The Jamison Research Group

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Yuan Zhang

Education:
  Massachusetts Institute of Technology, 2011 - present
Postdoctoral Associate with Professor Timothy F. Jamison
Ph.D. University of Utah, 2011
"Rapid construction of polycyclic ether skeletons using two-directional olefinic ester cyclization; total synthesis of (-)-brevenal and efforts towards the synthesis of yessotoxin and adriatoxin"
with Prof. Jon D. Rainier
M.S. Nanjing University, 2005
with Prof. Jian-xin Li
B.S. Nanjing University, 2002
with Prof. Yi Pan

Current Research:
    MIT-Novartis Collaboration

Publications:
  • Zhang, Y.; Rohanna, J. C.; Zhou, J.; Iyer, K.; Rainier, J. D. “Total Synthesis of (-)-Brevenal” J. Am. Chem. Soc. 2011, 133, 3208.
  • Zhang, Y.; Rainier, J. D. “Two-Directional Olefinic-Ester Ring-Closing Metathesis Using Reduced Ti Alkylidenes. A Rapid Entry into Polycyclic Ether Skeletons” Org. Lett. 2009, 11, 237.

  • Zhang, Y.; Li, J.-X.; Zhao, J.; Wang, S.-Z.; Pan, Y.; Tanaka, K.; Kadota, S. “Synthesis and Activity of Oleanolic Acid Derivatives, a Novel Class of Inhibitors of Osteoclast Formation” Bioorg. Med. Chem. Lett. 2005, 15, 1629.

  • Li, J.-X.; Hareyama, T.; Tezuka, Y.; Zhang, Y.; Miyahara, T.; Kadota, S. “Five New Oleanolic Acid Glycosides from Achyranthes Bidentata with Inhibitory Activity on Osteoclast Formation” Planta Med. 2005, 71, 673.

Contact:
    yzhangut at mit dot edu