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Salvatore Mascia

Contact Info

Office: Bldg. E19-528
Phone: 617-253-6675
Fax: 617-253-2272
Email: smascia@mit.edu

Education:

Mpharm Pharmacy, University of Perugia, 2002; Ph.D. Chemical Engineering, University of Cambridge, 2008

Thesis Title:

Rheology and Processing of Pharmaceutical Pastes

Research Description:

My main research interest lies in the development of new formulations and processes for the production of pharmaceutical dosage forms. Here at MIT I am involved in the Novartis-MIT Center for Continuous Manufacturing, where I am responsible for the drug product development. Currently, I am evaluating the application of extrusion technologies for the continuous manufacture of tablets.

Publications

Mascia, S. and Wilson, D. I. (2008). Biaxial extensional rheology of granular suspensions: the HBP (Herschel-Bulkley for Pastes) model. Journal of Rheology 52 Issue 4, 981-998.

Mascia, S. and Wilson, D. I. (2007). Rheology of concentrated granular suspensions undergoing squeeze flow. Journal of Rheology 51 Issue 3, 493-515.

Mascia, S., Patel, M. J., Rough, S. L., Martin, P.J. and Wilson, D. I. (2006). Liquid phase migration in the extrusion and squeezing of microcrystalline cellulose pastes. European Journal of Pharmaceutical Sciences, 29, 22-34.

Carter, Roy E. ; Newton, J.M. ; Caminho, Ana M. ; Mascia, S. (2004) A novel system for the controlled release of drugs. Pharmaceutical Technology Europe. December issue.