Daniel A. Heller

 

Damon Runyon Fellow

Laboratory of Robert S. Langer

David H. Koch Institute for Integrative Cancer Research

Massachusetts Institute of Technology

 

 

 

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Publications:

 

 

Peer-Reviewed:

 

(28)  Schroeder, A.; Heller, D. A.; Winslow, M. M.; Dahlman, J. E.; Pratt, G. W.; Langer, R.; Jacks, T.; Anderson, D. G.: Treating metastatic cancer with nanotechnology. Nature Reviews Cancer (2012) 12 39-50.

 

(27)  Boghossian, A. A.; Zhang, J.; Barone, P. W.; Reuel, N. F.; Kim, J-H.; Heller, D. A.; Ahn, J-H.; Hilmer, A. J.; Rwei, A. Arkalgud, J. R.; Zhang, C. T.; Strano, M. S.: Near-Infrared Fluorescent Sensors based on Single-Walled Carbon Nanotubes for Life Sciences Applications. ChemSusChem (2011) 4 848-863.

 

(26)  Heller, D. A.; Pratt, G. W.; Zhang, J.; Nair, N.; Hansborough, A. J.; Boghossian, A. A.; Reuel, N. F.; Barone, P. W.; Strano, M. S.: Peptide secondary structure modulates single-walled carbon nanotube fluorescence as a chaperone sensor for nitroaromatics. Proceedings of the National Academy of Sciences (2011) 108, 8544-8549.

 

(25)  Zhang, J.; Boghossian, A. A.; Barone, P. W.; Rwei, A.; , Kim, J-H.; Lin, D.; Heller, D. A.; Hilmer, A. J.; Nair, N.; Reuel, N. F.; Strano, M. S.: Single Molecule Detection of Nitric Oxide Enabled by d(AT)15 DNA Adsorbed to Near Infrared Fluorescent Single-Walled Carbon Nanotubes. Journal of the American Chemical Society (2010) 133, 567-581.

 

(24)   Han, J-H.; Paulus, G. L. C.; Maruyama, R.; Heller, D. A.; Kim, W-J.; Barone, P. W.; Lee, C. Y.; Choi, J. H. Ham, M-H.; Song, C.; Fantini, C.; Strano, M. S.:  Exciton antennas and concentrators from core–shell and corrugated carbon nanotube filaments of homogeneous composition.  Nature Materials (2010) 9, 833-839.

 

(23)   Ham, M-H.; Choi, J. H.; Boghossian, A. A.; Jeng, E. S.; Graff, R. A.; Heller, D. A.; Chang, A. C.; Mattis, A.; Bayburt, T. H.; Grinkova, Y. V.; Zeiger, A. S.; Van Vliet, K. J.; Hobbie, E. K.; Sligar, S. G.; Wraight, C. A.; Strano, M. S.: Photoelectrochemical complexes for solar energy conversion that chemically and autonomously regenerate. Nature Chemistry (2010) 2, 929-936.

 

(22)   Jin, H.; Heller, D. A.; Kalbacova, M.; Kim, J-H.; Zhang, J,; Boghossian, A. A.; Maheshri, N.; Strano, M. S.; Detection of single-molecule H2O2 signalling from epidermal growth factor receptor using fluorescent single-walled carbon nanotubes.  Nature Nanotechnology (2010) 5, 302-309.

 

(21)   Kim, J-H.; Ahn, J-H.; Barone, P. W.; Jin, H.; Zhang, J.; Heller, D. A.; Strano, M. S.; A Luciferase/Single-Walled Carbon Nanotube Conjugate for Near-Infrared Fluorescent Detection of Cellular ATP.  Angewandte Chemie (2010) 46, 1456-1459.

 

(20)   Kim, J-H.; Heller, D. A.; Jin, H.; Barone, P. W.; Song, C.; Zhang, J.; Trudel, L. J.; Wogan, G. N.; Tannenbaum, S. R.; Strano, M.S.; The rational design of nitric oxide selectivity in single-walled carbon nanotube near-infrared fluorescence sensors for biological detection. Nature Chemistry (2009) 1, 473-481.

 

(19)   Heller, D. A.; Jin, H.; Martinez, B. M.; Patel, D.; Miller, B. M.; Yeung, T-K.; Jena, P. V.; Höbartner, C.; Ha, T.; Silverman, S. K.; Strano, M. S.; Multi-Modal Optical Sensing and Analyte Specificity Via Single-Walled Carbon Nanotubes. Nature Nanotechnology (2009) 4, 114-120.

 

(18)   Jin, H.; Heller, D. A.; Sharma, R.; Strano, M. S.; Size-Dependent Cellular Uptake and Expulsion of Single-Walled Carbon Nanotubes: Single Particle Tracking and a Generic Uptake Model for Nanoparticles. ACS Nano (2009) 3, 149-158.

 

(17)   Jin, H.; Heller, D. A.; Kim, J-H.; Strano, M. S.; A Stochastic Analysis of Stepwise Fluorescence Quenching Reactions on Single-Walled Carbon Nanotubes. Nano Letters (2008) 8, 4299-4304.

 

(16)   Jin, H.; Heller, D. A.; Strano, M. S.; Single-Particle Tracking of Endocytosis and Exocytosis of Single-Walled Carbon Nanotubes in NIH-3T3 Cells. Nano Letters (2008) 8, 1577-1585.

 

(15)   Rajan, A.; Strano, M. S.; Heller, D. A.; Hertel, T.; Schulten, K. Length-Dependent Optical Effects in Single Walled Carbon Nanotubes. Journal of Physical Chemistry B  (2008) 112, 6211-6213.

 

(14)   Jin, H.; Jeng, E. S.; Heller, D. A.; Jena, P. V.; Kirmse, R.; Langowski, J.; Strano, M. S.  Divalent Ion and Thermally Induced DNA Conformational Polymorphism on Single-walled Carbon Nanotubes. Macromolecules (2007) 40, 6731 – 6739.

 

(13)   Choi, J. H.; Nguyen, F. T.; Barone, P. W.; Heller, D. A.; Moll, A. E.; Patel, D.; Boppart, S. A.; Strano, M. S. Multimodal Biomedical Imaging with Asymmetric Single-walled Carbon Nanotube/Iron Oxide Nanoparticle Complexes. Nano Letters (2007) 7, 861-867.

 

(12)   Heller, D. A.; Jeng, E. S.; Yeung, T.-K.; Martinez, B. M.; Moll, A. E.; Gastala, J. B.; Strano, M. S. Optical Detection of DNA Conformational Polymorphism on Single-Walled Carbon Nanotubes. Science (2006) 311, 508-511.

 

(11)   Jorio, A.; Fantini, C.; Pimenta, M. A.; Heller, D. A.; Strano, M. S.; Dresselhaus, M. S.; Oyama, Y.; Jiang, J.; Saito, R. Carbon Nanotube Population Analysis from Raman and Photoluminescence Intensities. Applied Physics Letters (2006) 88, 023109

 

(10)   Heller, D. A.; Baik, S.; Eurell, T. E.; Strano, M. S. Single-Walled Carbon Nanotube Spectroscopy in Live Cells: Towards Long-Term Labels and Optical Sensors. Advanced Materials (2005) 17, 2793-2799.

 

(9)   Graff, R. A.; Swanson, J. P.; Barone, P. W.; Baik, S.; Heller, D. A.; Strano, M. S. Achieving Individual-Nanotube Dispersion at High-Loading in Single-Walled Carbon Nanotube Composites. Advanced Materials (2005) 17, 980-984.

 

(8)   Lewis, E. K.; Haaland, W. C.; Nguyen, F.; Heller, D. A.; Allen, M. J.; MacGregor, R. R.; Berger, C. S.; Willingham, B.; Burns, L. A.; Scott, G. B. I.; Kittrell, C.; Johnson, B. R.; Curl, R. F.; Metzker, M. L. Color-blind fluorescence detection for four-color DNA sequencing. Proceedings of the National Academy of Sciences (2005) 102, 5346-5351.

 

(7)   Barone, P. W.; Baik, S.; Heller, D. A.; Strano, M. S. Near-infrared optical sensors based on single-walled carbon nanotubes. Nature Materials (2005), 4, 86-92.

 

(6)   Heller, D. A.; Barone, P. W.; Strano, M. S. Sonication-induced changes in chiral distribution: A complication in the use of single-walled carbon nanotube fluorescence for determining species distribution. Carbon (2005) 43, 651-653.

 

(5)   Heller, D. A.; Garga, V.; Kelleher, K. J.; Lee, T-C.; Mahbubani, S.; Sigworth, L. A.; Lee, T. R.; Rea, M. A. Patterned networks of mouse hippocampal neurons on peptide-coated gold surfaces. Biomaterials (2005) 26, 883-889.

 

(4)   Heller, D. A.; Mayrhofer, R. M.; Baik, S.; Grinkova, Y. V.; Usrey, M. L.; Strano, M. S. Concomitant Length and Diameter Separation of Single-Walled Carbon Nanotubes. Journal of the American Chemical Society (2004) 126, 14567-14573.

 

(3)   Heller, D. A.; Barone, P. W.; Swanson, J. P.; Mayrhofer, R. M.; Strano, M. S. Using Raman Spectroscopy to Elucidate the Aggregation State of Single-Walled Carbon Nanotubes. Journal of Physical Chemistry B (2004) 108, 6905-6909.

 

(2)   Strano, M. S.; Zheng, M.; Jagota, A.; Onoa, G. B.; Heller, D. A.; Barone, P. W.; Usrey, M. L. Understanding the nature of the DNA-assisted separation of single-walled carbon nanotubes using fluorescence and Raman spectroscopy. Nano Letters (2004) 4, 543-550.

 

(1)   Doorn, S. K.; Heller, D. A.; Barone, P. W.; Usrey, M. L.; Strano, M. S. Resonant Raman excitation profiles of individually dispersed single walled carbon nanotubes in solution. Applied Physics A: Materials Science & Processing (2004) 8, 1147-1155.

 

Book Chapters and Other Publications:

Strano, M. S.; Boghossian, A. A.; Kim, W-J.; Barone, P. W.; Jeng, E. S.; Heller, D. A.; Nair, N.; Jin, H.; Sharma, R.; Lee. C. Y.; The Chemistry of Single-Walled Nanotubes.  MRS Bulletin 34 (2009) 950-961.

 

Barone, P. W.; Jeng, E. S.; Heller, D. A.; Strano, M. S.; “Biosensors based on single-walled carbon nanotube fluorescence.” in Handbook of Biosensors and Biochips (Chichester: John Wiley & Sons, 2007.)

 

Doorn, S. K.; Heller, D. A.; Usrey, M. L.; Barone, P. W.; Strano, M. S.; “Raman Spectroscopy of Single-Walled Carbon Nanotubes: Probing Electronic and Chemical Behavior.” in Carbon Nanotubes: Properties and Applications (Boca Raton: Taylor & Francis Group, 2006.)

 

Strano, M. S.; Usrey, M. L.; Barone, P. W.; Heller, D. A.; Baik, S. "The Selective Chemistry of Single Walled Carbon Nanotubes." in Applied Physics of Carbon Nanotubes (Berlin: Springer-Verlag, 2005.)

 

Teaching and Outreach:

Links:

MIT Video – Sensors in Cells

Podcast - Museum of Science, Boston: Biosensors

Podcast - Museum of Science, Boston: Explosives Sensors

Wizardry Outreach

Curriculum Vitae

 

Press: Carbon nanotube and bee venom explosive/pesticide sensor, Carbon nanotube sensor for genotoxins.

Article: Heller, D. A. Teacher for a Day. Science Scope (2003)

CNST Student Initiative, University of Illinois

Chem 233 Analytical Chemistry Merit Workshop, Fall 2003    

Robert S. Langer Research Group (Current Group)

Michael S. Strano Research Group (Graduate)