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Prakash Palde |
Education:
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Massachusetts Institute of Technology, 2009 - present
postdoctoral fellow with Prof. Timothy F. Jamison |
| Ph.D. |
University of Rochester,, 2009
“Exploring Small Molecules as Receptors in Carbohydrate Recognition and as Ligands Targeting RNA Sequences Relevant to HIV-1.”
with Professor Benjamin L. Miller
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| M.S. |
National Institute of Pharmaceutical Education and Research (NIPER), India
“Anti-tuberculosis Agents: Synthesis and Biological Evaluation of Quinoline-4-Acetic Acid Derivatives.
with Professor Rahul Jain
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Other experience:
Senior Chemist at Dr. Reddy’s Laboratories Ltd., India, 2001-2003. |
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Current research:
MIT-Novartis collaboration. |
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Publications:
- Palde, P. B.; Gareiss, P. C.; Miller, B. L. Selective Recognition of Alkyl Pyranosides in Protic and Aprotic Solvents. J. Am. Chem. Soc. 2008, 130, 9566-9573.
- Gareiss, P. C.; Sobczak, K.; McNaughton, B. R.; Palde, P. B.; Thornton, C. A.; Miller, B. L. Dynamic Combinatorial Selection of Molecules Capable of Inhibiting the (CUG) Repeat RNA – MBNL1 Interaction in vitro: Discovery of Lead Compounds Targeting Myotonic Dystrophy (DM1). J. Am. Chem. Soc. 2008, 130, 16254-16261.
- Palde, P. B.; McNaughton, B. R.; Ross, N. T.; Gareiss, P. C.; Mace, C. R.; Spitale, R. C.; Miller, B. L. Single-Step Synthesis of Functional Organic Receptors via a Tridirectional Minisci Reaction. Synthesis 2007, 15, 2287-2290.
- Gareiss, P. C.; Palde, P. B.; Hubbard, R. D.; Miller, B. L. Conformational and Structural Analysis of a ter-Cyclopentane Scaffold for Molecular Recognition. Eur. J. Org. Chem. 2007, 1, 53-61.
- Monga, V.; Nayyar, A.; Vaitilingam, B.; Palde, P. B.; Jambh, S. S.; Kaur, S.; Singh, P. P.; Jain, R. Ring-substituted quinolines. Part 2: Synthesis and Antimycobacterial Activities of Ring-Substituted Quinolinecarbohydrazide and Ring-Substituted Quinolinecarboxamide Analogues. Bioorg. Med. chem. 2004, 24, 6465-6472.
- Vaitilingam, B.; Nayyar, A.; Palde, P. B.; Monga, V.; Jain, R.; Kaur, S.; Singh, P. P. Synthesis and Antimycobacterial Activities of Ring-Substituted Quinolinecarboxylic Acid/Ester Analogues. Part 1. Bioorg. Med. Chem. 2004, 12, 4179-4188.
- Jain, R.; Vaitilingam, B.; Nayyar, A.; Palde, P. B. Substituted 4-Methylquinolines as a New Class of Anti-Tuberculosis Agents. Bioorg. Med. Chem. Lett. 2003, 13, 1051-1054.
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