High Resolution Molecular Structure of the Tri-peptide N-f-MLF-OH
Determined by Magic Angle Spinning NMR Spectroscopy
PNAS publication


Robert G. Griffin

Director, Francis Bitter Magnet Laboratory/ Professor of Chemistry

Biomolecular solid-state NMR Winter School 2010

2008 C&EN article on Griffin Lab DNP


Francis Bitter Magnet Lab


Chemistry Department


Graduation 2003 Photos

 

 



Amyloid fibrils are self-assembled filamentous structures associated with protein deposition conditions including Alzheimer’s disease and the transmissible spongiform encephalopathies. Using solid state NMR, we have determined the first structure of a peptide in a fibril as shown in the figures above.

NEWS:

The Magnet Lab is pleased to announce that Dr. Griffin is the 2010 recipient of the ISMAR Prize.

The Magnet Lab is pleased to announce that Dr. Griffin is the 2007 recipient of the Günther Laukien Prize.