz, and S. Weiss.



Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism.
Proceedings of the National Academy of Sciences 1999, 96, 893-898.
T. Ha, A. Y. Ting, J. Liang, W. B. Caldwell, A. A. Deniz, D. S. Chemla, P. G. Schultz, and S. Weiss.



Energetic analysis of an engineered cation-pi interaction in staphylococcal nuclease.
Journal of the American Chemical Society 1998, 120, 7135-7136.
A. Y. Ting, I. Shin, C. Lucero, and P. G. Schultz.



Analysis of backbone hydrogen bonding in a ß-turn of staphylococcal nuclease.
Journal of the American Chemical Society 1997, 119, 12667-12668.
I. Shin, A. Y. Ting, and P. G. Schultz.



Improved enantioselective dihydroxylation of bishomoallylic alcohol derivatives using a mechanistically inspired bis-cinchona alkaloid catalyst.
Tetrahedron Letters 1996, 37, 1735-1738.
E. J. Corey, M. C. Noe, and A. Y. Ting.



Molecular cloning of a Schizosaccharomyces pombe cDNA encoding lanosterol synthase and investigation of conserved tryptophan residues.
Biochemical and Biophysical Research Communications 1996, 219, 327-331.
E. J. Corey, S. P. T. Matsuda, C. H. Baker, A. Y. Ting, and H. Cheng.



Markov random fields for text comprehension.
In D. Levine, M. Aparicio IV (eds.). Neural Networks for Knowledge Representation and Inference 1994, Hillsdale: NJ. Erlbaum, 283-298.
R. M. Golden, D. E. Rumelhart, J. Strickland, and A. Y. Ting.