ANIMATIONS
 

 

 

Homologous Recombination

 


Two-Ended Double Strand Break Repair via
Synthesis Dependent Strand Annealing (SDSA)

 

 

 

Two-Ended Double Strand Break Repair via
Double Strand Break Repair (DSBR)

 

Repair of a broken replication fork:

One-Ended Double Strand Break Repair

 

Two-Ended Double Strand Break Repair via
Single Strand Annealing (SSA)

 

Non-Homologous End-Joining (NHEJ)

 

Two-Ended Double Strand Break Repair via NHEJ

 

 

 

 

Mis-repair of a broken replication fork:

One-Ended Break Mis-joining via NHEJ 

 

 

 

 

All Animations were created by Justin H. Lo. 

Animations published in DNA Repair, Copyright © 2007
Helleday T, Lo J, van Gent DC, Engelward BP. DNA double-strand break repair: From mechanistic understanding to cancer treatment. DNA Repair. (14 Mar 2007)

 

 

 

 

 

 

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