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Damon Runyon Fellow Laboratory of Robert S. Langer David H. Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology |
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Publications: |
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Peer-Reviewed: (28) Schroeder, A.; Heller, D. A.; Winslow, M. M.; Dahlman, J. E.; Pratt, G. W.; Langer, R.; Jacks, T.; Anderson, D. G.: Treating metastatic cancer with nanotechnology. Nature Reviews Cancer (2012) 12 39-50. (27) Boghossian, A. A.; Zhang, J.; Barone, P. W.; Reuel, N. F.; Kim, J-H.; Heller, D. A.; Ahn, J-H.; Hilmer, A. J.; Rwei, A. Arkalgud, J. R.; Zhang, C. T.; Strano, M. S.: Near-Infrared Fluorescent Sensors based on Single-Walled Carbon Nanotubes for Life Sciences Applications. ChemSusChem (2011) 4 848-863. (26) Heller, D. A.; Pratt, G. W.; Zhang, J.; Nair, N.; Hansborough, A. J.; Boghossian, A. A.; Reuel, N. F.; Barone, P. W.; Strano, M. S.: Peptide secondary structure modulates single-walled carbon nanotube fluorescence as a chaperone sensor for nitroaromatics. Proceedings of the National Academy of Sciences (2011) 108, 8544-8549. (25) Zhang, J.; Boghossian, A. A.; Barone, P.
W.; Rwei, A.; , Kim, J-H.; Lin, D.; Heller, D. A.; Hilmer,
A. J.; Nair, N.; Reuel, N. F.; Strano, M. S.: Single Molecule Detection of Nitric Oxide
Enabled by d(AT)15 DNA Adsorbed to Near Infrared Fluorescent
Single-Walled Carbon Nanotubes. Journal of the American Chemical Society (2010) 133, 567-581. (24) Han, J-H.; Paulus, G. L. C.; Maruyama, R.; Heller, D. A.; Kim, W-J.; Barone, P. W.; Lee, C. Y.; Choi, J. H. Ham, M-H.; Song,
C.; Fantini, C.; Strano, M. S.: Exciton
antennas and concentrators from core–shell and corrugated carbon nanotube
filaments of homogeneous composition. Nature Materials (2010) 9, 833-839. (23) Ham, M-H.; Choi, J. H.; Boghossian, A. A.; Jeng, E. S.; Graff, R. A.; Heller, D. A.; Chang, A. C.; Mattis, A.; Bayburt, T. H.; Grinkova, Y. V.; Zeiger, A. S.; Van Vliet, K. J.; Hobbie, E. K.; Sligar, S. G.; Wraight, C. A.; Strano, M. S.: Photoelectrochemical complexes for solar energy conversion that chemically and autonomously regenerate. Nature Chemistry (2010) 2, 929-936. (22) Jin, H.; Heller, D. A.; Kalbacova, M.; Kim, J-H.; Zhang, J,; Boghossian, A. A.; Maheshri, N.; Strano, M. S.; Detection of single-molecule H2O2 signalling from epidermal growth factor receptor using fluorescent single-walled carbon nanotubes. Nature Nanotechnology (2010) 5, 302-309. (21) Kim, J-H.; Ahn,
J-H.; Barone, P. W.; Jin, H.; Zhang, J.; Heller, D. A.; Strano, M. S.; A Luciferase/Single-Walled Carbon
Nanotube Conjugate for Near-Infrared Fluorescent Detection of Cellular ATP. Angewandte Chemie (2010) 46, 1456-1459. (20) Kim, J-H.; Heller, D. A.; Jin, H.; Barone, P. W.;
Song, C.; Zhang, J.; Trudel, L. J.; Wogan, G. N.; Tannenbaum, S.
R.; Strano, M.S.; The rational
design of nitric oxide selectivity in single-walled carbon nanotube
near-infrared fluorescence sensors for biological detection. Nature
Chemistry (2009) 1, 473-481. (19) Heller, D. A.; Jin, H.; Martinez, B. M.; Patel, D.; Miller, B. M.; Yeung, T-K.; Jena, P. V.; Höbartner, C.; Ha, T.; Silverman, S. K.; Strano, M. S.; Multi-Modal Optical Sensing and Analyte Specificity Via Single-Walled Carbon Nanotubes. Nature Nanotechnology (2009) 4, 114-120. (18) Jin, H.; Heller, D. A.; Sharma, R.; Strano, M. S.; Size-Dependent Cellular Uptake and Expulsion of Single-Walled Carbon Nanotubes: Single Particle Tracking and a Generic Uptake Model for Nanoparticles. ACS Nano (2009) 3, 149-158. (17) Jin, H.; Heller, D. A.; Kim, J-H.; Strano, M. S.; A Stochastic Analysis of Stepwise Fluorescence Quenching Reactions on Single-Walled Carbon Nanotubes. Nano Letters (2008) 8, 4299-4304. (16) Jin, H.; Heller, D. A.; Strano, M. S.; Single-Particle
Tracking of Endocytosis and Exocytosis of Single-Walled Carbon Nanotubes in
NIH-3T3 Cells. Nano Letters
(2008) 8, 1577-1585. (15)
Rajan, A.; Strano, M. S.; Heller,
D. A.; Hertel, T.; Schulten, K. Length-Dependent Optical Effects in
Single Walled Carbon Nanotubes. Journal of Physical Chemistry B (2008) 112, 6211-6213. (14) Jin, H.; Jeng, E. S.; Heller, D. A.; Jena, P. V.; Kirmse, R.; Langowski, J.; Strano, M. S. Divalent Ion and Thermally Induced DNA Conformational Polymorphism on Single-walled Carbon Nanotubes. Macromolecules (2007) 40, 6731 – 6739. (13) Choi, J. H.; Nguyen, F. T.; Barone, P. W.; Heller, D. A.;
Moll, A. E.; Patel, D.; Boppart, S. A.; Strano, M.
S. Multimodal Biomedical Imaging with
Asymmetric Single-walled Carbon Nanotube/Iron Oxide Nanoparticle Complexes.
Nano Letters (2007) 7, 861-867. (12) Heller, D. A.; Jeng, E. S.; Yeung,
T.-K.; Martinez, B. M.; Moll, A. E.; Gastala, J. B.; Strano, M. S. Optical Detection of DNA Conformational Polymorphism
on Single-Walled Carbon Nanotubes. Science (2006) 311, 508-511. (11) Jorio, A.; Fantini, C.;
Pimenta, M. A.; Heller, D. A.;
Strano, M. S.; Dresselhaus, M. S.; Oyama, Y.; Jiang, J.; Saito, R. Carbon Nanotube Population Analysis from Raman
and Photoluminescence Intensities. Applied Physics Letters (2006) 88,
023109 (10) Heller, D. A.; Baik, S.; Eurell, T. E.;
Strano, M. S. Single-Walled Carbon Nanotube
Spectroscopy in Live Cells: Towards Long-Term Labels and Optical Sensors. Advanced Materials
(2005) 17, 2793-2799. (9) Graff,
R. A.; Swanson, J. P.; Barone, P. W.; Baik, S.; Heller, D. A.; Strano, M. S. Achieving Individual-Nanotube
Dispersion at High-Loading in Single-Walled Carbon Nanotube Composites. Advanced Materials
(2005) 17, 980-984. (8) Lewis, E. K.; Haaland,
W. C.; Nguyen, F.; Heller, D. A.;
Allen, M. J.; MacGregor, R. R.; Berger, C. S.;
Willingham, B.; Burns, L. A.; Scott, G. B. I.; Kittrell,
C.; Johnson, B. R.; Curl, R. F.; Metzker, M. L. Color-blind fluorescence detection
for four-color DNA sequencing. Proceedings of the (7)
Barone, P. W.; Baik, S.; Heller, D. A.; Strano, M. S. Near-infrared optical sensors
based on single-walled carbon nanotubes. Nature Materials (2005), 4, 86-92. (6) Heller, D. A.; Barone,
P. W.; Strano, M. S. Sonication-induced
changes in chiral distribution: A complication in the use of single-walled
carbon nanotube fluorescence for determining species distribution. Carbon (2005) 43, 651-653. (5) Heller, D. A.; Garga,
V.; Kelleher, K. J.; Lee, T-C.; Mahbubani, S.; Sigworth, L. A.; Lee, T. R.; Rea, M. A. Patterned networks of mouse hippocampal neurons on peptide-coated gold
surfaces. Biomaterials (2005) 26, 883-889. (4) Heller, D. A.; Mayrhofer,
R. M.; Baik, S.; Grinkova,
Y. V.; Usrey, M. L.; Strano, M. S. Concomitant
Length and Diameter Separation of Single-Walled Carbon Nanotubes. Journal
of the American Chemical Society (2004) 126, 14567-14573. (3) Heller, D. A.; Barone,
P. W.; Swanson, J. P.; Mayrhofer, R. M.; Strano, M.
S. Using Raman Spectroscopy to Elucidate the
Aggregation State of Single-Walled Carbon Nanotubes. Journal of Physical Chemistry B
(2004) 108, 6905-6909. (2) Strano, M. S.; Zheng, M.; Jagota, A.; Onoa, G. B.; Heller,
D. A.; Barone, P. W.; Usrey,
M. L. Understanding the nature of the
DNA-assisted separation of single-walled carbon nanotubes using fluorescence
and Raman spectroscopy. Nano Letters (2004) 4, 543-550. (1) Doorn,
S. K.; Heller, D. A.; Barone, P. W.; Usrey, M. L.;
Strano, M. S. Resonant Raman excitation profiles of
individually dispersed single walled carbon nanotubes in solution. Applied
Physics A: Materials Science & Processing (2004) 8, 1147-1155. Book Chapters
and Other Publications: Strano, M. S.; Boghossian,
A. A.; Kim, W-J.; Barone, P. W.; Jeng, E. S.; Heller, D. A.; Nair, N.; Jin, H.;
Sharma, R.; Lee. C. Y.; The
Chemistry of Single-Walled Nanotubes.
MRS Bulletin 34 (2009) 950-961. Barone, P. W.; Jeng, E. S.; Heller, D. A.; Strano, M. S.; “Biosensors based on single-walled carbon
nanotube fluorescence.” in Handbook of Biosensors and Biochips ( Doorn, S. K.; Heller, D. A.; Usrey, M. L.; Barone, P. W.; Strano, M. S.; “Raman Spectroscopy of
Single-Walled Carbon Nanotubes: Probing Electronic and Chemical Behavior.” in
Carbon Nanotubes: Properties and
Applications ( Strano, M. S.; Usrey, M. L.; Barone, P. W.; Heller, D. A.; Baik,
S. "The Selective Chemistry of Single Walled Carbon Nanotubes." in Applied
Physics of Carbon Nanotubes (Berlin: Springer-Verlag,
2005.) |
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Teaching
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MIT
Video – Sensors in Cells Podcast - Museum
of Science, Boston: Biosensors |
Press: Carbon nanotube and bee venom explosive/pesticide sensor, Carbon nanotube sensor for genotoxins. |
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Article:
Heller, D. A. Teacher
for a Day. Science Scope (2003) |
CNST
Student Initiative, University of Illinois |
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Robert S.
Langer Research Group (Current Group) Michael
S. Strano Research Group (Graduate) |
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