Fu Group Project - Chiral Ligands

New Chiral Ligands for Transition Metal-Catalyzed Reactions

We have established that "planar-chiral" heterocycles can function as useful ligands in a wide array of transition metal-catalyzed reactions. These levels of stereoselectivity represent the state-of-the-art for these processes.

• asymmetric coupling of alkynes with nitrones

• enantioselective hydrosilylation of ketones

• asymmetric isomerization of allylic alcohols

Selected Publications

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List of publications by date

List of publications by project

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		Catalytic Enantioselective O-H Insertion Reactions
		J. Am Chem. Soc. 2005, 128, 4594-4595.
		Maier, T. C.; Fu, G. C.

		Kinetic Resolutions of Azomethine Imines via Copper-Catalyzed [3+2] Cycloadditions
		J. Am Chem. Soc. 2005, 127, 11244-11245.
		Suárez, A.; Downey, C. W.; Fu, G. C.

		A New Copper-Catalyzed [3 + 2] Cycloaddition: Enantioselective Coupling of Terminal Alkynes with Azomethine Imines to Generate Five-Membered Nitrogen Heterocycles
		J. Am Chem. Soc. 2003, 125, 10778-10779.
		Shintani, R.; Fu, G. C.

		Catalytic Enantioselective Synthesis of ß-Lactams: Intramolecular Kinugasa Reactions and Interception of an Intermediate in the Reaction Cascade
		Angew. Chem. Int. Ed. 2003, 42, 4082-4085.
		Shintani, R.; Fu, G. C.

		Application of a New Family of P,N-Ligands to the Highly Enantioselective Hydrosilylation of Aryl Alkyl and Dialkyl Ketones
		Angew. Chem. Int. Ed. 2002, 41, 3892-3894.
		Tao, B.; Fu, G. C.

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Download PDFs: Curriculum Vitae • Publications by Date • Publications by Project

Project Pages: Nucleophilic Catalysis • Chiral Ligands • Palladium and Nickel Catalysis • Boron Heterocycles

Other Pages: Home • About Greg Fu • Group Members • Photos

Professor Gregory C. Fu
Department of Chemistry • Massachusetts Institute of Technology
77 Massachusetts Avenue, Room 18-290
Cambridge, MA 02139-4307 USA

(617) 253-2664 • fax: (617) 324-3611

email: gcf@mit.edu

This site was last updated on January 23, 2008