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I have a long standing interest in synaptic neurobiology as it applies to how the brain learns and remembers. During my graduate training in Dr. Paul F. Worley’s laboratory at Johns Hopkins Medical Institute, I used biochemical and cell biological approaches in mammalian in vitro neuronal model systems to characterize postsynaptic mechanisms of synaptic plasticity. In Dr. J. Troy Littleton’s laboratory, I will be studying the Drosophila neuromuscular junction using the genetic tools available to Drosophila coupled with in vivo electrophysiology and imaging to understand and define mechanisms of synaptic formation, function, and plasticity. Currently, I am studying the role of complexin in its regulation of neurotransmitter release. |
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