Publications 

Apgar JF, Toettcher JE, Endy D, White FM, Tidor B. Stimulus Design for Model Selection and Validation in Cell Signaling. PLoS Comput Biol. 2008 Feb 15;4(2):

Huang PH, Cavenee WK, Furnari FB, White FM. Uncovering therapeutic targets for glioblastoma: a systems biology approach. Cell Cycle. 2007 Aug;6(22):2750-4. Epub 2007 Aug 20.

White FM. Cell system perturbation for time-resolved quantification of tyrosine phosphorylation in complex samples. Conf Proc IEEE Eng Med Biol Soc. 2006;1:51-2

White FM. On the iTRAQ of kinase inhibitors. Nat Biotechnol. 2007 Sep;25(9):994-6.

Huang PH, Mukasa A, Bonavia R, Flynn RA, Brewer ZE, Cavenee WK, Furnari FB, White FM. Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12867-72. Epub 2007 Jul 23

Zhang Y, Wolf-Yadlin A, White FM. Quantitative proteomic analysis of phosphotyrosine-mediated cellular signaling networks. Methods Mol Biol. 2007;359:203-12.

Wolf-Yadlin A, Hautaniemi S, Lauffenburger DA, White FM. "Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks" Proc Natl Acad Sci U S A. 104(14):5860-5 (2007).

Wilker EW, van Vugt MA, Artim SA, Huang PH, Petersen CP, Reinhardt HC, Feng Y, Sharp PA, Sonenberg N, White FM, Yaffe MB. "14-3-3sigma controls mitotic translation to facilitate cytokinesis" Nature 446(7133):329-32 (2007).

Yaffe MB, White FM. "Signaling netwErks get the global treatment" Genome Biol 8(1):202 (2007).

Kumar N, Wolf-Yadlin A, White FM, Lauffenburger DA. "Modeling HER2 Effects on Cell Behavior from Mass Spectrometry Phosphotyrosine Data" PLoS ComputBiol. 3(1):e4 (2007).

Tannenbaum SR, White FM. "Regulation and specificity of S-nitrosylation and denitrosylation" ACS Chem Biol. 1(10):615-8 (2006).

Albeck JG, MacBeath G, White FM, Sorger PK, Lauffenburger DA, Gaudet S. "Collecting and organizing systematic sets of protein data" Nat Rev Mol Cell Biol. 7(11):803-12 (2006).

Wolf-Yadlin A, Kumar N, Zhang Y, Hautaniemi S, Zaman M, Kim HD, Grantcharova V, Lauffenburger DA, White FM. "Effects of HER2 overexpression on cell signaling networks governing proliferation and migration" Mol Syst Biol. 2:54 (2006).

Schmelzle, K. Kane, S. Gridley, S. Lienhard, G. E. White, F. M. "Temporal dynamics of tyrosine phosphorylation in insulin signaling" Diabetes 55(8), 2171-2179 (2006). [ PDF ]

Schmelzle, K. White, F. M. "Phosphoproteomic approaches to elucidate cellular signaling networks" Curr Opin Biotechnol 17(4), 406-414 (2006).

Brar GA, Kiburz BM, Zhang Y, Kim JE, White F, Amon A. "Rec8 phosphorylation and recombination promote the step-wise loss of cohesins in meiosis." Nature. 2006 May 25;441(7092):532-6. Epub 2006 May 3

Kim, JE, White, FM. "Quantitative analysis of phosphotyrosine signaling networks triggered by CD3 and CD28 costimulation in Jurkat cells" J IMMUNOL 176 (5): 2833-2843 MAR 1 2006

Moser, K White, F.M. "Phosphoproteomic Analysis of Rat Liver by High Capacity IMAC and LC-MS/MS" J. Proteome Res. 5(1), 98-104 (2006).

Behr, J.R.; Matsumoto, Y.; White, F.M.; Sasiekharan, R. “ Quantification of Isomers from a Mixture of 12 Heparin and Heparan Sulfate Disaccharides Using Tandem Mass Spectrometry” Rapid Commun. in Mass Spectrom. 19 , 2553-2562 (2005).

Kim, J.E.; Tannenbaum, S.R.; White, F.M. “Global phosphoproteome of HT-29 human colon adenocarcinoma cells” J. Proteome Res. 4 , 1339-1326 (2005).

Zhang, Y; Wolf-Yadlin, A.; Pappin, D.J.; Rush, J.; Lauffenburger, D.A.; White, F.M. “Time resolved mass spectrometry of tyrosine phosphorylation sites in the EGF receptor signaling network reveals dynamic modules” Mol. Cell. Proteomics 4 , 1240-1250 (2005).

Chen, W.G.; White, F.M. “Proteomic Analysis of Cellular Signaling” Expert Rev. Proteomics 1 , 343-354 (2004).

Zarling, A.H.; Luckey, C.J.; Marto , J.A.; White, F.M.; Brame, C.J.; Lehner, P. J.; Cresswell, P.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.H.“Tapasin is a facilitator, not an editor, of HLA-B8 peptide binding” J. Immunol. 171 , 5287-5295 (2003).

Saibil, S.D.; Ohteki, T.; White, F.M.; Luscher, M.; Zakarian, A.; Elford, A.; Shabanowitz, J.; Nishina, H.; Hugo, P.; Penninger, J.; Barber, B.; Hunt, D.F.; Ohashi, P.S. “Weak agonist self-peptides promote selection and tuning of virus-specific T cells”, Eur. J. Immunol.33, 685-696 (2003).

Ficarro, S.B.; Chertihin, O.; Westbrook, V.A.; White, F.M.; Jayes, F.; Kalab, P.; Marto, K.A.; Shabanowitz, J.; Herr, J.C.; Hunt, D.F.; Visconti, P.E. “Phosphoproteome of capacitated human sperm”, J. Biol. Chem. 278, 11579-11589 (2003).

Lippolis, J.D.; White, F.M.; Marto, J.A.; Luckey, C.J.; Bullock, T.N.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.E. “ Analysis of MHC Class II Antigen Processing by Quantitation of Peptides that Constitute Nested Sets”, J. Immunol.169 , 5089-5097 (2002).

Goeli, D.; Ficarro, S.B.; Kwiek, J.J.; Aaronson, D.; Hancock, M.; Catling, A.D.; White, F.M.; Christian, R.E.; Settlage, R.E.; Shabanowitz, J.; Hunt, D.F.; Weber, M.J. “Androgen receptor phosphorylation – regulation and identification of the phosphorylation sites”, J. Biol. Chem., 277, 29304-29314 (2002).

Flyer, D.C.; Ramakrishna, V.; Miller, C.; Myers, H.; McDaniel, M.; Root, K.; Flournoy, C.; Engelhard, V.H.; Canaday, D.H.; Marto, J.A.; Ross, M.M.; Hunt, D.F.; Shabanowitz, J.; White, F.M. “Identification by mass spectrometry of CD8+-T-Cell Mycobacterium tuberculosis epitopes within the Rv0341 gene product”, Infect. Immun.70, 2926-2932 (2002).

Ficarro, S.B.; McCLeland, M.L.; Stukenberg, P.T.; Burke, D.J.; Ross, M.M.; Shabanowitz, J.; Hunt, D.H.; White, F.M. “Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae”, Nat. Biotechnol.20, 301-305 (2002).

Nepom, G.T.; Lippolis, J.D.; White, F.M.; Masewicz, S.; Marto, J.A.; Herman, A.; Luckey, C.J.; Falk, B.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.H. “Identification and modulation of a naturally processed T-cell epitope from the diabetes-associated autoantigen hGAD65”, Proc. Nat. Acad. Sci.98, 1763-1768 (2001).

Luckey, C.J.; Marto, J.A.; Partridge, M.; Hall, E.; White, F.M.; Lippolis, J.D.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.H. “Differences in the expression of Human MHC class I alleles and their associated peptides in the presence of proteasome inhibitors”, J. Immunol., 167, 1212-1221 (2001).

Gimenez-Bonafe, P.; Laszczak, M.; Kassinsky, H.E.; Lemke, M.J.; Lewis, J.D.; Iskandar, M.; He, T.; Ikonomou, M.G.; White, F.M.; Hunt, D.F.; Chiva, M.; Ausio, J. “Characterization and evolutionary relevance of the sperm nuclear basic proteins from stickleback fish”, Mol. Repro. and Dev . 57, 185-193 (2000).

Zarling, A.L.; Ficarro, S.B.; White, F.M.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.H. “Phosphorylated peptides are naturally processed and presented by MHC class I molecules in vivo”, J. Exp. Med. 192 , 1755-1762 (2000).

Huberman, A.; Aguilar, M.B.; Navarro-Quiroga, I.; Ramos, L.; Fernandez, I.; White, F.M.; Hunt, D.F.; Shabanowitz, J. “A hyperglycemic peptide hormone from the Caribbean shrimp Penaeus (litopenaeus) schmitti”, Peptides 21, 331-338 (2000).

Crotzer, V.L.; Christian, R.E.; Brooks, J.M.; Shabanowitz, J.; Settlage, R.E.; Marto, J.A.; White, F.M.; Rickinson, A.B.; Hunt, D.F.; Engelhard, V.H. “Immunodominance among EBV-derived epitopes restricted by HLA-B27 does not correlate with epitope abundance in EBV-transformed B-lymphoblastoid cell lines”, J. Immunol. 164, 6120-6129 (2000).

Pierce, R.A.; Field, E.D.; den Haan, J.M.M.; Caldwell, J.A.; White, F.M.; Marto, J.A.; Wang, W.; Frost, L.M.; Blokland, E.; Reinhardus, C.; Shabanowitz, J.; Hunt, D.F.; Goulmy E.; Engelhard V.H. “Cutting edge: The HLA-A*0101-restricted HY minor histocompatibility antigen originates from DFFRY and contains a cysteinylated cysteine residue as identified by a novel mass spectrometric technique”, J. Immunol. 163, 6360-6364 (1999).

Shabanowitz, J.; Settlage, R.E.; Marto, J.A.; Christian, R.E.; White, F.M.; Russo, P.S.; Martin, S.E.; Hunt, D.F. “Sequencing the Primordial Soup”, In Mass Spectrometry in Biology and Medicine, A.L. Burlingame, S.A. Carr, and M.A. Baldwin, eds. Humana Press, Totowa, N.J. (1999)

Rodgers, R.P.; White, F.M.; Hendrickson, C.L.; Marshall, A.G.; Andersen, K.V. “Resolution, Elemental Composition, and Simultaneous Monitoring by Fourier Transform Ion cyclotron Resonance Mass Spectrometry of Organosulfur Species Before and After Diesel Fuel Processing", Anal. Chem. 70, 4743-4750 (1998).

Rodgers, R.P.; White, F.M.; McIntosh, D.G.; Marshall, A.G. “5.6 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer for Analysis of Volatile Complex Mixtures”, Rev. Sci. Inst. 69, 2278-2284 (1998).

Emmett, M.R.; White, F.M.; Hendrickson, C.L.; Shi. S.D.-H.; Marshall, A.G. “Application of Micro-Electrospray Liquid Chromatography Techniques to FT-ICR MS to Enable High-Sensitivity Biological Analysis”, J. Am. Soc. Mass Spectrom. 9, 333-340 (1998).

Jackson, G.S.; White, F.M.; Hammill, C.L.; Clark, R.C.; Marshall, A.G. "Gas Phase Dehydrogenation of Saturated and Aromatic Cyclic Hydrocarbons by (Pt n) +, n = 1-4", J. Am. Chem Soc. 119, 7567-7572 (1997).

Milgram, K.E.; White, F.M.; Goodner, K.L.; Watson, C.H.; Koppenaal, D.W.; Baringa, C.J.; Smith, B.H.; Winefordner, J.D.; Marshall, A.G.; Houk, R.S.; Eyler, J.R. "High Resolution Inductively Coupled Plasma Fourier Transform Ion Cyclotron Resonance Mass Spectrometry” Anal. Chem. 69, 3714-3721 (1997).

Senko, M.W.; Hendrickson, C.L.; Pasa-Tolic, L.; Marto, J.A.; White, F.M.; Guan, S.; Marshall, A.G. "Electrospray Ionization Fourier Transform Ion Cyclotron Resonance at 9.4 Tesla", Rapid Commun. in Mass Spectrom. 10, 1824-1828 (1996).

White, F.M.; Marto, J.A.; Marshall, A.G. "An External Source 7 Tesla FT-ICR Mass Spectrometer with Electrostatic Ion Guide", Rapid Commun. Mass Spectrom. 10,1845-1849 (1996).

Solouki, T.; Marto, J.A.; White, F.M.; Guan, S.; Marshall, A.G. "Attomole Biomolecule Mass Analysis by Matrix-Assisted Laser Desorption/Ionization Fourier Transform Ion Cyclotron Resonance", Anal. Chem. 67, 4139-4144 (1995).

Marto, J.A.; White, F.M.; Seldomridge, S.; Marshall, A.G. "Structural Characterization of Phospholipids by Matrix-Assisted Laser Desorption/Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry", Anal. Chem. 67, 3979-3984 (1995).

Kim, H.J.; Ball, D.; Giles, J.; White, F.M. "Analysis of Thermally Produced Compounds in Food by Thermospray Liquid Chromatography-Mass Spectrometry and Gas Chromatography-Mass Spectrometry", J. Agri. Food Chem. 42, 2812-16 (1994).

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