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Back to Topic Index 
Summary of Practical Disinfectants
Information from the National Institute of Health Laboratory
Safety Monograph:
A Supplement to the NIH Guidelines for Recombinant DNA Research,
July 197
| Disinfectants |
PRACTICAL
REQUIREMENTS |
| Type |
Category |
Use Dilution |
Lipovirus |
Broad
Spectrum |
Temp.
(C) |
Relative
Humidity, % |
| liquid |
Quat. Ammon. Cpds |
0.1-2.0% |
10 min. |
not effective |
- |
- |
| Phenolic Cpds. |
1.0-5.0% |
10 min. |
not effective |
- |
- |
| Chlorine Cpds. |
500 ppm* |
10 min. |
30 min. |
- |
- |
| Iodophor |
25-1600 ppm* |
10 min. |
30 min. |
- |
- |
| Alcohol, Ethyl |
70-85% |
10 min. |
not effective |
- |
- |
| Alcohol, Isopropyl |
70-85% |
10 min. |
not effective |
- |
- |
| Formaldehyde |
.2-8.0% |
10 min. |
30 min. |
- |
- |
| Glutaraldehyde |
2% |
10 min. |
30 min. |
- |
- |
| gas |
Ethylene Oxide |
8-23 g/cubic ft. |
60 min. |
60 min. |
37 |
30 |
| Paraformaldehyde |
0.3 g/cubic ft. |
60 min. |
60 min. |
>23 |
>60 |
| Disinfectants |
INACTIVATES |
| Type |
Category |
Vegitative
Bacteria |
Lipoviruses |
Nonlipid Viruses |
Bacterial
Spores |
| liquid |
Quat. Ammon. Cpds |
X |
X |
|
|
| Phenolic Cpds. |
X |
X |
(*) |
|
| Chlorine Cpds. |
X |
X |
X |
X |
| Iodophor |
X |
X |
X |
X |
| Alcohol, Ethyl |
X |
X |
(*) |
|
| Alcohol, Isopropyl |
X |
X |
(*) |
|
| Formaldehyde |
X |
X |
X |
X |
| Glutaraldehyde |
X |
X |
X |
X |
| gas |
Ethylene Oxide |
X |
X |
X |
X |
| Paraformaldehyde |
X |
X |
X |
X |
| Disinfectants |
IMPORTANT
CHARACTERISTICS |
| Type |
Category |
Effective
Shelf Life > 1 week (c) |
Corrosive |
Flammable |
Explosion
Potential |
Residue |
Inactivated
by Organic Matter |
Skin Irritant |
Eye Irritant |
Respiratory
Irritant |
*Toxic |
| liquid |
Quat. Ammon. Cpds |
X |
|
|
|
|
|
X |
X |
X |
X |
| Phenolic Cpds. |
X |
X |
|
|
X |
|
X |
X |
|
X |
| Chlorine Cpds. |
|
X |
|
|
X |
X |
X |
X |
X |
X |
| Iodophor |
X |
X |
|
|
X |
X |
X |
X |
|
X |
| Alcohol, Ethyl |
X |
|
X |
|
|
|
|
X |
|
X |
| Alcohol, Isopropyl |
X |
|
X |
|
|
|
|
X |
|
X |
| Formaldehyde |
X |
|
|
|
X |
|
X |
X |
|
X |
| Glutaraldehyde |
X |
|
|
|
X |
|
X |
X |
|
X |
| gas |
Ethylene Oxide |
n/a |
|
X(d) |
X(d) |
|
|
X |
X |
X |
X |
| Phenolic Cpds. |
n/a |
|
X(e) |
X(e) |
|
|
X |
X |
X |
X |
| |
* By skin or mouth or both - refer to manufacturer's
literature and/or Merck Index(c) Protected from light and
air (d) Neither flammable nor explosive in 90% CO2 or fluorinate
hydrocarbon, the usual use form(e) At concentrations of
7 to 73% by volume in air, solid exposure to open flame |
| Disinfectants |
IMPORTANT
CHARACTERISTICS |
| Type |
Category |
Work Surfaces |
Dirty
Glass-ware |
Large
Area Decon. |
Air Handling
Systems |
Portable
Equip. Surface Decon. |
Portable
Equip. Pene-trating Decon. |
Fixed
Equip. Surface Decon. |
Fixed
Equip. Pene-trating Decon. |
Optical
and Electronic Instruments |
Liquids
for Discard |
Books,
Papers |
| liquid |
Quat. Ammon. Cpds |
X |
X |
|
|
X |
|
X |
|
|
|
|
| Phenolic Cpds. |
X |
X |
|
|
X |
|
X |
|
|
|
|
| Chlorine Cpds. |
X |
X |
|
|
X |
|
X |
|
|
X |
|
| Iodophor |
X |
X |
|
|
X |
|
|
|
|
|
| Alcohol, Ethyl |
X |
X |
|
|
X |
|
X |
|
|
|
|
| Alcohol, Isopropyl |
X |
X |
|
|
X |
|
X |
|
|
|
|
| Formaldehyde |
X |
X |
|
|
X |
|
X |
|
|
|
|
| Glutaraldehyde |
X |
X |
|
|
X |
|
X |
|
|
|
|
| gas |
Ethylene Oxide |
|
|
|
|
|
X |
|
|
X |
|
X |
| Phenolic Cpds. |
|
|
X |
X |
|
X |
|
X |
X |
|
|
|
|
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