Home      |      Research      |      People      |      Publications      |      Animations      |      Contact Us
About Us
chemical structure

Major goals of the Engelward laboratory are to contribute to our understanding of factors that impact genomic stability through basic research, and through the development & application of novel technologies.

  • Develop mouse models for fluorescent detection of rare genetic changes
  • Reveal the impact of genes, environment and physiological conditions on genomic stability
  • Create a high throughput platform for measuring DNA damage in human cells
  • Apply high throughput technology for epidemiology and drug development
  • Explore the interfaces among DNA damage, repair and infection
  • Mitigate infection-induced toxicity

Research Areas:

New Technologies: Fluorescence Detection of Genetic Change in vivo
We have genetically engineered two mouse models that enable direct visualization of cells that harbor rare genetic changes in situ. More >>

New Technologies: Microarray for High Throughput DNA Damage Quantification
Using microfabrication techniques, we have developed a novel platform for high throughput analysis of DNA damage in human cells. More >>

Basic Research & Application of In-House Technologies to Reveal Factors that Impact Genomic Stability
Increasing our understanding of the underlying genetic, environmental, and physiological conditions that modulate genomic stability is one of our major goals. More >>