Mouse Line

Original publication name: CD33/Siglec-3

Colony code name: CC

Gene symbol: Cd33

Gene name(s): Siglec-3, mCD33, gp67

Protein name: Sialic acid-binding Ig superfamily lectin 3

Chromosome: 7

Reported function: Sialic acid-recognizing cell-surface lectin, binding to short O-linked glycans of some mucins, weak binding to sialyl-Tn epitope

Genomic DNA source: 129/SvJ

Mutation type: Neo replacement of exons 1-5

ES cell line: R1

Current genetic background: C57Bl/6 (13 generations backcrossed)

Name of contributing investigator: Varki A.

Name of institution: University of California, San Diego, School of Medicine

Primary reference: Brinkman-Van der Linden et al. Mol Cell Biol. 2003;23(12):4199-4206. [PubMed]