 |
 |
|
| This activity is appropriate for children ages 12 and up. Some previous study of cells, DNA, chromosomes and genes is preferable. |
| |
"Shape of Life" begins with an exploration of the structural components of chromosomes, including a discussion of genes and traits. The LEGO® fish is introduced as a model to demonstrate how genes can be
expressed in a "living" creature.
Our fish has only three chromosome pairs, rather than a human's 23 pairs, to facilitate an easier understanding of the relationship between gene and trait. Students learn how DNA's sequence gets replicated through mitosis in
somatic cells. Chromosomes, cell membranes and spindle fibers are modelled by LEGO® bricks as the students move
through the stages of interphase, prophase, metaphase, anaphase and telophase. |
 |
| |
 |
|
In the second half of this activity,students use LEGO® DNA kits, identifying the LEGO® bricks that represent molecules of sugar, phosphate, or nucleotide bases. Using these pieces, the students construct their own model of the DNA ladder, with careful attention to base pairing. A brief overview of DNA replication follows, using the LEGO® DNA as a simulation aid. Students then are given individual exploration time to answer questions and investigate variations of their DNA model. | |
| |
|
|
|
|
|
