The Jamison Research Group

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Oleg Vechorkin

Education:
  Massachusetts Institute of Technology, 2011 - present
NSF Postdoctoral Fellow with Prof. Timothy F. Jamison/td>
Ph.D. Swiss Federal Institute of Technology, Lausanne, 2011
"A Well-defined Ni Pincer Catalyst for Cross Coupling of non-Activated Alkyl Halides and Direct C-H Alkylation"
with Prof. Xile Hu
M.S. Kharkov National University, Ukraine, 2007
"Simulation of Solid State Reactions in Terms of Tiling"
with Prof. Alexander Korobov

Current Research:
    Epoxide-opening cascades in the total synthesis of marine ladder polyether natural products

Publications:
  • Vechorkin, O.; Hu X. L. “Bis[(2-dimethylamino)phenyl]amine Nickel(II) Chloride” e-EROS, Encyclopedia of Reagents for Organic Synthesis. Wiley, 2011.
  • Ren, P.; Vechorkin, O.; von Allmen, K.; Scopelliti, R.; Hu,X. L. “A Structure-Activity Study of Ni-Catalyzed Alkyl-Alkyl Kumada Coupling. Improved Catalysts for Coupling of Secondary Alkyl Halides” J. Am. Chem. Soc. 2011, 133, 7084-7095.

  • Ren, P.; Vechorkin, O.; Csok, Z.; Salihu, I.; Scopelliti, R.; Hu,X. L. “Pd, Pt, and Ru complexes of a pincer bis(amino)amide ligand” Dalton Transactions 201140, 8906-8911. 

  • Vechorkin, O.; Hirt, N.; Hu, X. L. “Carbon Dioxide as the C-1 Source for Direct C-H Functionalization of Aromatic Heterocycles” Org. Lett. 2010, 12, 3567-3569.

  • Breitenfeld, J.; Vechorkin, O.; Corminboeuf, C.; Scopelliti, R.; Hu, X. L. “Why Are (NN2)Ni Pincer Complexes Active for Alkyl-Alkyl Coupling: ß-H Elimination is Kinetically Accessible but Thermodynamically Uphill” Organometallics 2010, 29, 3686-3689.
  • Vechorkin, O.; Proust V.; Hu, X. L. “The Ni/Cu-Catalyzed Direct Alkylation of Heterocyclic C-H Bonds” Angew. Chem., Int. Ed. 2010, 49, 3061-3064.
  • Vechorkin, O.; Barmaz, D.; Proust V.; Hu, X. L. “Ni-Catalyzed Sonogashira Coupling of Non-activated Alkyl Halides: Orthogonal Functionalization of Alkyl Iodides, Bromides, and Chlorides” J. Am. Chem. Soc. 2009131, 12078-12079.
  • Vechorkin, O.; Proust V.; Hu, X. L. “Functional Group Tolerant Kumada-Corriu-Tamao Coupling of Nonactivated Alkyl Halides with Aryl and Heteroaryl Nucleophiles: Catalysis by a Nickel Pincer Complex Permits the Coupling of Functionalized Grignard Reagents” J. Am. Chem. Soc. 2009131, 9756-9766.
  • Vechorkin, O.; Hu, X. L. “Nickel-Catalyzed Cross-Coupling of Non-activated and Functionalized Alkyl Halides with Alkyl Grignard Reagents” Angew. Chem., Int. Ed. 2009, 48, 2937-2940.
  • Vechorkin, O.; Csok, Z.; Scopelliti, R.; Hu, X. L. “Nickel Complexes of a Pincer Amidobis(amine) Ligand: Synthesis, Structure, and Activity in Stoichiometric and Catalytic C-C Bond Forming Reactions of Alkyl Halides” Chem. Eur. J. 2009, 15, 3889-3899.
  • Csok, Z.; Vechorkin, O.; Harkins, S. B.; Scopelliti, R.; Hu, X. L. “Nickel Complexes of a Pincer NN2 Ligand: Multiple Carbon-Chloride Activation of CH2Cl2 and CHCl3 Leads to Selective Carbon-Carbon Bond Formation” J. Am. Chem. Soc. 2008, 130, 8156-8157.

Contact:
    olegv at mit dot edu