Homologous Recombination

• Two-Ended Double Strand Break Repair via Synthesis Dependent Strand Annealing (SDSA)
• Two-Ended Double Strand Break Repair via Double Strand Break Repair (DSBR)
• Repair of a broken replication fork: One-Ended Double Strand Break Repair
• Two-Ended Double Strand Break Repair via Single Strand Annealing (SSA)

Non-Homologous End-Joining (NHEJ)

• Two-Ended Double Strand Break Repair via NHEJ
• Mis-repair of a broken replication fork: One-Ended Break Mis-joining via NHEJ

All Animations were created by Justin H. Lo.

Animations published in DNA Repair, Copyright © 2007
Helleday T, Lo J, van Gent DC, Engelward BP. DNA double-strand break repair: From mechanistic understanding to cancer treatment. DNA Repair. (14 Mar 2007)