The Jamison Research Group

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Kim Lebek Jensen

Education:
  Massachusetts Institute of Technology, 2013 - present
Postdoctoral Fellow with Professor Timothy F. Jamison
  Aarhus University, 2012
Postdoctoral Associate with Professor Karl Anker Jørgensen
Ph.D. Aarhus University 2012
“Asymmetric Organocatalysis in One-Pot and Dual Activation Strategies for the Synthesis of Carbo- and Heterocyclic Compounds”
with Prof. Karl Anker Jørgensen
B.Sc. Aarhus University, 2007
with Prof. Troels Skrydstrup

Current Research:
    Nickel Catalysis

Publications:
  • Jensen, K.L.; Standley, E.A.; Jamison, T.F. "Highly Regioselective Nickel-Catalyzed Cross-Coupling of N-Tosylaziridines and Alkylzinc Reagents" J. Am. Chem. Soc. 2014, 136, 11145-11152.
  • Jiang, H.; Albrecht, Ł.; Dickmeiss, G.; Jensen, K. L.; Jørgensen, K. A. “Silyl-Protected Diarylprolinol Catalysts in Organocatalysis” Book chapter in Comprehensive Enantioselective Organocatalysis (Wiley-VCH, Weinheim), In Press.
  • Jensen, K. L.; Weise, C. F.; Dickmeiss, G.; Morana, F.; Davis, R. L.; Jørgensen, K. A. “Accessing Both Diastereoisomers Selectively in an Enantioselective, Intramolecular Michael Reaction Using a Single Chiral Organocatalyst and Formal Total Synthesis of (−)-Epibatidine”Chem. Eur. J.. 2012, 18, 11913.
  • Jensen, K. L.; Poulsen, P. H.; Donslund, B. S.; Morana, F.; Jørgensen, K. A. “Asymmetric Synthesis of γ-Nitroesters by an Organocatalytic One-Pot Strategy”Org. Lett. 2012, 14, 1516.
  • Steurer M.; Jensen, K. L.; Worgull D.; Jørgensen, K. A. “Enantioselective One-Pot Synthesis of α-Amino Esters by a Phosphine-Catalyzed [3+2]-Cycloaddition Reaction”Chem. Eur. J. 2012, 18, 76.
  • Jensen, K. L.; Dickmeiss; G.; Jiang, H.; Albrecht, Ł.; Jørgensen, K. A. “The Diarylprolinol Silyl Ether System: A General Organocatalyst”Acc. Chem. Res.. 2012, 45, 248.
  • Jacobsen, C. B.; Jensen, K. L.; Udmark, J.; Jørgensen, K. A. “Organocatalytic Iminium Ion/Carbene Reaction Cascade for the Formation of Optically Active 2,4-Disubstituted Cyclopentenones”Org. Lett.. 2011, 13, 4790.
  • Jensen, K. L.; Dickmeiss; G.; Donslund, B. S.; Poulsen, P. H.; Jørgensen, K. A. “Asymmetric Organocatalytic Synthesis of Complex Cyclopenta[b]quinoline Derivatives” Org. Lett.. 2011, 13, 3678.
  • Worgull, D.; Dickmeiss; G.; Jensen, K. L.; Franke, T. P.; Holub, N.; Jørgensen, K. A. “Optically Active Bicyclic N-Heterocycles by Organocatalytic Asymmetric Michael Addition/Cyclization Sequences” Chem. Eur. J.. 2011, 17, 4076.
  • Monge, D.; Jensen, K. L.; Marín, I.; Jørgensen, K. A. “Synthesis of 1,2,4-Triazolines: Base-Catalyzed Hydrazination/Cyclization Cascade of α-Isocyano Esters and Amides” Org. Lett.. 2011, 13, 328.
  • Dickmeiss; G.; Jensen, K. L.; Worgull, D.; Franke, T. P.; Jørgensen, K. A. “An Asymmetric Organocatalytic One-Pot Strategy to Octahydroacridines”Angew. Chem. Int. Ed.. 2011, 50, 1580.
  • Monge, D.; Jensen, K. L.; Franke, T. P.; Lykke, L.; Jørgensen, K. A. “Asymmetric One-Pot Sequential Organo- and Gold Catalysis for the Enantioselective Synthesis of Dihydropyrrole Derivatives”Chem. Eur. J.. 2010, 16, 9478.
  • Jensen, K. L.; Franke, P. T.; Arróniz, C.; Kobbelgaard, S.; Jørgensen, K. A. “Enantioselective Synthesis of Cyclopentene Carbaldehydes by a Direct Multicatalytic Cascade Sequence: Carbocyclization of Aldehydes with Alkynes” Chem. Eur. J.. 2010, 16, 1750.
  • Jensen, K. L.; Franke, P. T.; Nielsen, L. T.; Daasbjerg, K.; Jørgensen, K. A. “Anodic Oxidation and Organocatalysis: Direct Regio- and Stereoselective Access to meta-Substituted Anilines by a-Arylation of Aldehydes” Angew. Chem. Int. Ed.. 2010, 49, 129.
  • Jiang, H.; Elsner, P.; Jensen, K. L.; Falcicchio, A.; Marcos, V.; Jørgensen, K. A. “Achieving Molecular Complexity by Organocatalytic One-Pot Strategies—A Fast Entry for Synthesis of Sphingoids, Amino Sugars, and Polyhydroxylated α-Amino Acids” Angew. Chem. Int. Ed.. 2009, 48, 6844.
  • Jiang, H.; Falcicchio, A.; Jensen, K. L.; Paixão, M. W.; Bertelsen, S.; Jørgensen, K. A. “Target-Directed Organocatalysis: A Direct Asymmetric Catalytic Approach to Chiral Propargylic and Allylic Fluorides” J. Am. Chem. Soc.. 2009, 131, 7153.
  • Gøgsig, T. M.; Søbjerg, L. S.; Lindhardt, A. T.; Jensen, K. L.; Skrydstrup, T. “Direct Vinylation and Difluorovinylation of Arylboronic Acids Using Vinyl- and 2,2-Difluorovinyl Tosylates via the Suzuki-Miyaura Cross Coupling”J. Org. Chem.. 2008, 73, 3404.

Contact:
    kimlebek at mit dot edu