The Jamison Research Group


Doris Lee

  Massachusetts Institute of Technology, 2013 - present
Postdoctoral Fellow with Professor Timothy F. Jamison
Ph.D. University of Toronto, Canada, 2013
"Boron–Diol Interactions as the Basis for Novel Catalytic Transformations"
with Prof. Mark S. Taylor
B.Sc. University of Ottawa, Canada, 2008
with Prof. Keith Fagnou

Current Research:
    Compact, On-Demand Continuous Flow Manufacturing of Pharmaceuticals

  • Ocampo, C.E.; Lee, D; Jamison, T.F. "Selective Lewis Acid Catalyzed Assembly of Phosphonomethyl Ethers: Three-Step Synthesis of Tenofovir" Org. Lett. 2015, 17, 820-823.
  • Lee, D.; Taylor, M. S. “Regioselective Silylation of Pyranosides Using a Boronic Acid / Lewis Base Co-Catalyst System.” Org. Biomol. Chem. 2013, 11, 5409–5412.
  • Lee, D.; Taylor, M. S. “Catalyst-Controlled Regioselective Reactions of Carbohydrate Derivatives.” Synthesis 2012, 44, 3421–3431 (Short Review, Invited Article).
  • Lee, D.; Williamson, C. L.; Chan, L.; Taylor, M. S. “Regioselective, Borinic Acid-Catalyzed Monoacylation, Sulfonylation and Alkylation of Diols and Carbohydrates: Expansion of Substrate Scope and Mechanistic Studies.” J. Am. Chem. Soc. 2012134, 8260–8267.
  • Gouliaras, C.; Lee, D.; Chan, L.; Taylor, M. S. “Regioselective Activation of Glycosyl Acceptors by a Diarylborinic Acid-Derived Catalyst.” J. Am. Chem. Soc2011133, 13926–13929.
  • Lee, D.; Taylor, M. S. “Borinic Acid-Catalyzed Regioselective Acylation of Carbohydrate Derivatives.” J. Am. Chem. Soc. 2011133, 3724–3727.
  • Beaulieu, C.; Isobel, E.; Fortier, A.; Massé, F.; Mellon, C.; Méthot, N.; Ndao, M.; Nicoll-Griffith, D.; Lee, D.; Park, H.; Black, W. C. “Identification of Potent and Reversible Cruzipain Inhibitors for the Treatment of Chagas Disease.” Bioorg. Med. Chem. Lett. 201020, 74447449.
  • Lee, D.; Newman, S. G.; Taylor, M. S. “Boron-Catalyzed Direct Aldol Reactions of Pyruvic Acids.” Org. Lett. 200911, 54865489.
  • Liégault, B.; Lee, D.; Huestis, M. P.; Stuart, D. R.; Fagnou, K. “Intramolecular Pd(II)-Catalyzed Oxidative Biaryl Synthesis Under Air: Reaction Development and Scope.” J. Org. Chem. 200873, 50225028.
    d_lee at mit dot edu