Chemformation


The Weekly Newsletter of the MIT Chemistry Department

Volume 15, Number 20

Friday, July 2, 1999

Chemformation is published by the Office of the Department Chairman. Please convey items of interest (or mailing list changes) to Linda Earle, Room 18-390, Department of Chemistry, MIT, Cambridge, MA 02139, 617/253-4080; 617/258-7500 (fax) or e-mail to lkn@mit.edu. Back issues of Chemformation can be accessed via the Chemistry Department Website.

Visit the Chemistry Department Website at http://web.mit.edu/chemistry/www/



Welcome New Faculty!!

The faculty, students and staff of the Department of Chemistry welcome our new faculty members: Professor Imperiali and Assistant Professors Cathy Drennan, Tim Jamison and Harald Schwalbe.

Professor Barbara Imperiali joins our organic group arriving from the California Institute of Technology in Pasadena. She received her undergraduate training at University College, London, and her Ph. D. with Professor Satoru Masamune here at MIT. She performed postdoctoral work both at MIT and later with Professor Abeles at Brandeis University before beginning her academic career at Carnegie Mellon. In 1989 she moved to Caltech. Her research is concerned with diverse aspects of protein structure, function, and design. The lab employs a multidisciplinary approach involving synthesis, state-of-the-art spectroscopy, molecular modeling, enzymology, and molecular biology to address fundamental problems at the interface of Chemistry and Biology. Professor Imperiali’s office is located in Room 18-287, her phone is (617) 253-1838, email: imper@mit.edu. Her group members include: Sarah O'Connor and Robert Dempski located in Room18-247; Vincent Tai and Stephano Peluso in 18-230; Dierdre Pearce and Carlos Bosques in 18-244; Michael Shogren-Knaak and Adam Mezo in 18-228; Paula Eason and Maria Ufret in 18-245; Nathalie Jotterand and Kevin McDonnell in 18-226, and Peter Soderman and Jennifer Ottesen in 18-243.

Professor Catherine Drennan is welcomed to the Department in our biological group arriving from the California Institute of Technology where she was a postdoctoral fellow with Professor Douglas Rees. She is a biological chemist, receiving her undergraduate degree from Vassar College and her Ph.D. in biochemistry from the University of Michigan. Cathy's research focuses on problems in structural biology and biological chemistry. Her approach to these problems involves the application of state-of-the-art x-ray crystallography. Professor Drennan's office is in Room16-573A, lab is in Room 56-546 and her phone is 253-5622, email: cdrennan@mit.edu.

Professor Timothy F. Jamison joins the organic group after a distinguished career as a graduate student with Professor Stuart L. Schreiber in the Howard Hughes Medical Institute at Harvard University and as a Damon Runyon-Walter Winchell Cancer Research Fund postdoctoral fellow with Professor Eric N. Jacobson at Harvard University in the Department of Chemistry and Chemical Biology. During the course of his experience at Harvard, his specific accomplishments were in the areas of total synthesis in his graduate career and transition metal-mediated asymmetric catalysis in his postdoctoral program. Professor Jamison's current research interests are focused on the development of new efficient and stereoselective reactions and their use in the synthesis of natural products and related molecules.

Tim was married on June 19th of this year and honeymooned in and around Yellowstone. He and his wife Deborah Hung are the proud uncle and aunt of 1 year old Samantha. Professor Jamison's office number is Room 18-407, and his labs are in 18-546 and 18-565. His phone number is 253-2135 and email is tfj@mit.edu.

Professor Harald Schwalbe will be arriving this fall from Frankfurt, Germany. He is a biological chemist who received his Ph.D. from Frankfurt/M, Germany under Professor Christian Griesinger. He moved to Oxford/UK to hold a Human Capital and Mobility postdoctoral fellowship with Professor Christopher M. Dobson. In 1995, he started his habilitation at the Institute for Organic Chemistry in Frankfurt. Harald's group focuses on the application and development of high resolution NMR spectroscopy to study structure and dynamics of proteins and oligonucleotides and their complexes. In particular, time resolved NMR methodology is being developed to characterize the kinetics of structural transitions or reactions with atomic resolution by NMR spectroscopy. Harald, his wife Caroline and their two sons Malte (age 3) and Jasper (age 1) are looking forward to moving to Boston to explore cultural activities together. Their private interests include making music, singing, playing with the kids, biking and a lot more. Malte already calls for English Good Night Tales.



Thanks To Our Picnic Organizers!

On behalf of the Department Chemistry, a thank you to the following students who made the Department picnic on July 8th a great success!

Dave Amos
Jason Diffendal
Kathy Franz
Mike Hewitt
Brian Hodous
Bob Kennedy
Matt Martin
Kevin Shea
Jaesook Yun



Seminar Calendar

Friday, July 16, 1999
4:00 p.m. in 4-163
Seminar in Organic Chemistry

Professor Sunggak Kim
Korea Advanced Institute of
Science and Technology
"Recent Developments in Free
Radical Acylation Approaches"



Bayer AG to Hold Postdoc Workshop

The Bayer Company is organizing a Post-doc workshop for European Scientists who are currently in the US or in Canada from September 3-5, 1999 in Berkeley, CA. Over the next two years, Bayer will offer several challenging positions in its materials related business units and in Central R&D. They intend to recruit scientists with a particularly strong background in polymer chemistry with a focus on synthesis, characterization and/or processing as well as physicists who are actively involved in materials science. Interested individuals with a background in polymer chemistry or materials science should send their resumes, copies of degrees granted from high school through Ph.D. with record of grades, abstracts of scientific publications and other supporting material to the following address. Dr. Harald Pielartzik, Central R&D, Bayer AG, Rheinuferstrasse 7-9. D-47829, Krefeld, Phone (49) 2151-8857-90 or fax (49) 2152-88-7703 or email: postdoc-materials@bayer-ag.de



Positions

DuPont Pharmaceuticals, Deepwater, NJ: synthesis chemistry positions, seeking M.S./B.S. synthesis chemists who will conduct experiments in synthetic organic chemistry designed to discover and ultimately develop the best process for their drug intermediates and final drug substance. Responsibilities include: designing synthetic pathways to target molecular structures, exploring these approaches in the lab with an objective of reducing to practice, scaling-up to kilo lab/pilot plant, and communicating results to the Chemical Process R&D team. M.S. in organic chemistry or equivalent, or B.S. with research experience or equivalent is required. Fax: (609) 540-4876 or mail their resumes, references and 1-2 page research summary to: DuPont Pharmaceuticals Company, Chemical Process R&D, PRF (S-1), Deepwater, NJ 08023, Att: 126-AN-SM-995. Check their website at: www.dupontpharma.com

Senior Radiopharm Scientist, Montréal: Our client is an internationally recognized Canadian company that develops and markets pharmaceuticals and radiopharmaceuticals for diagnostic and therapeutic applications. This organization is currently seeking an individual to lead the radiopharmaceutical R & D group. This person will be responsible for bringing current projects to completion, identifying new diagnostic and therapeutic candidates, ensuring that all pre-clinical R&D is carried out according to GLP and developing new R&D skills. The selected individual will report directly to the Executive Vice President and will work out of the division headoffice in Montréal. The ideal candidate will have the following profile: Ph.D. in Chemistry, Biochemistry or related area preferably with a focus on peptides R&D experience related to therapeutic drug development within academia or industry Possess a reasonable understanding of the North American regulatory environment. Strong leadership, communication, problem solving and team development skills are essential. Bilingual preferred, but not essential (French/English). A competitive compensation and benefits package is offered with this position. Assistance in obtaining permits to work in Canada will be provided for the successful individual if required. Qualified candidates are invited to submit their resumes in confidence, quoting Reference #99546-A, to: CanMed Consultants Inc., 62 Queen Street South, Mississauga, Ontario, Canada, L5M 1K4, Attention: Dr. Marc Raheja, President, Phone: (905) 567-1080. Fax: (905) 567 1081. E-Mail: mraheja@canmed.com

Holy Cross College, Worcester, MA: Seeks a laboratory supervisor in the Physical and Analytical laboratories with a minimum B.S. degree. Responsible for laboratory preparation and routine maintenance of equipment. Send academic transcripts and resume with three references to: Employment Coordinator, Personnel, College of the Holy Cross, 1 College Street, Worcester, MA 01610-2395.

The Pennsylvania State University: Dept. of Chemistry seeks Executive Officer. Requires a Ph.D. in chemistry or related field, (welcome Ph.D. level candidates who have a strong scientific background coupled to an active interest in scientific administration) together with significant administrative experience and familiarity with the physical support needs for chemical research and education. Outstanding interpersonal, verbal, and written communications; skills; expertise with budgeting, planning and financial management, sound ability to manage human resources and commitment to promoting excellence. Apply to search committee, Chemistry Department, Box E, 152 Davey Lab, University Park, PA 16802. Send cv, and a brief statement of administrative interests/philosophy.



Postdoctoral Positions

Three postdoctoral positions coming available immediately in Theoretical and Computational Studies of Reaction Dynamics in Condensed Phases (primarily in supercritical fluids). I would appreciated if you could bring the announcement, found at http://www-chem.ucdavis.edu/people/tucker.html to the attention of any qualified and interested candidates. Susan C. Tucker, Associate Professor, Department of Chemistry, University of California, Davis, CA 95616, phone: 530-752-2203, fax: 530-752-8995. email: sctucker@ucdavis.edu

University College, London: Applications are invited for a postdoctoral position in the Department of Chemistry in Dr. David Rowley's research group. The project, sponsored by the U.K. Natural Environment Research Council, involves the laboratory study of kinetics and mechanisms of gas phase peroxy radical reactions. These studies will be carried out in collaboration with theoretical studies of peroxy radical reactions led by Professor David Clary, and atmospheric modelling studies incorporating the laboratory data are planned. Interested candidates should contact Dr. David Rowley for further details before applying. The position is initially for 1 year, expected to commence in autumn 1999. Further details of current research interests may be found at

http://web.bham.ac.uk/i.r.sims/irsims/sims_res03.html
http://web.bham.ac.uk/i.r.sims/irsims/sims_res04.html

Details of the Astrophysical Chemistry TMR Network should also be consulted: http://www.bham.ac.uk/Astrochemistry/

Informal enquiries can be made to: Dr Ian R Sims, School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, B15 2TT UK, Tel: +44 121 414 3782, Fax: +44 121 414 4426 Email: i.r.sims@bham.ac.uk

Post-doctoral Research Position in Laser Desorption Time-of-Flight Mass Spectrometry: A position is available immediately for development of a new mass spectrometric approach to biopolymer analysis based on rapid evaporative cooling . Potential applications include high-speed gene sequencing and analysis of protein DNA interactions. The successful applicant will have experience with molecular beams, mass spectrometry and/or lasers. Experience in custom instrument design and construction is particularly desirable. This position is an excellent opportunity for an-oriented physical chemist to branch out into problems ofbiological interest. This is also an opportunity to learn wet-biochemical methodology (e.g. recombinant DNA techniques). Initial appointment will be for one year with a strong likelihood of extension for a second year. Interested applicants should send one CV with three references to: Professors Alec Wodtke and Norbert Reich, Department of Chemistry UCSB, Santa Barbara CA 93106. Wodtke@chem.ucsb.edu, Reich@chem.ucsb.edu

Hanscom Air Force Base: A National Research Council Associate position is available in the COCHISE (COld CHemical Simulation Experiment) facility at the Air Force Research Laboratory at Hanscom Air Force Base, near Boston, Massachusetts. The specific research area will involve the spectroscopy and kinetics of fast nitrogen atom collisions with oxygen molecules [fast N + O2 --> NO(v, high J) + O] where both the precursors and the details of the very highly rotationally excited states of NO will be investigated. Please contact Steven Miller, phone (781) 377-2807 or email miller@plh.af.mil for further information. U.S. citizenship is required for the above positions.

Weizmann Institute: A position is available in the research group of David Tannor at the Weizmann Institute, with a flexible starting date. Applicants should be have a strong background in theoretical chemistry or physics and numerical computations. Research possibilities include theoretical studies of 1) Quantum and semiclassical studies of chemical reaction dynamics, 2) Phase space approach to quantum condensed phase dynamics, 3) Laser control and laser cooling of molecules, 196 (1993); J. Chem. Phys. 106, 1435 (1997); Faraday Disc. (1999, submitted) 4) Dynamics of multielectron atoms. The initial contract will be one year, renewable for a second year. Interested applicants should send a letter of interest outlining relevant experience, a brief CV and the names of three references to David Tannor at the address below. More information, preprints and links are available at http://chemphys.weizmann.ac.il/~tannorProf. David J. Tannor, Department of Chemical Physics, Weizmann Institute, Rehovot, Israel, Phone:+972-8-934-2094, Fax:+972-9-934-4123

The Northwestern University Institute for Environmental Catalysis (IEC) is a new, interdisciplinary research center whose objective is to advance the understanding and application of catalysis for reducing the impact of human activities on the environment. Professor Peter C. Stair, Director of IEC, seeks to hire a postdoctoral associate for a project titled "Surface Science of Catalytic Oxidation". The goal of the project is to elucidate the individual reaction steps in the oxidation of small alkyl groups (methyl and ethyl) on iron oxide, molybdenum oxide, and vanadium oxide surfaces. The postdoctoral associate will also participate in the IEC Industrial Mentor Program with Dow Chemical Company. Further Information on the IEC can be found on the Web at http://easel.cqe.nwu.edu/iec/. Peter C. Stair, Director, Center for Catalysis and Surface Science and Institute for Environmental Catalysis, Professor of Chemistry, Northwestern University, Evanston, IL 60208-3113, Telephone (847) 491-5266, FAX (847) 467-1018

Ben-Gurion University of the Negev: Applications are invited for an open postdoctoral position in the research group of Professor S. Rosenwaks and Dr. I. Bar. Our group is currently engaged in experimental work on exploration of ground and excited state intramolecular dynamics utilizing vibrationally and rovibrationally mediated photodissociation in molecules which may reach selectivity and are of relevance to atmospheric chemistry:

http://www.bgu.ac.il/phys/people/homepages/zamik_rosenwaks.html

Applicants are asked to send their Curriculum Vitae and also arrange to have two or more letters of recommendation sent to Professor S. Rosenwaks, either via email
(zamik@bgumail.bgu.ac.il) or by regular mail to the following address: Professor S. Rosenwaks, Department of Physics, Ben-Gurion University of the Negev, P.O.Box 653, Beer-Sheva 84105 Israel, Fax: ++972-7-647-7745, Tel: ++972-7-6472-421/2/3/4

Johns Hopkins University: A postdoctoral position in inorganic/bioinorganic chemistry is currently available in the Goldberg group in the department of chemistry at Johns Hopkins University, Baltimore, MD. Our research interests involve the synthesis of novel ligands and transition metal complexes as models of metalloprotein active sites, as well as the design and synthetic modification of metalloproteins such as myoglobin in order to control the reactivity at the metal center. Further information can be obtained from our website: www.jhu.edu/~chem/goldbe/index.html. Motivated individuals with broad interests in inorganic/bio-inorganic chemistry are encouraged to apply. Individuals interested in the position should send a curriculum vitae and the names of three references with phone numbers and email addresses to: Dr. David Goldberg, Johns Hopkins University, Department of Chemistry, 3400 N. Charles Street, Baltimore, MD 21218.



Faculty Positions

Please note, unless otherwise specified, most faculty positions require a resume, short description of research plans and to arrange for three letters of recommendation to be sent directly to the specific university or college.

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