2008

Wiktor-Brown DM, Kwon HS, Nam YS, So PT, Engelward BP. Integrated one- and two-photon imaging platform reveals clonal expansion as a major driver of mutation load. Proc Natl Acad Sci U S A. 105 (2008)

Wiktor-Brown DM, Olipitz W, Hendricks CA, Rugo RE, Engelward BP. Tissue specific differences in the accumulation of sequence rearrangements with age. DNA Repair, 7:5 694-703 (2008)

Kim KH, Ragan T, Previte MJR, Bahlmann K, Harley BA, Almeida KH, Stitt MS, Hendricks CA, Wiktor-Brown D, Engelward BP, So PT. Three-dimensional tissue cytometer based on high-speed multiphoton microscopy. Cytometry Part A, 71A:12 991-1002 (2007)
 

Helleday T, Lo J, van Gent DC, Engelward BP. DNA double-strand break repair: From mechanistic understanding to cancer treatment. DNA Repair (Amst), 6: 923 (2007)

Engelward BP, Roberts RJ. Open access to research is in the public interest. PLoS Biol. 5:e48 (2007)

2006

Wiktor-Brown DM, Hendricks CA, Olipitz W, Rogers AB, Engelward BP. Applications of fluorescence for detecting rare sequence rearrangements in vivo. Cell Cycle. 5:2715-9 (2006)

Wiktor-Brown DM, Hendricks CA, Olipitz W, Engelward BP. Age-dependent accumulation of recombinant cells in the mouse pancreas revealed by in situ fluorescence imaging. Proc Natl Acad Sci U S A. 103: 11862-7 (2006).
 

Nowosielska A, Smith SA, Engelward BP, Marinus MG. Homologous recombination prevents methylation-induced toxicity in Escherichia coli. Nucleic Acids Res. 34: 2258-2268 (2006).

Li CQ, Pang B, Kiziltepe T, Trudel LJ, Engelward BP, Dedon PC, Wogan GN.  Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells. Chem Res Toxicol. 19: 399-406 (2006).

Koturbash I, Rugo RE, Hendricks CA, Loree J, Thibault B, Kutanzi K, Pogribny I, Yanch JC, Engelward BP, Kovalchuk O. Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo. Oncogene. (2006)

2005

R. E. Rugo, K. H. Almeida, C. A. Hendricks, V. S. Jonnalagadda, and B. P. Engelward, A single acute exposure to a chemotherapeutic agent induces hyper-recombination in distantly descendant cells and in their neighbors, Oncogene. 24:5016-25 (2005).

V. S. Jonnalagadda, T. Matsuguchi, and B. P. Engelward, Interstrand crosslink-induced homologous recombination carries an increased risk of deletions and insertions, DNA Repair. 4:594-605 (2005).

T. Kiziltepe, A. Yan, M. Dong, V. S. Jonnalagadda, P. C. Dedon, and B. P. Engelward, Delineation of the chemical pathways underlying nitric oxide-induced homologous recombination in mammalian cells, Chem Biol. 12:357-69 (2005).

2004

O. Kovalchuk, C. A. Hendricks, S. Cassie, A. J. Engelward, and B. P. Engelward, In vivo recombination after chronic damage exposure falls to below spontaneous levels in Recombomice. Mol. Cancer Res. 2: 567-573 (2004).

C. A. Hendricks and B. P. Engelward, Recombomice: The past, present, and future of recombination-detection in mice, DNA Repair, 3: 1255-1261 (2004).

2003

C. A. Hendricks, K. H. Almeida, M. S. Stitt, V. S. Jonnalagadda, R. E. Rugo, G. F. Kerrison, and B. P. Engelward, Spontaneous mitotic homologous recombination at an enhanced yellow fluorescent protein (EYFP) cDNA direct repeat in transgenic mice, Proc. Natl. Acad. Sci. USA, 100:6325-6330 (2003).

2002

E. J. Spek, L. N. Vuong, T. Matsuguchi, M. G. Marinus, and B. P. Engelward, Nitric oxide induced homologous recombination in Escherichia coli is promoted by DNA glycosylases, J. Bacteriol., 184:3501-3507 (2002).

C. A. Hendricks, M. Razlog, T. Matsuguchi, A. Goyal, A. L. Brock, and B. P. Engelward, The S. cerevisiae Mag1 3-methyladenine DNA glycosylase modulates susceptibility to homologous recombination, DNA Repair 1:645-659 (2002).

2001

E. J. Spek, T. L. Wright, M. S. Stitt, N. R. Taghizadeh, S. R. Tannenbaum, M. G. Marinus, and B. P. Engelward.  Recombinational Repair is Critical for the Survival of Escherichia coli Exposed to Nitric Oxide, J. Bacteriol., 183:131-138 (2001).

2000

S. Smith and B. P. Engelward. In vivo Repair of Methylation Damage in Aag 3-Methyladenine DNA Glycosylase Null Mouse Cells, Nucleic Acids Res., 28:3294-3300 (2000).

1999

B. J. Glassner, G. Weeda, J. M. Allan, J. L. Broekhof, N. H. Carls, I. Donker, B. P. Engelward, R. J. Hampson, R. Hersmus, M. J. Hickman, R. B. Roth, H. B. Warren, M. M. Wu, J. H. Hoeijmakers, L. D. Samson, DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents, Mutagenesis, 14:339-347 (1999).

1998

B. P. Engelward, J. M. Allan, A. J. Dreslin, J. D. Kelly, M. M. Wu, B. Gold, and L. D. Samson, A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome,  J. Biol. Chem., 273: 5412-5418 (1998).

J. M. Allan, B. P. Engelward, A. J. Dreslin, M. D. Wyatt, M. Tomasz, and L. D. Samson, Mammalian 3-methyladenine DNA glycosylase protects against the toxicity and clastogenicity of certain chemotherapeutic DNA cross-linking agents, Cancer Res., 58: 3965-3973 (1998).

D. M. Wilson, III, B. P. Engelward, and L. Samson. Prokaryotic base excision repair, in J. A. Nickoloff and M. F. Hoekstra (eds.), DNA Damage and Repair: Biochemistry, Genetics, and Cell Biology, Humana Press, Inc., Totowa, NJ, Vol. I, pp. 29-64 (1998).

H. Jacobs, Y. Fukita, G. T. J. van der Horst, J. de Boer, G. Weeda, J. Essers, N. de Wind, B. P. Engelward, L. Samson, S. Verbeek, J. M. de Murcia, G. de Murcia, H. te Riele, and K. Rajewsky. Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice, J. Exp. Medicine, 187: 1735-1743 (1998).

1997

B. P. Engelward, G. Weeda, M.D. Wyatt, J. L. M. Broekhof, J. de Wit, I. Donker, J. M. Allan, B. Gold, J. H. J. Hoeijmakers, and L. D. Samson. Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase, Proc. Natl. Acad. Sci. USA, 94: 13087-13092 (1997).

1996

B. P. Engelward, A. Dreslin, J. Christensen, D. Huszar, C. Kurahara, and L. Samson, Repair deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation induced chromosome damage and cell killing, EMBO J., 15, 945-952 (1996).

1993

B. P. Engelward, M. S. Boosalis, B. J. Chen, Z. Deng, M. J. Siciliano, and LD. Samson, Cloning and characterization of a mouse 3-methyladenine/7-methylguanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11, Carcinogenesis, 14, 175-181 (1993).

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