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The Degen Lab

Nanoscale magnetic resonance imaging and spectroscopy
Spin physics and Nanomechanics

 
Nano-MRI title image
Cross-section of Dr. Degen's head recorded in a clinical MRI apparatus Cross-section of two virus particles on top of a molecular surface layer
at 1,000,000x magnified scale recorded in an MRFM apparatus

Welcome to the Degen group at the MIT Department of Chemistry

Research: At the Degen lab we invent, build and operate tools for detecting weak magnetic signals at very small lengthscales. Our goal is to apply these tools for the following purposes:

  • Study of nanoscale spin physics, quantum effects, and other fundamental physical phenomena that become important at these small scales (in condensed matter and quantum physics)
  • Nanoscale MRI imaging of single biological objects 1-100 nm in size (in structural biology)
  • Chemical analysis of heterogeneous surfaces with nanometer resolution using spectroscopy (in surface science)
    Read more...
Techniques: Magnetic signals from spins in nanometer-sized samples are typically extremely small. Our lab currently specializes on two experimental approaches that have the necessary sensitivity to examine these signals. In Magnetic Resonance Force Microscopy (MRFM), we take advantage of ultrasensitive cantilevers such as used in force microscopy to measure spins by their magnetic force. In recently invented Scanning Diamond Magnetometry, we rely on the exquiste magneto-optical properties of the NV defect in diamond to sense the same minute magnetic fields optically and under ambient conditions. Along the way of improving the sensitivity of our instrumentation, we also hope to make exciting new physical discoveries. Read more...
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