The Jamison Research Group

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Leandro Helgueira de Andrade

Education:
  Massachusetts Institute of Technology, 2013 - present
Visiting Scientsist with Professor Timothy F. Jamison
Associate Professor University of São Paulo, 2013
Assistant Professor University of São Paulo, 2008
Postdoctoral Fellow University of São Paulo, 2003
with Prof. J.V. Comasseto
Ph.D. Federal University of Santa Maria (RS, Brazil), 2002
"Synthesis of vinyl-/enyl- phosphonates and synthetic application of chiral imidazolidine disulfides in asymmetric reactions"
with Prof. A.L. Braga
M.S. Federal University of Santa Maria (RS, Brazil), 1998
"Stereoselective addition of sodium organyl chalcogenolates to alkynylphosphonates: synthesis of diethyl 2-(organyl)-2-(organochalcogenyl)vinylphosphonates"
with Prof. A.L. Braga
B.S. Federal University of Santa Maria, 1996

Current Research:
    Enzymatic Transformations in Continuous Flow Synthesis

Publications:
  • Netto, C. G.C.M.; Toma, H. E.; Andrade, L. H. Superparamagnetic nanoparticles as versatile carriers and supporting materials for enzymes, J. Mol. Catal. B: Enz., 2013, 85-86, 71.
  • Brondani, P. B.; Dudek, H.; Reis, J. S.; Fraaije, M. W.; Andrade, L. H. Exploiting the enantioselectivity of Baeyer-Villiger monooxygenases via boron oxidation, Tetrahedron: Asymmetry, 2012, 23, 703.
  • Piovan, L.; Alves, M. F. M.; Juliano, L.; Bromme, D.; Cunha, R. L. O. R.; Andrade, L. H. Structure activity relationships of hypervalent organochalcogenanes as inhibitors of cysteine cathepsins V and S, Bioorg. Med. Chem., 2011, 19, 2009-2014.
  • Araújo, L. S.; Kagohara, E.; Garcia, T. P.; Pellizari, V. H.; Andrade, L. H. Screening of Microorganisms Producing Cold-Active Oxidoreductases to Be Applied in Enantioselective Alcohol Oxidation. An Antarctic Survey, Marine Drugs 2011, 9, 889.
  • Brondani, P. B.; Gonzalo, Gonzalo de; Fraaije, M. W.; Andrade, L. H. Selective Oxidations of Organoboron Compounds Catalyzed by Baeyer-Villiger Monooxygenases, Adv. Synth. Catal., 2011, 353, 2169.
  • Andrade, L. H.; Silva; A. V.; Milani, P.; Koszelewski, D.; Kroutil, W. Transaminases as efficient biocatalysts to obtain novel chiral selenium-amine ligands for Pd-catalysis, Org. Biomol. Chem., 2010, 8, 2043.
  • Andrade, L. H.; Barcellos, T. Lipase-catalyzed highly enantioselective kinetic resolution of boron-containing chiral alcohols, Org. Lett. 2009, 14, 3052.
Contact:
    leandroh at mit dot edu
    leandroh at ip dot usp dot br
Information:
    http://www2.iq.usp.br/biocatalise/Biocatalise