Chemformation


The Weekly Newsletter of the MIT Chemistry Department

Volume 15, Number 13

Friday, April 16, 1999


Chemformation is published by the Office of the Department Chairman. Please convey items of interest (or mailing list changes) to Linda Earle, Room 18-390, Department of Chemistry, MIT, Cambridge, MA 02139, 617/253-4080; 617/258-7500 (fax) or e-mail to lkn@mit.edu. Back issues of Chemformation can be accessed via the Chemistry Department Website.

Visit the Chemistry Department Website at http://web.mit.edu/chemistry/www/


Seminar Calendar

Thursday, April 22, 1999
5:00 p.m. in MB23
Harvard MIT Physical Chemistry
Seminar at Harvard
Refreshments @ 4:30 p.m. in MB23
Professor Robert J. Silbey
Mass. Institute of Technology
"Spectroscopy in Low Temperature Solids:
Photon Echos, Hole-Burning and
Single Molecule Spectroscopy"
Tuesday, April 27, 1999
9:30 a.m. in Room 6-120
Chemistry 5.561
Chemistry in Industry Lecture Series
Dr. Robert A. Volkmann
Pfizer Central Research
"Discovery of an Amino Acid Peptide Isomerase¾
Tuesday, April 27, 1999
4:00 p.m. in Room 2-105
Seminar in Physical Chemistry
Refreshments @ 4:00 p.m. in 6-233
Professor Michael Fayer
Stanford University
"Protein Dynamics: Ultrafast Infrared
Vibrational Echo Experiments"
Wednesday, April 28, 1999
4:00 p.m. in Room 6-120
Seminar in Inorganic Chemistry
Refreshments @ 3:30 p.m.
Ann Jones
Davison Group
"Rhenium and Technetium Coordination
Chemistry: Applications in Radiopharmaceuticals"
Tuesday, May 4, 1999
9:30 a.m. in Room 6-120
Chemistry 5.561
Chemistry in Industry Lecture Series
Dr. Jeffrey H. Epstein-Toney
Merck Research Laboratories
"Merck¼s Armament Against Antibiotic Resistance:
A Chemical Biology Approach"


Mark Your Calendars!

A special symposium in honor of the memory of George B¸chi will take place on Saturday, November 6, 1999. Speakers will include Professor Albert Eschenmoser, ETH, Switzerland and former Ph.D. students of Professor B¸chi: Dr. George M. Milne, President, Pfizer Central Research; Professor John C. Vederas, University of Alberta; Professor James D. White, Oregon State University; and Professor David R. Williams, Indiana University. For information, visit the B¸chi Memorial Symposium web site at: http://web.mit.edu/chemistry/www/buchi/buchiindex.html.


Massachusetts Institute of Technology
Department of Chemistry

Chemistry 5.561
"Chemistry in Industry" Lecture Series


All lectures 9:30 AM in Room 6-120

April 27 Dr. Robert A. Volkmann
Senior Research Fellow
Pfizer Central Research

"Discovery of an Amino Acid Peptide Isomerase"
May 4 Dr. Jeffrey H. Epstein-Toney
Research Fellow in Endocrinology & Chemical Biology
Merck Research Laboratories

"Merck's Armament Against Antibiotic Resistance:
A Chemical Biology Approach "
May 6 Dr. Steven A. King
Project Leader, Department of Process Research
Abbott Laboratories

"Diastereo- and Enantioselective Synthesis of Highly
Substituted Pyrrolidines Leading to Potent Endothelin Antagonists"
May 11 Dr. Kevin Chapman
Senior Director, Medicinal Chemistry
Merck Research Laboratories

"Combinatorial Approaches to the Somatostatin
Family of Receptors"


Undergraduate Research Symposium

Please join us on Saturday, May 1, 1999 for the Poster Session from 12-2 p.m. in room 56-154. The Senior Thesis Presentations will be held from 2-4 p.m., Room 56-114. Refreshments will be provided. Contact Prof. C. Cummins (ccummins@mit.edu) or Gabriella Browne (gbrowne@mit.edu).


Massachusetts Institute of Technology
Department of Chemistry

A SYMPOSIUM ON

RECENT ADVANCES IN
ORGANIC SYTHESIS

Friday, May 7, 1999
2:00 PM Room 6-120

Marc L. Snapper
Boston College
"New Strategies for the Synthesis
of Biological Probe Reagents"
Rick L. Danheiser
Massachusetts Institute of Technology
"Studies Directed Toward the
Total Synthesis of Glycinoeclepin A"
Stephen F. Martin
University of Texas, Austin
"Recent Advances in the Synthesis of
Heterocyclic Natural Products"
Sponsored by Organic Syntheses, Inc.
For information, contact Professor Rick Danheiser


Massachusetts Institute of Technology
Department of Chemistry

Graduate Research Symposium in
Organic and Bioorganic Chemistry

Friday, May 14, 1999
1:00 PM Room 66-110

Justin Miller
Kemp Group
"Efforts Towards the Total Synthesis of
CP-263,114, A Highly Oxygenated
Natural Product"
Dana Buske
Masamune Group
"The Boron-Mediated Aldol Reaction of Carboxylic Esters"
Greg Dudley
Danheiser Group
"Synthetic Approaches to Ascochlorin
and Related Compounds"
Ron Castellano
Rebek Group
"Reversibly-Formed Polymeric Capsules Based On Calixarenes"
George Greco
Schrock Group
"Dinitrogen Activation by Molybdenum and
Tungsten Complexes That Contain Aryl-
Substituted Triamidoamine Ligands"
* * * * Refreshments * * * *
Kevin Shea
Danheiser Group
"Synthesis and Properties of 9-Alkyl and -Aryl
Cyclopenta[a]phenalene Derivatives"
Marcus Hansen
Buchwald Group
"Recent Progress in Asymmetric Titanium-Catalyzed
Imine Reduction"
JosÈ Rivera-Ortiz
Rebek Group
"Chiral Spaces: Dissymmetric Capsules
Through Self-Assembly"
Dave Simone
Swager Group
"Synthesis, Binding Properties, and Electrochemical Studies
of Crown Ethers, [2]-Catenanes, and [2]-Rotaxanes.
Progress Towards Photoconducting Poly([2]-Catenanes) and Poly([n]-Rotaxanes)"/TD>


Get Organized!

Call Ed Udas at 253-4505 or stop by room 4-065 if students, faculty, or staff need help in organizing their MIT space.


Glass Blowing Services

Bob DiGiacomo will be coming in on Wednesdays or Thursdays to pick up any glass blowing work that you may have available. Please bring any work to room 4-064 or call Ed Udas or John Annese at 3-4505. Bob will do the work on a first-come, first-served basis.


Postdoctoral Positions

The R.W. Johnson Pharmaceutical Research Institute, located in Raritan NJ, conducts pharmaceutical research in therapeutic areas including anti-infectives, central nervous system, dermatology and oncology. Scientist / Sr. Scientist. Become part of our prestigious Drug Discovery Research Organization, published in leading high impact scientific journals. The Growth Factors is a diverse group-seeking scientist with research interests in the area of hematology, oncology or diabetes. Solid expertise in signal transudation pathways, molecular pharmacology and animal model studies is a plus. The ideal applicant will possess a Ph.D. in Molecular Biology, Biochemistry or Pharmacology with 3-5 years' postdoctoral experience. Excellent communication, publication, computer skills, as well as the ability to work in a team environment are essential. Successful candidates will discover new chemical entities, which have an impact onkinases, phosphstses and proteases controlling growth differentiation of cells. Job Code:3159. Postdoctoral Scientist The Growth Factors team currently has a postdoctoral assignment, offering opportunities for publication I the area of hematology, oncology or diabetes. All assignments are 2 years and are renewable dependent upon performance. As a member of the team, you will contribute to the current drug discovery research programs and will assist in identifying new potential targets for assay development and screening Job Code: 3160 Please forward scannable resumes for the above positions, noting the job code to: Margaret Ruvoldt, Johnson & Johnson, JH 123, 501 George Street, New Brunswick, NJ 08901.

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