 |
| This
activity is
appropriate for children ages 12 and up. Some previous study of
cells, DNA, chromosomes and genes is preferable. |
| The "Shape of Life" begins with an
exploration of the structural
components of chromosomes, including a discussion of genes and traits.
The LEGO® fish is introduced as a model to demonstrate how genes can be
expressed in a "living" creature. Our fish has only three
chromosome pairs, rather than a human's 23 pairs, to facilitate an
easier understanding of the relationship between gene and trait.
Students learn how DNA's sequence gets replicated through mitosis in
somatic cells. Chromosomes, cell membranes and spindle fibers are
modelled by LEGO® bricks as the students move
through the stages of interphase, prophase, metaphase, anaphase and
telophase. |
 |
 |
In the second half of this
activity, students use LEGO® DNA
kits, identifying the LEGO® bricks that represent molecules of
sugar,
phosphate, or nucleotide bases. Using these pieces, the students
construct their own model of the DNA ladder, with careful attention to
base pairing. A brief overview of DNA replication follows, using the
LEGO® DNA as a simulation aid. Students then are given individual
exploration time to answer questions and investigate variations of
their DNA model.
|
|
