High Resolution Molecular Structure of the Tri-peptide N-f-MLF-OH
Determined by Magic Angle Spinning NMR Spectroscopy
PNAS publication

Robert G. Griffin

Director, Francis Bitter Magnet Laboratory/ Professor of Chemistry

Graduation 2003 Photos

Francis Bitter Magnet Lab
Chemistry Department


Amyloid fibrils are self-assembled filamentous structures associated with protein deposition conditions including Alzheimer’s disease and the transmissible spongiform encephalopathies. Using solid state NMR, we have determined the first structure of a peptide in a fibril as shown in the figures above.
NEWS:

The Magnet Lab is pleased to announce that Dr. Griffin is the 2007 recipient of the Günther Laukien Prize.