ChemformationChemformation
Volume 15, Number 11
Friday, March 26, 1999
Chemformation is published by the Office of the Department Chairman. Please convey items of interest (or mailing list changes) to Linda Earle, Room 18-390, Department of Chemistry, MIT, Cambridge, MA 02139, 617/253-4080; 617/258-7500 (fax) or e-mail to lkn@mit.edu. Back issues of Chemformation can be accessed via the Chemistry Department Website.
Visit the Chemistry Department Website at http://web.mit.edu/chemistry/www/
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Tuesday, April 13, 1999 4:00 p.m. in Room 2-105 Seminar in Physical Chemistry Refreshments @ 3:30 in Room 6-233 |
Professor John Fourkas Boston College "Probing the Microscopic Dynamics of Liquids and the Dynamics of Microscopic Liquids" |
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Wednesday, April 14, 1999 4:00 p.m. in Room 6-120 Seminar in Inorganic Chemistry Refreshments @ 3:30 p.m. |
Silvia T. Hoehn Stubbe Group "Bleomycin: Structure and Function" |
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Thursday, April 15, 1999 4:00 p.m. in Room 6-120 Seminar in Biological Chemistry Refreshments @ 3:45 p.m. |
Dr. Gabriele Varani MRC Laboratory of Molecular Biology, Cambridge, UK "RNA-Protein Intermolecular Recognition" |
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Thursday, April 22, 1999 5:00 p.m. in MB23 Harvard MIT Physical Chemistry Seminar at Harvard Refreshments @ 4:30 p.m. in MB23 |
Professor Robert J. Silbey Mass. Institute of Technology "Spectroscopy in Low Temperature Solids: Photon Echos, Hole-Burning and Single Molecule Spectroscopy" |
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Tuesday, April 27, 1999 9:30 a.m. in Room 6-120 Chemistry 5.561 Chemistry in Industry Lecture Series |
Dr. Robert A. Volkmann Pfizer Central Research "Discovery of an Amino Acid Peptide Isomerase" |
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Tuesday, April 27, 1999 4:00 p.m. in Room 2-105 Seminar in Physical Chemistry Refreshments @ 4:00 p.m. in 6-233 |
Professor Michael Fayer Stanford University "Protein Dynamics: Ultrafast Infrared Vibrational Echo Experiments |
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Wednesday, April 28, 1999 4:00 p.m. in Room 6-120 Seminar in Inorganic Chemistry Refreshments @ 3:30 p.m. |
Ann Jones Davison Group "Rhenium and Technetium Coordination Chemistry: Applications in Radiopharmaceuticals |
Massachusetts Institute of Technology
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| April 27 |
Dr. Robert A. Volkmann Senior Research Fellow Pfizer Central Research "Discovery of an Amino Acid Peptide Isomerase" |
| May 4 |
Dr. Jeffrey H. Epstein-Toney Research Fellow in Endocrinology & Chemical Biology Merck Research Laboratories "Merck's Armament Against Antibiotic Resistance: A Chemical Biology Approach " |
| May 6 |
Dr. Steven A. King Project Leader, Department of Process Research Abbott Laboratories "Diastereo- and Enantioselective Synthesis of Highly Substituted Pyrrolidines Leading to Potent Endothelin Antagonists" |
| May 11 |
Dr. Kevin Chapman Senior Director, Medicinal Chemistry Merck Research Laboratories "Combinatorial Approaches to the Somatostatin Family of Receptors" |
Massachusetts Institute of Technology
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Marc L. Snapper Boston College |
"New Strategies for the Synthesis of Biological Probe Reagents" |
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Rick L. Danheiser Massachusetts Institute of Technology |
"Studies Directed Toward the Total Synthesis of Glycinoeclepin A" |
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Stephen F. Martin University of Texas, Austin |
"Recent Advances in the Synthesis of Heterocyclic Natural Products" |
Call Ed Udas at 253-4505 or stop by room 4-065 if students, faculty, or staff need help in organizing their MIT space.
Bob DiGiacomo will be coming in on Wednesdays or Thursdays to pick up any glass blowing work that you may have available. Please bring any work to room 4-064 or call Ed Udas or John Annese at 3-4505. Bob will do the work on a first-come, first-served basis.
Mississippi State University, Starkville, MS: Postdoctoral position in laser spectroscopy available in molecular laser spectroscopy at Mississippi State University¼s Diagnostic Instrumentation and Analysis Laboratory (DIAL). DIAL is a multidisciplinary research institute, funded predominately by the Department of Energy. The major emphasis of their research programs concerns application of modern instrumentation including lasers to environmental, combustion and propulsion problems. The research associate will work on application of laser spectroscopy (especially cavity ring-down spectroscopy, photoionization/time-of-flight mass spectrometry, and laer-induced fluorescence) to environmental and combustion problems. Fax materials or email to: Dr. R. Vasudev, Mississippi State University, Diagnostic Instrumentation and Analysis Laboratory, 205 Research Blvd. Research and Technology Park, Starkville, MS 39759-9734; Fax (601) 325-84365; email: vasudev@dial.msstate.edu
TechFind, Natick, MA: Has a client seeking a Director of Product Development, drug reformation for a unique use. 1. Oversee development and validation of analytical methods, 2. Oversee development and formulation of pharmaceutical dosage forms, tablets, capsules, liquid orals and parenterals, 3. Oversee analytical method development and documentation for NDA submissions, 4. Evaluate site of manufacture and scale up production. Requirements a Ph.D. in pharmacy and prefer 7-10 years experience. Contact: Carol Butler, TechFind, (508) 647-0111, cb@techfind.com
Phylos, Inc. is a young, well-funded biotechnology company dedicated to the development and application of the emerging technology of directed protein evolution. Molecular, Cellular and Protein Biology and Antibody Engineering; MS/BS Job: 50-2 We are seeking highly motivated scientist's to join our Molecular Biology, Cell Biology, and Protein Biochemistry Departments. To fill this broad area of scientific interest, we are looking for a number of candidates with expertise in several of the following disciplines: vector construction, prokaryotic and eukaryotic cell growth, SELEX, and PCR. Candidates with antibody engineering and immunoassay experience are highly preferred. Synthetic Organic Chemist; Research Scientist: BS/MS Job Code: 52-1 You will be responsible for the synthesis, purification and characterization of novel compounds. Proficiency in organic synthesis and spectroscopic techniques is required. Experience in nucleic acid and/or peptide chemistry is a plus. Minimum qualifications include a BS degree in Chemistry and 1-3 year of laboratory experience.Protein Biochemistry Ò Protein Production Ph.D Job Code: 53-1, BS/MS: Job Code 53-2 You will optimize expression of target proteins in heterologous systems, develop purification procedures, and purify proteins on a milligram to gram scale. Extensive experience with gene cloning from cDNA libraries, vector construction, a variety of prokaryotic and eukaryotic expression systems, as well as standard and high performance chromatography and protein characterization methods, is required. Further experience in molecular biology, protein refolding, protein immobilization, analysis of protein-protein interaction, and familiarity with the correlation between macromolecular structure and function are highly desirable. The Ph.D position requires excellent organizational skills and some supervisory experience. Candidates for both positions need to work well independently as well as in close interdepartmental collaboration. Microchip Biology/Chemistry Scientist Research Scientist: BS/MS: Job Code: 52-3 You will join an interdisciplinary team developing novel Protein Display Microchips. Familiarity with basic molecular biology and/or surface derivatization techniques is required. Exposure to micorarray technology, high-throughput screening, RNA manipulation, hybridization, robotic systems, immunoassay, or fluorescence is a plus. Minimum qualifications include a BS degree in a biological or chemistry science and 1-3 years of laboratory experience.
Executive Search Firm: A person to work in a lab in which they will be responsible for developing and optimizing various assays for high throughput screening (HTS). The qualified individual will have experience developing biochemical assays including cell-based assays, homogeneous fluorescence assays, enzymatic assays and binding assays. This person should be familiar with state-of-the-art instrumentation for HTS and knowledge in HTS data analysis. Good communication and organizational skills are a plus. The candidate should possess a B.S., M.S. degree in Biology, Biochemistry, and Molecular Biology or related discipline. Our client is a leading pharmaceutical company with research facilities in New Jersey and can provide excellent benefits (health insurance, dental, and vision plan, paid vacation and more). A high impact, high profile position with excellent opportunity for advancement. Geographic Location of Position: New Jersey USA. Contact: Stan Stavos DMC, Voice: 609-584-8733 Ext. 218, Fax: 609-584-9575 Email: 915608@candseek.com
CPBD, Inc. a biopharmaceutical company focused on innovative drug discovery and development has several key openings in their analytical and computational groups. Analytical Chemist: with a strong background in LC/MS background are encouraged to apply. Experience with NMR, FTIR, statistical analysis, and experience in bioanalytical chemistry and/or medicinal chemistry. Ph.D. required and postdoctoral experience preferred. Work with previous biological samples is essential, as well. Computational chemist: a key position in CPBD Inc.¼s drug discovery group is available for someone with experience in statistical analysis/chemometrics for this multi-disciplinary position. Candidates should have some experience in organic chemistry and understand modern analytical instrumentation. Programming skills desired. Located in Cambridge, MA, CPBD Inc. is a rapidly growing biopharmaceutical company. CPBD offers a comprehensive benefits program, a competitive salary, and an exciting work environment in Boston. Send resume to: Jeffrey A. Ruell, Ph.D., CPBD, Inc. 300 Putnam Avenue, Cambridge, MA 02139. Email: jruell@cpbd.com fax is (617) 868-2538.
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