Jamison Group at MIT

 

 

 

 

 

 
Denise Colby

Education:

  Massachusetts Institute of Technology, 2009 - present
NIH postdoctoral fellow
postdoctoral associate with Prof. Timothy F. Jamison
Ph.D.

University of California Berkeley, 2008
"Synthetic and Mechanistic Investigations of Transformations
Proceeding via Chelation-Assisted C-H Bond Activation"
with Prof. Robert G. Bergman and Prof. Jonathan A. Ellman
B.S.

Illinois State University, 2004
with Prof. Timothy D. Lash

Current research:

Applying epoxide-opening cascades to the total synthesis of ladder polyethers.
 

Publications:

  • Denise A. Colby, Robert G. Bergman, Jonathan A. Ellman. “Synthesis of Dihydropyridines and Pyridines from Imines and Alkynes via C-H Activation” J. Am. Chem. Soc. 2008, 130, 3645-3651.

  • Timothy D. Lash, Denise A. Colby, Aparna S. Idate, Randall N. Davis. “Fulvene Dialdehyde Strategy for adj-Dicarbaporphyrinoid Synthesis: Preparation of a 22-Carbaazuliporphyrin” J. Am. Chem. Soc. 2007, 129, 13800-13801.

  • Denise A. Colby, Robert G. Bergman, Jonathan A. Ellman. “Stereoselective Alkylation of alpha,beta-Unsaturated Imines via C-H Bond Alkylation” J. Am. Chem. Soc. 2006, 128, 5604-5605.

  • Denise A. Colby, Gregory M. Ferrence, Timothy D. Lash. “Oxidative Metalation of Azuliporphyrins with Copper(II) Salts: Formation of a Porphyrin Analogue System with a Unique Fully Conjugated Nonaromatic Azulene Subunit” Angew. Chem. Int. Ed. Eng. 2004, 43, 1346-1349.

  • Timothy D. Lash, Denise A. Colby, Shelley R. Graham, Sun T. Chaney. “Synthesis, Spectroscopy, and Reactivity of meso-Unsubstituted Azuliporphyrins and Their Heteroanalogues. Oxidative Ring Contractions to Carba-, Oxacarba-, Thiacarba-, and Selenacarbaporphyrins” J. Org. Chem. 2004, 69, 8851-8864.

  • Timothy D. Lash, Denise A. Colby, Lisa F. Szczepura. “New Riches in Carbaporphyrin Chemistry: Silver and Gold Organometallic Complexes of Benzocarbaporphyrins” Inorg. Chem. 2004, 23, 5258-5267.

  • Timothy D. Lash, Jane. M. Rasmussen, Katrina M. Bergman, Denise A. Colby. “Carbaporphyrinoid Chemistry has a Silver Lining! Silver(III) Oxybenzi-, Oxynaphthi-, Tropi-, and Benzocarbaporphyrins” Org. Lett. 2004, 6, 549-552.

  • Timothy D. Lash, Denise A. Colby, Shelley R. Graham, Gregory M. Ferrence, Lisa F. Szczepura. “Organometallic Chemistry of Azuliporphyrins: Synthesis, Spectroscopy, Electrochemistry, and Structural Characterization of Nickel(II), Palladium(II), and Platinum(II) Complexes of Azuliporphyrins” Inorg. Chem. 2003, 42, 7326-7338.

  • Timothy D. Lash, Denise A. Colby, Gregory M. Ferrence. “Further Studies on the Synthesis of meso-Tetraarylazuliporphyrins under Lindsey-Rothemund Reaction Conditions and Their Conversion into Benzocarbaporphyrins” Eur. J. Org. Chem. 2003 4533-4548.

  • Shelley R. Graham, Denise A. Colby, Timothy D. Lash. “An Azulene Analogue of the Tripyrranes and Carbaporphyrins Therefrom” Angew. Chem. Int. Ed. Eng. 2002, 41, 1371-1374.

  • Denise A. Colby, Timothy D. Lash, “Adaptation of the Rothemund Reaction for Carbaporphyrin Synthesis: Preparation of meso­-Tetraphenylazuliporphyrin and Related Benzocarbaporphyrins” Chem. Eur. J. 2002, 8, 5397-5402.
    Denise A. Colby, Timothy D. Lash. “Calix[4]azulene” J. Org. Chem. 2002, 67, 1031-1033.